Perelman School of Medicine at the University of Pennsylvania

Herpes Virus Symposium

Agenda 2018

University of Pennsylvania

Herpesvirus: Pathogenesis & Cancer symposium

Friday, June 1  2018

8:00 am REGISTRATION AND BREAKFAST
        8:25 am Erle Robertson Ph.D., Vice Chair of Otorhinolaryngology–Head and Neck Surgery, Professor of Microbiology Perelman School of Medicine, University of Pennsylvania 
♦   Opening Remarks 
First Session  Laurie Krug, Ph.D., Associate Professor of Molecular Genetics and Microbiology, Stony Brook University   ♦   Moderator of first session
 8:30–9:00 am Dr. Sita Awasthi, Ph.D., Research Associate Professor Infectious Disease Division, University of Pennsylvania
♦   “An mRNA based trivalent genital herpes vaccine: Sterilizing immunity as a real
      possibility”
9:00–9:15 am Dr. David Davis, Staff Scientist, NCI/NIH 
♦   “Pomalidomide Increases Immune Surface Markers in Herpesvirus-infected Cells and
     Increases NK  KillinG"
9:15–9:30 am Qiwen Dong, Laurie Krug Lab, Stony Brook University
♦   "Coordinated loss of uracil excision and dUTP metabolism destabilizes the viral genome
      and impairs gammaherpesvirus pathogenesis in mice"
9:30–9:45 am♦ Jillian Carmichael, John W. Wills Lab, Penn State University College of Medicine
♦   “Closing the door on HSV-1 cell-to-cell spread”
9:45–10:00 am Andrea Gardner, Ethel Cesarman Lab,  Weill Cornell Medicine College
♦   “Nucleic Acid Amplification Testing for Diagnosis of Kaposi Sarcoma in Africa”
10:00–10:30 am COFFEE BREAK
Second Session  Jianxin You Ph.D., Associate Professor of Microbiology,  Perelman School of MedicineUniversity of Pennsylvania   ♦   Moderator of second session
10:30–11:30 am Edward S Mocarski, Ph.D., Robert W. Woodruff Professor, Professor of Microbiology and Immunology  ♦  Gertrude and Werner Henle Lectureship Keynote Speaker
♦   “Alternative Cell Death Pathways in Antiviral Host Defense”
11:30–11:45 am Anna Serquina, NIH/NCI, Joseph Ziegelbauer Lab, HIV and AIDS Malignancy Branch, National Cancer Institute
♦   “Viral microRNAs Inhibit the Cholesterol Biosynthesis Pathway and
      25-hydroxycholesterol Inhibits KSHV  and EBV Infections”
11:45–12:00 am Nathan Krump, Jianxin You Lab, University of Pennsylvania
♦   “Dissecting the Inflammatory Response to Merkel Cell Polyomavirus Infection”
 12:00–1:15 pm LUNCH
Third Session  Moriah Szpara Ph.D., Assistant Professor of Biochemistry & Molecular Biology,
Penn State University
  ♦   Moderator of third session
1:15–1:45 pm Gary H. Cohen, Ph.D., Professor Department of Microbiology, University of Pennsylvania
♦   “An approach to antigenically  “stealth” oncolytic herpes simplex viruses to the human
      immune system”
1:45–2:00 pm Christine King, Ph.D., Assistant Professor of Microbiology & Immunology, SUNY Upstate Medical University
♦  “Cheap & Easy: Targeting the non-negotiable to improve KS therapy”
2:00–2:15 pm Maciej Nogalski Ph.D., Thomas Shenk Lab, Department of Molecular Biology, Princeton University
♦   “The Induction of a Tumor-Specific Endogenous Repetitive Element by Herpesviruses"
2:15–2:30 pm Colleen Mangold, Moriah L. Szpara Lab, Penn State University
♦   “Examination of changes in host gene transcription following HSV-1 infection of human
      neuronal-like cells”
2:30–2:45 pm Colleen Harrington, Andrei Thomas-Tikhonenko Lab, Children's Hospital of Philadelphia
♦   "Therapeutic Targeting of GSK3 in EBV-associated Myc-driven B-cell Malignancies"
2:45–3:15 pm AFTERNOON BREAK
Final Session  Ayman El-Guindy Ph.D., Associate Professor of Pediatrics, Yale University
♦   Moderator of final session
3:15–3:45 pm Elizabeth White Ph.D., Assistant Professor of Otorhinolaryngology: Head And Neck Surgery, University of Pennsylvania
♦   “High-risk HPV E7 degrades the tumor suppressor PTPN14 to limit keratinocyte
      differentiation”
3:45–4:00 pm Jinlin Li, Ayman El-Guindy Lab, Yale University 
♦   “Phosphorylation regulates the function of the Epstein-Barr virus pre-initiation complex in transcription of late genes” 
4:00–4:15 pm Rajnish Singh Ph.D., Robertson Lab, Perelman School of Medicine, University of Pennsylvania 
♦  “Hypoxia-mediated metabolic reprogramming of KSHV infected B-cells
4:15–4:30 pm Lisa Akhtar, Matthew D Weitzman Lab, Perelman School of Medicine,
University of Pennsylvania

♦    “Neurovirulence determinants of neonatal HSV disease”   
4:30–4:45 pm Xinlei Sheng, Ileana Cristea Lab,  Princeton University
♦    “Dynamic orchestration of protein acetylation during HCMV infection”
4:45 pm RECEPTION

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