Third CHOP Experimental Pathology Faculty Retreat "COLLABORATIVE SCIENCE" | CHOP Commons @Cira Centre | December 18, 2025
We will be on the 12th Floor of the Cira Centre. Upon exiting the elevators, you will check in at the Welcome Center. All talks will be in the Multipurpose Room. Meals and social activities will take place in several adjacent areas.
Agenda
8:30 AM - 9:15 AM
Continental Breakfast
9:15 AM - 9:30 AM
Opening Remarks: George Netto, Chair of Penn P&LM
9:30 AM - 10:10 AM
Eosinophilic Esophagitis: Mechanisms and Management (Moderator: Jan Burkhardt)
| Melanie Ruffner | CHOP Pediatrics/Allergy & Immunology |
| Paula Oliver | CHOP P&LM/Protective Immunity |
10:10 AM -10:50 PM
Liver fibrosis and dysbiosis in Fontan patients (Moderator: Will Bailis)
| Jack Rychik | CHOP Pediatrics/Cardiology |
| Liming Pei/Joe Zackular | CHOP P&LM/CMEM/Protective Immunity |
10:50 AM - 11:00 AM
Coffee Break
11:00 AM - 11:10 AM
Meet-and-greet with CHOP Innovation Ventures Leadership
Tom Wilton, Senior Vice President
11:10 AM - 11:50 PM
Engineered antibodies and their use in cancer immunotherapy (Moderator: Ike Eisenlohr)
| Andrei Thomas-Tikhonenko | CHOP P&LM/Cancer Pathobiology |
| Andrew Tsourkas | Penn SEAS |
11:50 AM - 12:30 PM
Mechanisms of resistance to immunotherapy (Moderator: Andrei Thomas-Tikhonenko)
| Evan Weber | CHOP Pediatrics/Oncology |
| Bo Li | CHOP P&LM/CCGM |
12:30 PM - 1:30 PM
Lunch
1:30 PM - 2:10 PM
Macrophage replacement therapies for metabolic diseases (Moderator: Jorge Henao-Mejia)
| Chris Bennett | CHOP Psychiatry |
| Will Bailis | CHOP P&LM/Protective Immunity |
2:10 PM - 2:50 PM
MHC class I- and class II-restricted antigens (Moderator: Andrew Wells)
| Jesper‌ Pallesen | Wistar Institute |
| Ike Eisenlohr | CHOP P&LM/Protective Immunity |
2:50 PM - 3:10 PM
Snack Break
3:10 PM - 3:50 PM
CRISPR screens to investigate RNA-binding proteins (Moderator: Peter Choi)
| Ophir Shalem | CHOP CCMT |
| Matt Weitzman | CHOP P&LM/Cancer Pathobiology |
3:50 PM - 4:30 PM
Collaboration and Community
| Joe Zackular (Discussion Leader) | CHOP P&LM/Protective Immunity |
| Jan Burkhardt (Discussion Leader) | CHOP P&LM/Cell Pathology |
4:30 PM - 6:00 PM