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biochemistry and biophysics

little piece of scienceThe mission of the Department of Biochemistry and Biophysics at Penn Medicine is to promote and execute the highest quality research and education in the quantitative understanding of molecular mechanism in biology and medicine.

The Department is home to the largest concentration of expertise in modern quantitative biochemistry, biophysics and structural biology on campus – with faculty who are international leaders in these areas. The overarching goal of the Department is to use these disciplines to understand molecular mechanism in medicine and how to exploit this understanding for therapeutic purposes. Central to this mission is collaboration with other parts of the Penn research community. Ultimately, details of molecular mechanism underlie explanations of all disease processes and therapies. The Department of Biochemistry and Biophysics seeks to provide these explanations and to work with other scientists at Penn and elsewhere to exploit them in advancing biomedical research.

moleculeInsideThe faculty of the Department of Biochemistry and Biophysics hold many awards and honors. The Department has two members of the National Academy of Sciences (Englander and Dreyfuss), one Fellow of the Royal Society of London (Dutton), two HHMI Investigators (Dreyfuss and Van Duyne), and two Fellows of the Biophysical Society (Wand and Englander). Recent awards include: 2012 Christian R. and Mary F. Lindback Award for Distinguished Teaching (Lewis), 2012 Protein Society Dorothy Crowfoot Hodgkin Award (Lemmon), and Michael S. Brown New Investigator Award for 2012 (Shorter) and 2011 (Black).


Answer to Trivia Question



What neurotransmitter is thought to be the chemical responsible for maintaining mood balance?


B&B/BMB Retreat
November 20-21, 2014
Skytop Lodge gray line
PENNMedicine profiled Les Dutton in its Fall 2014 issue. The article entitled "Man of Many (P)arts" highlights his science and his artwork.gray line
Jeremy Wilusz's work describing how a cell “decides” to make circular RNAs was recently published in Genes and Development and highlighted on the Penn Medicine News Blog site. gray line
The Wand Lab has the cover story in the October 23, 2014 issue of Journal of Molecular Biology.
The article is entitled "Dynamic and thermodynamic response of the Ras protein Cdc42Hs upon association with the effector bomain of PAK3" and was authored by Veronica Moorman, Kathy Valentine, Sabrina Bédard, Vignesh Kasinath, Jakob Dogan, Fiona Love, and A. Joshua Wand. J. Mol. Biol. (2014) 426:3520–3538

2013 Trustees of the University of Pennsylvania