Perelman School of Medicine at the University of Pennsylvania

Herpes Virus Symposium

Agenda 2019

8:00 am REGISTRATION AND BREAKFAST
        8:25 am Erle Robertson Ph.D., Vice Chair of Otorhinolaryngology–Head and Neck Surgery, Professor of Microbiology Perelman School of Medicine, University of Pennsylvania 
♦   Opening Remarks 
First Session  Robert Yarchoan, MD, NIH/ National Cancer Institute  
♦   Moderator of first session
 8:30–9:00 am Sumita Bhaduri-McIntosh, MD, PhD, Associate Professor, Pediatrics & Molecular Genetics and Microbiology, University of Florida
♦   “Diabetes-related Inflammasome Components Trigger the Replication switch of
      Epstein-Barr virus”
9:00–9:15 am Claude Krummenacher, PhD, Assistant Professor, Rowan University 
♦   “Interaction between the HSV receptor nectin-1 and the natural killer cell receptor
      CD96”
9:15–9:30 am Jason Lamontagne, PhD, P. Lieberman lab, The Wistar Institute
♦   "Integrated analysis of EBV reprogramming of primary B cells"
9:30–9:45 am♦ Megan Lloyd, PhD, J. Moffat Lab, SUNY Upstate Medical University
♦   “A novel human skin tissue model to study HCMV and evaluate antiviral drugs in vivo”
9:45–10:00 am Joseph Dybas, PhD, Matthew D Weitzman Lab, Perelman School of Medicine
♦   “Quantitative proteomics reveals host protein targets of HSV ICP0-mediated ubiquitin”
10:00–10:30 am COFFEE BREAK
Second Session  Ileana M Cristea, PhD,  Professor of Molecular Biology at Princeton University   
♦   Moderator of second session
10:30–11:30 am Lawrence S. Young, PhD, Pro-Dean, Warwick Medical School, Director of the Warwick Cancer Research Centre, University of Warwick, UK 
♦     Gertrude and Werner Henle Lectureship Keynote Speaker
♦   
“The role of Epstein-Barr virus in Nasopharyngeal Carcinoma: lessons in cancer
      pathogenesis and treatment”
11:30–11:45 am Hyun Jin Kwun, Ph.D. Assistant Professor Department of Microbiology and Immunology Penn State University College of Medicine
♦   “Surface charge of Merkel cell polyomavirus small t antigen:
      a key determinant of cell transformation"
11:45–12:00 am Robert Yarchoan, MD, Senior Investigator HIV and AIDS Malignancy Branch, National CanceRobert Yarchoan, MD, Senior Investigator HIV and AIDS Malignancy Branch, National Cancer Instituter Institute
♦   “Activation of KSHV vIL-6 (ORF K2) and thymidine kinase (ORF21) by spliced XBP-1:
      Implications for pathogenesis and therapy”
 12:00–1:15 pm LUNCH
Third session  Paul Lieberman, PhD,  Hilary Koprowski, M.D., Endowed Professor The Wistar Institute 
♦   Moderator of third session
1:15–1:45 pm Robert P. Ricciardi, MA, PhD, Chair and Professor of Department of Microbiology Penn Dental
♦   “Developing an Antiviral Stapled-Peptide to Treat Herpes Ocular Keratitis, the Leading
      Cause of Blindness in the World”
1:45–2:00 pm Sean Lawler, PhD, Assistant Professor at Brigham and Women's Hospital
♦  “Cytomegalovirus promotes brain tumor growth via pericyte recruitment and
     angiogenesis”
2:00–2:15 pm Kai Wu, PhD, Thomas Shenk Lab, Department of Molecular Biology, Princeton University
♦   “Friend or Foe? PDGF receptor alpha as a cellular receptor and an antagonist for human
      cytomegalovirus"
2:15–2:30 pm Krystal Lum, Graduate Student, Ileana Cristea Lab,  Princeton University
♦   “Interactome and Proteome Dynamics Uncover Antagonistic Relationship between
      Pathogen Sensing Factors cGAS and OASL"
2:30–2:45 pm Daniel Depledge, PhD, Assistant Professor, New York University School of Medicine
♦   "Deciphering complex herpesviral transcriptomes using direct RNA sequencing"
2:45–3:15 pm AFTERNOON BREAK
Final Session  Laurie Krug Lab, Stony Brook University
♦   Moderator of final session
3:15–3:45 pm Yan Yuan, Ph.D., Professor, Department of Microbiology, University of Pennsylvania
♦   “KSHV Infection of Mesenchymal Stem Cells Leads to Kaposi's sarcoma and
       Osteosarcoma”
3:45–4:00 pm Prabha Shresta PhD, Robert Yarchoan lab, NIH/NCI
♦   “Mechanisms and functional aspects of the effects of pomalidomide and related
      drugs on herpesvirus-induced downregulation of surface markers” 
4:00–4:15 pm Kevin Egan, PhD, Harvey M. Friedman lab, University of Pennsylvania 
♦  “An HSV-2 gC2/gD2/gE2 trivalent vaccine provides cross protection against high dose
     intravaginal HSV-1 challenge"
4:15–4:30 pm Kathyrn Stein, PhD Candidate, Domenico Tortorella Lab, Icahn School of Medicine at Mount Sinai
♦    “Discovery of CD46 as a cell-type cytomegalovirus entry factor”   
4:30–4:45 pm Metthew Lam, PhD, Elizabeth White lab,  University of Pennsylvania
♦    “Regulation of IL-1-mediated inflammation by HPV oncoproteins”
4:45 pm RECEPTION

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