Corinde Wiers, PhD

Selected Publications

Wiers CE, Vendruscolo LF, van der Veen JW, Manza P, Shokri-Kojori E, Kroll DS, Feldman DE, McPherson KL, Biesecker CL, Zhang R, Herman K, Elvig SK, Vendruscolo JCM, Turner SA, Yang S, Schwandt M, Tomasi D, Cervenka MC, Fink-Jensen A, Benveniste H, Diazgranados N, Wang GJ, Koob GF, Volkow ND. Ketogenic diet reduces alcohol withdrawal symptoms in humans and alcohol intake in rodents. Sci Adv. 2021 Apr 9;7(15):eabf6780.

Wiers CE, Cunningham SI, Tomasi DG, Ernst T, Chang L, Shokri-Kojori E, Wang GJ, Volkow ND. Elevated thalamic glutamate levels and reduced water diffusivity in alcohol use disorder: Association with impulsivity. Psychiatry Res Neuroimaging. 2020 Sep 10;305:111185.

Kim SW, Wiers CE, Tyler R, Shokri-Kojori E, Jang YJ, Zehra A, Freeman C, Ramirez V, Lindgren E, Miller G, Cabrera EA, Stodden T, Guo M, Demiral ŞB, Diazgranados N, Park L, Liow JS, Pike V, Morse C, Vendruscolo LF, Innis RB, Koob GF, Tomasi D, Wang GJ, Volkow ND. Influence of alcoholism and cholesterol on TSPO binding in brain: PET [(11)C]PBR28 studies in humans and rodents. Neuropsychopharmacology. 2018 Aug;43(9):1832-1839.

Wiers CE, Shokri-Kojori E, Wong CT, Abi-Dargham A, Demiral ŞB, Tomasi D, Wang GJ, Volkow ND. Cannabis Abusers Show Hypofrontality and Blunted Brain Responses to a Stimulant Challenge in Females but not in Males. Neuropsychopharmacology. 2016 Sep;41(10):2596-605.

Wiers CE, Stelzel C, Gladwin TE, Park SQ, Pawelczack S, Gawron CK, Stuke H, Heinz A, Wiers RW, Rinck M, Lindenmeyer J, Walter H, Bermpohl F. Effects of cognitive bias modification training on neural alcohol cue reactivity in alcohol dependence. Am J Psychiatry. 2015 Apr;172(4):335-43.

Grants and Funding

National Institute on Alcohol Abuse and Alcoholism - R00 AA026892 (Wiers): Ketone ester intervention in alcohol use disorder

Brain & Behavior Research Foundation - NARSAD Young Investigator Grant (Wiers): Effects of a ketone ester on alcohol consumption

ITMAT/tbic Pilot grant (Wiers & Dubroff): Relationship between brain and heart glucose metabolism in alcohol use disorder

Bio

Corinde E. Wiers, PhD is Assistant Professor of Psychiatry and Radiology at the Perelman School of Medicine. She received her PhD in Psychology from the Berlin School of Mind and Brain and Freie Universität Berlin and completed a Postdoctoral Fellowship at the NIH/NIAAA in Bethesda MD under mentorship of Dr. Nora Volkow. Her research focuses on neurocognitive underpinnings of substance use disorders using PET and MRI. She currently investigates the effects of metabolic ketosis on brain energetics, alcohol withdrawal and consumption in alcohol use disorder.

Media Coverage

https://www.aaas.org/news/keto-diet-may-help-manage-alcohol-use-disorder-withdrawal
https://www.dietdoctor.com/low-carb/keto/alcohol
https://www.deutschlandfunk.de/ketogene-diaet-spezielle-ernaehrung-reduziert.676.de.html?dram:article_id=495592