Kushol GuptaKushol Gupta is a Research Assistant Professor in the Department of Biochemistry & Biophysics at the Perelman School of Medicine of The University of Pennsylvania, a member of the BMB graduate group, and directs the Johnson Foundation Structural Biology and Biophysics Core, a departmental resource that serves Penn and the greater region. 

He is a structural biologist with expertise in both X-ray crystallography and solution biophysical methods, including small-angle X-ray and neutron scattering, light scattering, and analytical ultracentrifugation. His ongoing research focuses on retroviral integrases, their interaction with host factors, and a new class of drugs known as allosteric inhibitors of integrase (ALLINIs), which are potent antivirals against HIV. His research also includes other projects in the areas of phenylketonuria, RNA splicing, and site-specific recombination, highlighting the collaborative nature of research at Penn.


Penn Million Dollar Bike Ride/The Orphan Disease Center | Phenylketonuria | Feb 24th, 2022 | Youtube

Beckman-Coulter Webinars on Analytical Ultracentrifugation | Feb 5th 2021

Penn News Article | People and Places at Penn: Homecoming | November 3rd, 2021

Documentary | The Instrumental Chemist | August 4th, 2020

BMB Recruitment Trailer | November, 2020

Advanced Photon Source Small-angle Scattering Workshop Talks | BioSAXS 5 | November 5th, 2019

Wyatt Technologies Webinar | Applications of Light Scattering to HIV Integrase Structural Biology and Drug Discovery | September 3rd, 2018

ORNL Article | Two Steps Ahead: Neutrons Help Explore Future HIV Treatments | August 23rd 2018