Selected Publications

Ding YY, Tasian SK: Agreeing to Agree: International Consensus Definitions of Complete Remission, Treatment Failure, and Relapse in Childhood Acute Lymphoblastic Leukemia. The Hematologist 19(6), November-December 2022.

Chen C, Yu W, Alikarami F, Qiu Q, Chen C-H, Flournoy J, Gao P, Uzun Y, Fang L, Hu Y, Zhu Q, Wang K, Libbrecht C, Felmeister A, Rozich I, Ding YY, Hunger SP, Wu H, Brown P, Guest EM, Barrett DM, Bernt KM, Tan K: Single-cell multi-omics reveals elevated plasticity and stem-cell-like blasts relevant to the poor prognosis of KMT2A-rearranged leukemia. Blood April 2022.

Ding Y, Loftus JP, Mathier B, Yu W, Hottman DA, He B, Falkenstein CD, Tasian SK, Tan K: Transcriptional Rewiring and Therapeutic Resistance in Philadelphia Chromosome-like Acute Lymphoblastic Leukemia. 64th ASH Annual Meeting and Exposition. Oral Presentation Paper 145, 2022.

Chen C, Xu J, Vincent T, Yu W, Ding Y, Chen CH, Kim S, Li E, Bandyopadhyay S, Pölönen P, Elsayed P, Newman H, Wood B, Hu J, Shraim R, Loh ML, Raetz E, Hunger SP, Pounds SB, Yang JJ, Mullighan CG, Frank D, Bernt KM, Teachey DT, Tan K.: Single-cell pan-cancer analysis reveals treatment resistance stem/progenitor-like subpopulation in the high-risk pediatric leukemia. Paper 531, Oral Presentation 64th ASH Annual Meeting and Exposition. 64th ASH Annual Meeting and Exposition. Oral Presentation Paper 531, 2022.

Xu J, Chen C, Vincent T, Pölönen P, Elsayed A, Hu J, Yoshimura S, Yu W, Chen C, Li E, Shraim R, Lavaert M, Newman H, Ding Y, Thadi A, Ahn KJ, Peng J, Gong C, Sun Y, Bandyopadhyay S, Frank D, Loh ML, Raetz E, Chen Z, Wood B, Devidas M, Dunsmore K, Winter S, Wu G, Bhandoola A, Pounds SB, Hunger SP, Yang JJ, Mullighan CG, Teachey DT, Tan K.: Progenitor sub-populations in treatment resistant T-ALL. 64th ASH Annual Meeting and Exposition. Oral Presentation Paper 717, 2022.

Ding YY, Kim H, Madden K, Loftus JP, Chen GM, Allen DH, Zhang R, Xu J, Hu Y, Tasian SK, Tan K. : Network Analysis Reveals Rational Combination Therapy Targets in Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia. Clin Cancer Res July 2021.

Chen GM, Chen C, Das RK, Gao P, Chen CH, Bandyopadhyay S, Ding YY, Uzun Y, Yu W, Zhu Q, Myers RM, Grupp SA, Barrett DM, Tan K.: Integrative bulk and single-cell profiling of pre-manufacture T-cell populations reveals factors mediating long-term persistence of CAR T-cell therapy. Cancer Discov April 2021.

Ding YY, Ramakrishna S, Long AH, et al.: Delayed cancer diagnoses and high mortality in children during the COVID-19 pandemic. Pediatr Blood Cancer June 2020.

He B, Gao P, Ding YY, Chen C, Chen GM, Chen C, Kim H, Tasian SK, Hunger SP, Tan K: Diverse noncoding mutations contribute to deregulation of cis-regulatory landscape in pediatric cancers. Science Advances June 2020.

Chen GM, Azzam A, Ding YY, Barrett DM, Grupp SA, Tan K. : Dissecting the tumor-immune landscape in chimeric antigen receptor T-cell therapy: key challenges and opportunities for a systems immunology approach. Clinical Cancer Research March 2020.