Perelman School of Medicine at the University of Pennsylvania

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    Rebecca Wells Lab, Department of Medicine

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    Dr. June with June lab members, The Center for Cellular Immunotherapies

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Latest News

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  • Amyloid removal may reduce tau buildup and neurodegeneration in Alzheimer’s disease July 13, 2026 In an Alzheimer’s disease patient’s brain, regions cleared of amyloid had little tau; nearby areas with persistent amyloid had greater signs of damage.
  • Novel medicine for rare disease prompts $10M gift for trials July 06, 2026 The Clayco Foundation award will go toward safety trials of a new small molecule drug aimed at treating RVCL, a rare, fatal disease with no cure.
  • A model global health academic partnership flourishes in Botswana July 06, 2026 The Botswana-UPenn Partnership has surpassed its goal of addressing HIV/AIDS and has broadened its scope to enhance national access to care and training.
  • AI framework aids target discovery for CAR T cell therapy June 24, 2026 The customizable, human-in-the-loop AI framework uses public data to find viable target antigens for CAR T cell therapy.
  • CAR T cell therapy leads to 10-year remissions in B-cell lymphoma patients June 23, 2026 Many patients with large B-cell lymphoma or follicular lymphoma were still living without a relapse, 10 years after receiving CAR T therapy.

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Featured Publications

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  • Magrolimab Plus Azacitidine Versus Placebo Plus Azacitidine in Patients With Untreated Higher-Risk Myelodysplastic Syndromes: The Phase III ENHANCE Study.
    Sallman DA, Garcia-Manero G, Daver N, Abboud CN, Stein E, Larkin K, Halpern AB, ... Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2026 Jul 13;:JCO2500617
  • Pharmacotherapeutic Decisions in Autism.
    Zisman-Ilani Y, Walfisch R, Veenstra-VanderWeele J, Mandell DS The New England journal of medicine. 2026 Jul 11
  • AI-predicted spatial transcriptomics unlocks breast cancer biomarkers from pathology.
    Shulman ED, Campagnolo EM, Lodha R, Chung Y, Stemmer A, Cantore T, Ru B, ... Cell. 2026 Jul 9;189(14):4225-4240.e25 Epub 2026 May 8
  • Setmelanotide for the Treatment of Acquired Hypothalamic Obesity.
    Miller JL, van Santen HM, Phillips SA, Hamilton J, Aberle J, Sathyapalan T, Mohamed Z, ... The New England journal of medicine. 2026 Jul 9;395(2):138-150
  • Challenges and future directions for multiple sclerosis after the 2024 McDonald diagnostic criteria.
    Oh J, Barkhof F, Bar-Or A, Ciccarrelli O, Coetzee T, Filippi M, Granziera C, ... Nature medicine. 2026 Jul 9

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Perelman School of Medicine
University of Pennsylvania
3400 Civic Center Boulevard
Building 421, Philadelphia, PA 19104

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