Agenda 2024

                    Herpes Virus Symposium Agenda 2024

8:00 am   REGISTRATION AND BREAKFAST
8:25 am  Erle Robertson Ph.D., Vice Chair of Otorhinolaryngology–Head and Neck Surgery, Professor of Microbiology Perelman School of Medicine, University of Pennsylvania 
♦ Opening Remarks 
First Session  Moderator: Dr. Harvey Freedman, MD, Professor of Medicine, University of Pennsylvania, Philadelphia, PA
 8:30 – 9:00 am  Dr. Sumita Bhaduri-McIntosh, M.D., Ph.D., Professor, Dept. of Pediatrics, University of Florida, FL
♦ “A selective HDAC3 and HDAC8 PROTAC as a novel oncolytic approach for EBV-cancers”. 
9:00 – 9:20 am  Dr. Tauseef Butt, PhD, President, Progenra Inc, Malvern, PA
♦ “Enhancing HSV-2 target protein expression by SUMO-fusion at the mRNA level”.
9:20 – 9:40 am  Dr. Sita Awasthi, Associate Professor Research, University of Pennsylvania, PA
♦ “mRNA encoding HSV mono and bispecific antibodies for mitigation of herpes virus associated diseases.”
9:40 – 10:00 am  Dr. Anna Grosskopf, PhD, Postdoctoral Visiting Fellow, Dr. Laurie Krug Lab, HIV & AIDS Malignancy Branch NCI, Bethesda, MD
♦ ”Eph receptor tyrosine kinases are functional entry receptors for the murine gammaherpesvirus 68”.
10:00 – 10:30 am  COFFEE BREAK
Second session  Moderator: Dr. Laurie Krug, Stadtman Investigator, National Cancer Institute, Bethesda, MD
10:30 – 11:30 am  Dr. Robert Yarchoan, MD, Chief, HIV and AIDS Malignancy Branch, CCR, NCI, Bethesda MD and Director, Office of HIV and AIDS Malignancy, NCI  ♦  Gertrude and Werner Henle Lectureship Keynote Speaker
♦ “KSHV-Associated Diseases: Insights on Pathogenesis and Novel Approaches to Treatment”.
11:30 – 11:50 am  Dr. Paula Krosky, Director, Merck, West Point, PA
♦ “Broad spectrum inhibitors of herpesvirus replication”.
11:50am – 12:10 pm  Dr. Dipayan Bose, PhD, Research Associate, Dr. Erle Robertson Lab, University of Pennsylvania, Philadelphia, PA
♦ "Differential IFN signaling due to altered M6A modification in host epitranscriptome during lytic EBV infection". 
 12:10 – 1:30 pm   LUNCH
Third session  Moderator: Dr. Jianxin You, Professor, University of Pennsylvania, Philadelphia, PA
1:30 – 2:00 pm  Dr. Joseph Ziegelbauer, PhD, Deputy Chief, HIV and AIDS Malignancy Branch, Bethesda, MD
Spatial Transcriptomics of Patients with Kaposi Sarcoma Identifies Mechanisms of Immune Evasion”.
2:00 – 2:20 pm  Dr. Michael McIntosh, PhD, Associate Professor, Department of Pediatrics, University of Florida, FL
♦ “Genomic Analysis of Synthetic Lethal Sensitive and Resistant Cell Lines Derived from EBV+ and EBV– Diffuse Large B-cell Lymphomas”.
2:20 – 2:40 pm  Ms. Samantha Sustek, PhD Candidate, Paul Lieberman Lab, Wistar Institute, Philadelphia, PA
♦ “Cryo-EM studies of EBNA1 in complex with human telomeric factors TRF2-hRAP1 at the EBV oriP”.
2:40 – 3:00 pm  Dr. Malay Kumar Sannigrahi, Research Associate, Dr. Dev Basu Lab, University of Pennsylvania, Philadelphia, PA
♦ “Variation in HPV E6-mediated repression of the PGC-1α/ERRα axis determines oropharyngeal cancer treatment responses and defines new therapeutic targets”.
3:00 – 3:30 pm   AFTERNOON BREAK
Final Session  Moderator: Dr. Yanming Du, PhD, Professor, Baruch S. Blumberg Institute, Doylestown, PA
3:30 – 4:00 pm  Dr. Ahmed Diab, PhD, University of Pennsylvania, Philadelphia, PA
♦ “WEE1 inhibition triggers tumor microenvironment-dependent antitumor immunity against HPV+ HNSCC tumors”.
4:00 – 4:20 pm  Ms. Ameera Mungale, PhD Candidate, Joseph M. Ziegelbauer Lab National Cancer Institute, Bethesda, MD
♦ “Vascular endothelial growth factor receptor 3 (VEGFR3/FLT4) regulates the KSHV replication cycle”.
4:2 – 4:40 pm  Taylor Senay, PhD Candidate, Jianxin You Lab, University of Pennsylvania, Philadelphia, PA
♦ “Merkel cell polyomavirus protein ALTO modulates TBK1 activity to support persistent infection”.
4:40 – 5:00 pm  Dr. Anuj Ahuja, Postdoctoral Fellow, Dr. Ethel Cesarman Lab, Weill Cornell Medical College, New York, NY
♦ “Targeting HERV-K by ART drugs for the treatment of Primary Effusion Lymphoma”.
5:00 pm   RECEPTION

Download Symposium Agenda