Perelman School of Medicine at the University of Pennsylvania

Robertson Lab

Publications: 2010-2013

For a list of all publications, access PubMed by click below

2010  ♦  2011  ♦  2012  ♦  2013
1 EBNA3C attenuates the function of p53 through interaction with inhibitor of growth family proteins 4 and 5. Saha A, Bamidele A, Murakami M, Robertson E.S.
2 Epstein-Barr Virus nuclear antigen 1 (EBNA1) confers resistance to apoptosis in EBV-positive B-lymphoma cells through up-regulation of surviving. Lu J, Murakami M, Verma SC, Cai Q, Haldar S, Kaul R, Wasik MA, Middeldorp J, Robertson E.S.
3 Ubiquitin/SUMO modification regulates VHL protein stability and nucleocytoplasmic localization. Cai Q., Robertson E.S.
4 Kaposi's sarcoma-associated herpesvirus inhibits interleukin-4-mediated STAT6 phosphorylation to regulate apoptosis and maintain latency. Cai Q., Verma S.C., Choi J.Y., Ma M, Robertson E.S.
5 Bub1 and CENP-F can contribute to Kaposi's sarcoma-associated herpesvirus genome persistence by targeting LANA to kinetochores. Xiao B, Verma SC, Cai Q, Kaul R, Lu J, Saha A, Robertson E.S.
6 Nm23-H1 can induce cell cycle arrest and apoptosis in B cells. Choudhuri T, Murakami M, Kaul R, Sahu SK, Mohanty S, Verma SC, Kumar P, Robertson E.S.
7 Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors.  Ohashi S, Natsuizaka M, Wong GS, Michaylira CZ, Grugan KD, Stairs DB, Kalabis J, Vega ME, Kalman RA, Nakagawa M, Klein-Szanto AJ, Herlyn M, Diehl JA, Rustgi AK, Nakagawa H.
8 Hypoxia inactivates the VHL tumor suppressor through PIASy-mediated SUMO modification. Cai Q, Verma SC, Kumar P, Ma M, Robertson E.S.
9 Multiple oncogenic viruses identified in Ocular surface squamous neoplasia in HIV-1 patients. Simbiri KO, Murakami M, Feldman M, Steenhoff AP, Nkomazana O, Bisson G, Robertson E.S.
10 Cellular corepressor TLE2 inhibits replication-and-transcription- activator-mediated transactivation and lytic reactivation of Kaposi's sarcoma-associated herpesvirus. He Z., Liu Y., Liang D., Wang Z., Robertson E.S., Lan K.

2011                                                                                                                                     ► Back to Top
1 Single-molecule analysis of replicated DNA reveals the usage of multiple KSHV genome regions for latent replication. Verma SC, Lu J, Cai Q, Kosiyatrakul S, McDowell ME, Schildkraut CL, Robertson E.S.
2 Epstein-Barr virus nuclear antigen 3C stabilizes Gemin3 to block p53-mediated apoptosis. Cai Q, Guo Y, Xiao B, Banerjee S, Saha A, Lu J, Glisovic T, Robertson E.S.
3 Functional modulation of the metastatic suppressor Nm23-H1 by oncogenic viruses. Saha A, Robertson E.S.
4 Upregulation of cellular Bcl-2 by the KSHV encoded RTA promotes virion production. Gao J, Cai Q, Lu J, Jha HC, Robertson E.S.
5 The single RBP-Jkappa site within the LANA promoter is crucial for establishing Kaposi's sarcoma-associated herpesvirus latency during primary infection. Lu J, Verma SC, Cai Q, Robertson E.S.
6 Kaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen reduces interleukin-8 expression in endothelial cells and impairs neutrophil chemotaxis by degrading nuclear p65. Li X, Liang D, Lin X, Robertson E.S., Lan K.
7 Survival of the fittest: a role for phage-encoded eukaryotic-like kinases. Robertson E.S.
8 Epstein-Barr virus-associated B-cell lymphomas: pathogenesis and clinical outcomes. Saha A, Robertson E.S.
9 Epstein-Barr virus nuclear antigen 3C facilitates G1-S transition by stabilizing and enhancing the function of cyclin D1. Saha A, Halder S, Upadhyay SK, Lu J, Kumar P, Murakami M, Cai Q, Robertson E.S.
10 miR-K12-7-5p encoded by Kaposi's sarcoma-associated herpesvirus stabilizes the latent state by targeting viral ORF50/RTA. Lin X, Liang D, He Z, Deng Q, Robertson E.S., Lan K.
11 The single RBP-Jkappa site within the LANA promoter is crucial for establishing Kaposi's sarcoma-associated herpesvirus latency during primary infection. Lu J, Verma S.C., Cai Q., Robertson E.S.

2012                                                                                                                                      ► Back to Top
1 Cytokine and Chemokine Expression Profiles in HIV-1 Infected Patients with Ocular Surface Squamous Neoplasia from Botswana.  Kenneth O. Simbiri, Hem C Jha, Richard D Dzeng, Giacomina Massaro-Giordano, Robertson  E.S.
2 Characterization of the OSSN Microbiome in HIV-1 Infected Patients.  Kenneth O. Simbiri, Robertson E.S.
3 Viral-associated trichodysplasia: characterization of a novel polyomavirus infection with therapeutic insights. Wanat KA, Holler PD, Dentchev T, Simbiri K, Robertson E, Seykora JT, Rosenbach M.
4 Evidence of an oncogenic gammaherpesvirus in domestic dogs. Huang SH, Kozak PJ, Kim J, Habineza-Ndikuyeze G, Meade C, Gaurnier-Hausser A, Patel R, Robertson E, Mason N.J.
5 Isolation and characterization of mouse and human esophageal epithelial cells in 3D organotypic culture. Kalabis J, Wong GS, Vega ME, Natsuizaka M, Robertson ES, Herlyn M, Nakagawa H, Rustgi AK.
6 Carboxyl-terminal amino acids 1052 to 1082 of the latency-associated nuclear antigen (LANA) interact with RBP-Jκ and are responsible for LANA-mediated RTA repression. Jin Y, He Z, Liang D, Zhang Q, Zhang H, Deng Q, Robertson ES, Lan K.
7 The RBP-Jκ binding sites within the RTA promoter regulate KSHV latent infection and cell proliferation. Lu J, Verma SC, Cai Q, Saha A, Dzeng RK, Robertson E.S.
8 Kaposi's sarcoma herpesvirus upregulates Aurora A expression to promote p53 phosphorylation and ubiquitylation. Cai Q, Xiao B, Si H, Cervini A, Gao J, Lu J, Upadhyay SK, Verma SC, Robertson E.S.
9 E2F1 mediated apoptosis induced by the DNA damage response is blocked by EBV nuclear antigen 3C in lymphoblastoid cells. Saha A, Lu J, Morizur L, Upadhyay SK, Aj MP, Robertson E.S.

2013                                                                                                                                     ► Back to Top
1 Comprehensive analysis of LANA interacting proteins essential for viral genome tethering and persistence. Verma S.C., Cai Q, Kreider E, Lu J, Robertson E.S.
2 A unique SUMO-2-interacting motif within LANA is essential for KSHV latency. Cai Q, Cai S, Zhu C, Verma SC, Choi JY, Robertson E.S.
3 IRF-4-mediated CIITA transcription is blocked by KSHV encoded LANA to inhibit MHC II presentation. Cai Q, Banerjee S, Cervini A, Lu J, Hislop AD, Dzeng R, Robertson E.S.
4 EBNA3C-mediated regulation of aurora kinase B contributes to Epstein-Barr virus-induced B-cell proliferation through modulation of the activities of the retinoblastoma protein and apoptotic caspases. Jha HC, Lu J, Saha A, Cai Q, Banerjee S, Prasad MA, Robertson E.S.
5 The EBV Latent Antigen 3C Inhibits Apoptosis through Targeted Regulation of Interferon Regulatory Factors 4 and 8.  Banerjee S, Lu J, Cai Q, Saha A, Jha HC, Dzeng RK, Robertson E.S.
6 H2AX phosphorylation is important for LANA-mediated Kaposi's sarcoma-associated herpesvirus episome persistence. Jha HC, Upadhyay SK, AJ Prasad M, Lu J, Cai Q, Saha A, Robertson E.S.