Agenda 2023
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| 8:00 am | REGISTRATION AND BREAKFAST |
| 8:25 am | Erle Robertson Ph.D., Vice Chair of Otorhinolaryngology–Head and Neck Surgery, Professor of Microbiology Perelman School of Medicine, University of Pennsylvania ♦ Opening Remarks |
| First Session | Moderator: Dr. Jianxin You, PhD, Associate Professor of Microbiology, University of Pennsylvania, Philadelphia, |
| 8:30–9:00 am | Dr. Jia Zhu, Ph.D., Associate Professor, Fred Hutch Cancer Center, Seattle, WA ♦ “Innate and adaptive immune compartmentalization during ulcer-forming human HSV-2 reactivation” |
| 9:00–9:12 am | Dr. Bo Zhao, PhD, Associate Professor, Department of Medicine, Brigham and Women's Hospital, Boston, MA ♦ “Epstein-Barr virus nuclear antigen leader protein manipulates YY1 to alter host 3D genome organization and promote B cell proliferation”. |
| 9:12–9:24 am | Dr. Ayman Elguindy, PhD, Chief Scientific Officer, Viracta Therapeutics, Cardiff, CA ♦ "Targeting Epstein-Barr virus-associated malignancies using “Kick and Kill”. |
| 9:24–9:36 am | Dr. Samantha Soldan, Sr. Staff Scientist, Paul Lieberman Lab, The Wistar Institute, Philadelphia, PA ♦ “Unstable EBV latency drives inflammation in multiple sclerosis patient derived spontaneous B cells” |
| 9:36–9:48 am | Wei Bu, Staff scientist, Jeffry Cohen Lab, NIAID, NIH, Bethesda, MD ♦ “Mapping an Antigenic Site of Vulnerability on Epstein-Barr Virus Glycoprotein 42”. |
| 9:48–10:00 am | Dr. Montserrat Aguilar-Hernandez, Postdoctoral fellow, Ethel Cesarman Lab, Weill Cornell Medicine, New York, NY ♦ “Molecular landscape of EBV-associated lymphomas from people living with human immunodeficiency virus”. |
| 10:00–10:25 am | COFFEE BREAK |
| Second session | Moderator: Dr. Harvey Freedman, MD, Professor of Medicine, University of Pennsylvania, Philadelphia, PA |
| 10:30–11:30 am | Dr. Douglas R. Lowy, M.D., NIH Distinguished Investigator of Laboratory of Cellular Oncology, NCI Principal Deputy Director, Bethesda, MD ♦ Gertrude and Werner Henle Lectureship Keynote Speaker ♦ “How Mechanism has Informed Prevention and Screening for HPV-associated Cancers". |
| 11:30–11:42 am | Dr. Kai Wu, Associate Director, Moderna, Cambridge, MA ♦ “Humoral and Cellular Immunological Responses to a mRNA–based Cytomegalovirus Vaccine in Healthy Adults in a Phase 1, Randomized, Clinical Trial". |
| 11:42–11:54 am | Dr. Sarah Dremel, Postdoctoral fellow, Joseph Ziegelbauer Lab, NCI, Bethesda, MD ♦ “Regulation of host circular RNAs during alpha-, beta-, and gamma-herpesvirus infection”. |
| 11:54-12:06 | Dr. Yan Yuan, Professor, Departments of Basic & Translational Sciences and Otorhinolaryngology, University of Pennsylvania, Philadelphia, PA ♦ "KSHV Infection of Mesenchymal Stem Cell Leads to Kaposi's Sarcoma". |
| 12:10–1:25 pm | LUNCH |
| Third session | Moderator: Dr. Joseph Ziegelbauer, PhD, Deputy Chief, HIV and AIDS Malignancy Branch, Bethesda, MD |
| 1:30–2:00 pm | Dr. Italo Tempera, Associate Professor, The Wistar Institute, Philadelphia, PA ♦ “Changes in NAD Metabolism Regulate EBV Latency Through the Epigenetic Reprogramming of the Viral Genome”. |
| 2:00–2:12 pm | Dr. Ashwin Nair, Postdoctoral fellow, Robert Yarchoan Lab, NCI, NIH, Bethesda, MD ♦ “An Sp Element Contributes to the Unexpectedly High Expression of the KSHV Lytic Gene ORF75 in Kaposi’s Sarcoma Lesions”. |
| 2:12–2:24 pm | Dr. Kevin Egan, Senior Research Investigator, Harvey Friedman Lab, University of Pennsylvania, Philadelphia, PA ♦ “Trivalent HSV-1 and HSV-2 mRNA vaccines provide similar protection against high-dose HSV-1 infection in mice”. |
| 2:24–2:36 pm | Dr. Rinki Kumar, Postdoctoral Fellow, Nick Buchkovich Lab, Penn State College of Medicine, Hershey, PA ♦ “The HCMV tegument protein UL88 promotes MyD88 protein degradation”. |
| 2:36–2:48 pm | Rebecca Grande, PhD Candidate, Ian Mohr & Angus Wilson Lab, New York University School of Medicine, New York, NY ♦ “Reorganizing host RNA modification factors required for robust HCMV gene expression into transcription-dependent, subnuclear domains”. |
| 2:48-3:00pm | Dr. Claire Birkenheuer, Postdoctoral Researcher, Cornell University, Ithaca, NY ♦ “RNA polymerase promoter proximal pausing regulates transcription in a model of HSV-1 latency”. |
| 3:00–3:25 pm | AFTERNOON BREAK |
| Final Session | Moderator: Dr. Angus Wilson, PhD, Associate Professor, Department of Microbiology, NYU School of Medicine, NY |
| 3:30–4:00 pm | Dr. Laurie Krug, Stadtman Investigator, National Cancer Institute, Bethesda, MD ♦ “Kaposi sarcoma patient-derived xenografts as a preclinical model for evaluation of novel therapeutic strategies”. |
| 4:00–4:12 pm | Dr. Namrata Kumar, Postdoctoral fellow, Matthew Weitzman Lab, CHOP, Philadelphia, PA ♦ “Herpes simplex virus manipulates host DNA repair pathways for productive infection”. |
| 4:12–4:24 pm | Chloe Cavanaugh, MD/PhD Candidate, Daniel Notterman Lab, Princeton University, Princeton, NJ ♦ “Mechanism and Therapeutic Implication of Host Telomerase Modulation by Human Cytomegalovirus”. |
| 4:24–4:36 pm | Dawei Liu, PhD Candidate, Ileana Cristea Lab, Princeton University, Princeton, NJ ♦ “IFI16 phase separation via multi-phosphorylation drives innate immune signaling”. |
| 4:36–4:48 pm | Taylor Senay, PhD Candidate, Jianxin You Lab, University of Pennsylvania, Philadelphia, PA ♦ “Determining the Mechanisms of Merkel Cell Polyomavirus Host Immune Modulation”. |
| 4:48-5:00pm | Sarah Dweikat, MCIBS Candidate, Moriah Szpara lab, Pennsylvania State University, University Park, PA ♦ “Investigating viral attenuation of herpes simplex virus 1 strains isolated from adults and neonates based on a multi-parameter approach”. |
| 5:00 pm | RECEPTION |
