Agenda 2025

                    Herpes Virus Symposium Agenda 2025

8:00 am   REGISTRATION AND BREAKFAST
8:25 am  Erle Robertson Ph.D., Vice Chair of Otorhinolaryngology–Head and Neck Surgery, Professor of Microbiology Perelman School of Medicine, University of Pennsylvania, PA. 
♦ Opening Remarks 
First Session  Moderator:  Dr. Yanming Du, Ph.D., Professor, Baruch S. Blumberg Institute, Doylestown, PA
 8:30 – 9:00 am  Dr. Harvey Freedman, M.D., Professor of Medicine, University of Pennsylvania, Philadelphia, PA.
♦ “Current status of the HSV-2 gC2/gD2/gE2 trivalent mRNA-LNP vaccine for genital herpes”.
9:00 – 9:20 am  Dr. Sumita Bhaduri-McIntosh, M.D., Ph.D., Professor, Dept. of Pediatrics, University of Florida, FL.
♦ “Warning! Two danger sensing pathways reactivate EBV in DLBCL-derived lines”. 
9:20 – 9:40 am  Dr. Christoph Weigel, Ph.D., Postdoctoral fellow, Dr. Robert Baiocchi Lab, The Ohio State University, Columbus, OH.
♦ “EBV DNA methylation profiling in lymphoma reveals diagnostic applications”.
9:40 – 10:00 am  Ms. Rachel Sklutuis, Ph.D., candidate, Dr Italo tempera Lab, The Wistar Institute, Philadelphia, PA.
♦ “Epstein-Barr Virus Exploits Host NAD⁺ Metabolism to Reprogram Chromatin and Drive B Cell Transformation”.
10:00 – 10:20 am  COFFEE BREAK
Second session  Moderator: Dr. Laurie T. Krug, Ph.D., Stadtman Investigator, NCI CCR HAMB, National Institutes of Health, Bethesda, MD.
10:20 – 11:20 am  Dr. Jae U. Jung, Ph.D., The Betsy DeWindt Chair, Associate Chief of Emerging Science & Technology, Chair of Infection Biology Department, Director of Global Center for Pathogen and Human Health Research, Director of Experimental Therapeutics Program, Cleveland Clinic, Cleveland, OH.  ♦  Gertrude and Werner Henle Lectureship Keynote Speaker
♦ “Gamma herpesvirus-induced metabolic reprograming for viral malignancy”.
11:20 – 11:40 am  Dr. Greg Glenn, M.D. CEO, Pinion Immunotherapeutics, Rockville, MD.
♦ “Development of a Therapeutic mRNA Vaccine for HSV Genital Herpes”.
11:40 – 12:00 pm  Dr. Yan Yuan, Ph.D., Professor, Shandong University, China.
♦ "KSHV Infection of Mesenchymal Stem Cells Leads to Osteosarcoma". 
 12:00 – 1:20 pm   LUNCH
Third session  Moderator: Dr. Sita Awasthi, Ph.D., Associate Professor Research, University of Pennsylvania, PA.
1:20 – 1:50 pm  Dr. Stephen Schuster M.D., Professor of Medicine, University of Pennsylvania, PA.
♦ “Human Herpesvirus-related Lymphomas: Biology and Current Management”.
1:50 – 2:10 pm  Dr. Michael McIntosh, Ph.D., Associate Professor, Department of Pediatrics, University of Florida, FL.
♦ “Turning Off the Latent-to-Lytic Switch of Epstein-Barr Virus”.
2:10 – 2:30 pm  Ashwin Nair, Ph.D., Visiting Post-Doctoral fellow, Robert Yarchoan Lab, National Cancer Institute, Bethesda, MD.
♦ “ORF75 SUMOylation and SUMO-Interacting Motifs Are Essential for Its Stability and Function during KSHV Pathogenesis”.
2:30 – 2:50 pm  Mr. Matthew Tyl, Ph.D. Candidate, Dr. Ileana Cristea lab, Princeton University, Princeton, NJ.
♦ “Infection-induced lysine lactylation enables herpesvirus immune evasion”.
2:50 – 3:10 pm Ms. Jenna Nosek, Graduate Student, Dr. Neal DeLuca Lab, University of Pittsburgh, Pittsburgh, PA.
♦ “Accessibility of the HSV-1 genome throughout productive infection".
3:10 – 3:30 pm   AFTERNOON BREAK
Final Session  Moderator: Dr. Italo Tempera, Ph.D., Associate Professor, Wistar Institute, Philadelphia, PA.
3:30 – 4:00 pm  Dr. Ahmed Diab, Ph.D., Assistant Professor, University of Pennsylvania, Philadelphia, PA.
♦ “Intra-tumor heterogeneity in HPV oncogene expression as a determinant of oropharyngeal cancer progression and therapy response”.
4:00 – 4:20 pm  Dr. Anna Grosskopf, Ph.D., Postdoctoral Visiting Fellow, Dr. Laurie Krug Lab, HIV & AIDS Malignancy Branch NCI, Bethesda, MD
♦ ”Eph receptor tyrosine kinases are functional entry receptors for the murine gammaherpesvirus 68”.
4:20 – 4:40 pm  Ms. Leena Yoon, Ph.D. Candidate, Dr Paul Lieberman Lab, Wistar Institute, Philadelphia, PA.
♦ “Dynamic Immune Responses to EBV in Primary Infection and Implications for MS”.
4:40 – 5:00 pm  Dr. Mark Painter, Postdoctoral Fellow, E. John Wherry lab, University of Pennsylvania, PA.
♦ “Leveraging T cells as antigen biosensors to interrogate herpesvirus reactivation”.
5:00 pm   RECEPTION

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