Second CHOP Experimental Pathology Faculty Retreat "MOLECULES, CELLS, ORGANS, ORGANISMS" | CHOP Commons @Cira Centre | December 12, 2024

We will be on the 12th Floor of the Cira Centre. Upon exiting the elevators, you will check in at the Welcome Center. All talks will be in the Multipurpose Room. Meals and social activities will take place in several adjacent areas.

Agenda

8:30 AM - 9:15 AM

Continental Breakfast

9:20 AM - 9:30 AM

Opening Remarks: Andrei Thomas-Tikhonenko, Director of Experimental Pathology

9:30 AM - 10 AM

RI Strategic Plan refresh: Susan Furth, EVP & Chief Scientific Officer

10:00 AM -12:00 PM

Session I: Molecules and Cells (Moderator: Matt Weitzman)

Priya Sivaramakrishnan

Transcription dynamics shaping worm embryonic fate patterning

Michael Marks

Surprising connections between ciliopathies and skin pigmentation

Janis Burkhardt

Mechanical control of T cell migration and activation

Melissa Gilbert (Guest Speaker | Division of Genomic Diagnostics)

Multiplexed Assays of Variant Effects: From bench to bedside

12:00 PM - 12:25 PM

Q&As with Department Chair: Bob Doms, CHOP Pathologist-in-Chief

12:30 PM - 1:30 PM

Lunch

1:30 PM - 3:30 PM

Session II: Cells and Organs (Moderator: Ike Eisenlohr)

Bo Li

Quantifiable blood TCR components associated with immune aging

Paula Oliver

Conflict resolution in the immune system

Andrew Wells

The genetics of immune tolerance & novel therapeutic targets

Margaret Chou

Developing Immunotherapeutics through the lens of cancer evolution

3:30 PM - 3:45 PM

Snack Break

3:45 PM - 5:15 PM

Session III: Organs and Organisms (Moderator: Andrei Thomas-Tikhonenko)

Leyuan Ma

Multiplex immune engineering to enhance gene and cell therapy

Wayne Hancock

Still Crazy About Tregs After All These Years

Stella Chou (Guest Speaker | Division of Hematology)

Precision Medicine for Transfusion Management of Sickle Cell Disease

5:15 PM - 6:30 PM

Cocktails and Conversations