Dennis J. Dlugos
Professor of Neurology at the Children's Hospital of Philadelphia
Director, Pediatric Epilepsy Program, Division of Neurology, The Children's Hospital of Philadelphia
Associate Dean for UME Science and Discovery Curriculum, Perelman School of Medicine at the University of Pennsylvania
Department: Neurology
Contact information
Division of Neurology
Children's Hospital of Philadelphia
34th Street and Civic Center Blvd
The Hub for Clinical Collaboration
10th floor, Room 10537
Philadelphia, PA 19104
Children's Hospital of Philadelphia
34th Street and Civic Center Blvd
The Hub for Clinical Collaboration
10th floor, Room 10537
Philadelphia, PA 19104
Office: 215-590-1719
Email:
dlugos@email.chop.edu
dlugos@email.chop.edu
Education:
B.A. (Theology)
Loyola Marymount University, Los Angeles, CA, 1983.
M.D. (Medicine)
Columbia University College of Physicians & Surgeons, New York, NY, 1988.
M.S.C.E (Clinical Epidemiology)
Master’s of Science in Clinical Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA, 2002.
B.A. (Theology)
Loyola Marymount University, Los Angeles, CA, 1983.
M.D. (Medicine)
Columbia University College of Physicians & Surgeons, New York, NY, 1988.
M.S.C.E (Clinical Epidemiology)
Master’s of Science in Clinical Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA, 2002.
Post-Graduate Training
Intern in Pediatrics, National Naval Medical Center, Bethesda, MD, 1988-1989.
Resident in Pediatrics, Thomas Jefferson University & Alfred I. Dupont Institute, Philadelphia, PA & Wilmington, DE, 1993-1994.
Resident in Neurology/Child Neurology, University of Pennsylvania Medical Center & The Children’s Hospital of Philadelphia, Philadelphia , 1994-1997.
Fellow in Epilepsy and Clinical Neurophysiology, The Children’s Hospital of Philadelphia, Philadelphia, PA, 1997-1999.
Intern in Pediatrics, National Naval Medical Center, Bethesda, MD, 1988-1989.
Resident in Pediatrics, Thomas Jefferson University & Alfred I. Dupont Institute, Philadelphia, PA & Wilmington, DE, 1993-1994.
Resident in Neurology/Child Neurology, University of Pennsylvania Medical Center & The Children’s Hospital of Philadelphia, Philadelphia , 1994-1997.
Fellow in Epilepsy and Clinical Neurophysiology, The Children’s Hospital of Philadelphia, Philadelphia, PA, 1997-1999.
Certifications
Neurology with Special Qualifications in Child Neurology, American Board of Psychiatry and Neurology, 1998.
Pediatrics (1998 - 2012), American Board of Pediatrics, 1998.
Clinical Neurophysiology (1999-2009), American Board of Psychiatry and Neurology, 1999.
Clinical Neurophysiology with Special Qualifications in Epilepsy Monitoring, American Board of Clinical Neurophysiology, 1999.
Epilepsy, American Board of Psychiatry and Neurology, 2013.
Permanent linkNeurology with Special Qualifications in Child Neurology, American Board of Psychiatry and Neurology, 1998.
Pediatrics (1998 - 2012), American Board of Pediatrics, 1998.
Clinical Neurophysiology (1999-2009), American Board of Psychiatry and Neurology, 1999.
Clinical Neurophysiology with Special Qualifications in Epilepsy Monitoring, American Board of Clinical Neurophysiology, 1999.
Epilepsy, American Board of Psychiatry and Neurology, 2013.
Description of Research Expertise
Epilepsy EpidemiologyEpilepsy Genetics
Clinical Prediction Models
Description of Clinical Expertise
Pediatric EpilepsyEpilepsy Genetics
Epilepsy Surgery
EEG
Clinical Neurophysiology
Selected Publications
Ferrer M, Jandhyala N, Pellinen J, Greenwood H, Thio LL, Dlugos D, Park KL, Kanner AM, French J, for Human Epilepsy Project Investigators : Delayed Diagnosis in Adolescent-Onset Focal Epilepsy: Impact on Morbidity and Mental Health. Epilepsia doi.org/10.1111/epi.18434, 2025.Dlugos D, Lozano M, DiVentura B, Farfel G, Shellhaas RA, Sullivan JE, Thio LL, Kessler SK, Sadleir L, French J: Appropriate selection of participants in pediatric developmental and epileptic encephalopathy trials: Lessons learned and future opportunities. Epilepsia(10.1111/epi.18440), 2025.
Omurtag A, Abdulbaki S, Thesen T, Waechter R, Landon B, Evans R, Dlugos D, Chari G, LaBeaud AD, Hassan YI, Fernandes M, Blackmon K: Disruption of functional network development in children with prenatal Zika virus exposure revealed by resting-state EEG. Scientific Reports 15: 6346, 2025.
Alkofer M, Yang C, Ganglberger W, Beal J, Hegde M, Kang JY, Yoo JY, Gelfand MA, Thio LL, Kutluay E, Campbell Z, Schmitt S, Gleichgerrcht E, Waterhouse E, Lopez MR, Eisenschenk S, Galanti M, Singh RK, Wills KE, Meulenbrugge EJ, Dlugos D, Dean B, Halford J, Goldenholz D, Jing J, Thomas R, Westover MB: Automated detection of interictal epileptiform discharges with few electroencephalographic channels. Epilepsia doi.org/10.1111/epi.18431, 2025.
Jandhyala N, Ferrer Socorro M, Greenwood H, Pellinen J, Dlugos D, Park K, Thio L, French J: Unrecognized Focal Non-Motor Seizures in Adolescents Presenting to Emergency Departments. Neurology 102: e209389, 2024.
Ellis CA, Tu D, Oliver KL, Mefford HC, Hauser WA, Buchhalter J, Epstein MP, Cao Q, EPGP Consortium (including Dlugos DJ), Epi4K Consortium (including Dlugos DJ), Berkovic SF, Ottman R: Familial aggregation of seizure outcomes in four familial epilepsy cohorts. Epilepsia Page: 10.1111/epi.18004, 2024.
Epi4K Consortium (including Dlugos DJ): The role of copy number variants in the genetic architecture of common familial epilepsies. Epilepsia 65: 792-804, 2024.
Perry MS, Scheffer IE, Sullivan J, Brunklaus A, Boronat S, Wheless J, Laux L, Patel AD, Roberts CM, Dlugos D, Holder D, Knupp KG, Lallas1 M, Phillips S, Segal E, Smeyers P, Lal1 D, Wirrell E, Zuberi S, Brünger T, Wojnaroski M, Maru B, O’Donnell P, Morton M, James E, Vila C, Huang N, Gofshteyn JS, Rico S: Severe Communication Delays Are Independent of Seizure Burden and Persist Despite Contemporary Treatments in SCN1A+ Dravet Syndrome: Insights from the ENVISION Natural History Study. Epilepsia 65: 322-337, 2024.
Bozorg A, Beller C, Jensen L, Arzimanoglou A, Chiron C, Dlugos D, Gaitanis J, Wheless J, McClung C: Pitfalls of Using Video-EEG for a Trial Endpoint in Children Aged <4 Years with Focal Seizures. Annals of Clinical and Translational Neurology Page: 10.1002/acn3.51999, 2024.
Molisani SE, Parikh D, DiGiovine M, Dlugos D, Fitzgerald MP, Fried L, Helbig I, Kessler SK, McDonnell PP, Melamed S, Prelack MS, Sharif U, Tefft S, Tencer J, Witzman S, Shaw K, Abend NS: A quality improvement initiative to improve folic acid supplementation counseling for adolescent females with epilepsy. Epilepsia Page: 10.1111/epi.17723, July 2023.