Publications

• Thrasher JG, Fagunloye AAG, Justiniano FS, Bernstein KA, Jensen RB. RAD51 Paralogs and RAD51 Paralog Complexes BCDX2 and CX3 Interact with BRCA2. BioRxiv [Preprint]. 2024 Oct 11:2024.10.10.617680.doi: 10.1101/2024.10.10.617680.

• Hengel SR, Oppenheimer K, Smith C, Schaich MA, Rein HL, Martino J, Darrah K, Ezekwenna O, Burton K, Van Houten B, Spies M, Bernstein KA. The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA. Nat Commun. 2024 Aug 21;15(1):7197. doi: 10.1038/s41467-024-51595-0.

• Rein HL, Bernstein KA. Variants in the first methionine of RAD51C are homologous recombination proficient due to an alternative start site. DNA Repair (Amst). 2024 Mar:135:103644.doi: 10.1016/j.dnarep.2024.103644. Epub 2024 Feb 1.

• Rein HL, Bernstein KA. Finding significance: New perspectives in variant classification of the RAD51 regulators, BRCA2 and beyond. DNA Repair (Amst). 2023 Oct:130:103563. doi: 10.1016/j.dnarep.2023.103563. Epub 2023 Aug 19.
• Luong TT, Li Z, Priedigkeit N, Parker PS, Böhm S, Rapchak K, Lee AV, Bernstein KA. Hrq1/RECQL4 regulation is critical for preventing aberrant recombination during DNA intrastrand crosslink repair and is upregulated in breast cancer. PLoS Genet. 2022 Sep 20;18(9):e1010122. doi: 10.1371/journal.pgen.1010122.

• Gambogi CW, Birchak GJ, Mer E, Brown DM, Yankson G, Kixmoeller K, Gavade JN, Espinoza JL, Kashyap P, Dupont CL, Logsdon GA, Heun P, Glass JI, Black BE. Efficient formation of single-copy human artificial chromosomes. Science 2024 Mar 22;383(6689):1344-1349. doi: 10.1126/science.adj3566. Epub 2024 Mar 21.

• Smith-Pillet ES, Billur R, Langelier M-F, Talele TT, Pascal JM, Black BE. A PARP2-specific active site α-helix melts to permit DNA damage-induced enzymatic activation. BioRxiv [Preprint]. 2024 May 20:2024.05.20.594972. doi: 10.1101/2024.05.20.594972.

• Bryan NW, Ali A, Niedzialkowska E, Mayne L, Stukenberg PT, Black BE. Structural basis for the phase separation of the chromosome passenger complex. Elife. 2024 Mar 8:13:e92709.doi: 10.7554/eLife.92709.

• Das A, Boese KG, Tachibana K, Baek SH, Lampson MA, Black BE. Centromere-specifying nucleosomes persist in aging mouse oocytes in the absence of nascent assembly. Curr Biol. 2023 Sep 11;33(17):3759-3765.e3. doi: 10.1016/j.cub.2023.07.032. Epub 2023 Aug 14.

• Tarasovetc EV, Allu PK, Wimbish RT, DeLuca JG, Cheeseman IM, Black BE, Grishchuk EL. Permitted and restricted steps of human kinetochore assembly in mitotic cell extracts. Mol Biol Cell. 2021 Jun 15;32(13):1241-1255.
• Pandey N and Black BE. Rapid Detection and Signaling of DNA Damage by PARP-1. Trends Biochem Sci 2021 Mar 2;S0968-0004(21)00028-1. doi: 10.1016/j.tibs.2021.01.014.
• Zandarashvili L, Langelier, M-F, Velagapudi UK, Hancock MA, Steffen JD, Billur R, Hannan ZM, Wicks AJ, Krastev DB, Pettitt SJ, Lord CJ, Talele TT, Pascal JM, Black BE. Structural basis for allosteric PARP-1 retention on DNA breaks. Science 2020 Apr 3;368(6486):eaax6367. Press release here.
• Logsdon, GL, Gambogi CW, Liskovykh MA, Barrey EJ, Larionov V, Miga KH, Heun P, and Black BE*. Human artificial chromosomes that bypass centromeric DNA. Cell, 178:624-639, 2019. (*corresponding author)
• Allu PK, Dawicki-McKenna JM, Van Eeuwen T, Slavin M, Braitbard M, Xu C, Kalisman N, Murakami K, Black BE. Structure of the Human Core Centromeric Nucleosome Complex. Curr Biol. 2019 Aug 19;29(16):2625-2639.e5.
• Barra V, Logsdon GA, Scelfo A, Hoffmann S, Hervé S, Aslanian A, Nechemia-Arbely Y, Cleveland DW, Black BE, Fachinetti D. Phosphorylation of CENP-A on serine 7 does not control centromere function. Nat Commun. 2019 Jan 11;10(1):175.
• Dawicki-McKenna JM, Black BE. Chromosomes: Keeping Centromeric Chromatin Tidy through S Phase. Curr Biol. 2019 Jan 7;29(1):R35-R37.
• Zasadzińska E, Huang J, Bailey AO, Guo LY, Lee NS, Srivastava S, Wong KA, French BT, Black BE, Foltz DR. Inheritance of CENP-A Nucleosomes during DNA Replication Requires HJURP. Dev Cell. 2018 Nov 5;47(3):348-362.e7.
• Logsdon GA, Black BE. The new normal of structure/function studies in the era of CRISPR/Cas9. Biochem J. 2018 May 15;475(9):1635-1642.
• Langelier MF, Zandarashvili L, Aguiar PM, Black BE, Pascal JM. NAD+ analog reveals PARP-1 substrate-blocking mechanism and allosteric communication from catalytic center to DNA-binding domains. Nat Commun. 2018 Feb 27;9(1):844.

• Grothusen GP, Chang R, Cao Z, Zhou N, Mittal M, Datta A, Wulfridge P, Beer T, Wang B, Zheng N, Tang HY, Sarma K, Greenberg RA, Shi J, Busino L. DCAF15 control of cohesin dynamics sustains acute myeloid leukemia. Nat Commun. 2024 Jul 3;15(1):5604.doi: 10.1038/s41467-024-49882-x.

• Islam S, Gour J, Beer T, Tang HY, Cassel J, Salvino JM, Busino L. A Tandem-Affinity Purification Method for Identification of Primary Intracellular Drug-Binding Proteins. ACS Chem Biol. 2024 Feb 16;19(2):233-242.doi: 10.1021/acschembio.3c00570. Epub 2024 Jan 25.

• Zhou N, Busino L. Targeting epigenetics and ferroptosis in DLBCL. Blood. 2023 Sep 28;142(13):1108-1109. doi: 10.1182/blood.2023021310.

• Zhou N, Choi J, Grothusen G, Kim BJ, Ren D, Cao Z, Liu Y, Li Q, Inamdar A, Beer T, Tang HY, Perkey E, Maillard I, Bonasio R, Shi J, Ruella M, Wan L, Busino L. DLBCL-associated NOTCH2 mutations escape ubiquitin-dependent degradation and promote chemoresistance. Blood. 2023 Sep 14;142(11):973-988.doi: 10.1182/blood.2022018752.

Sannigrahi MK, Raghav L, Diab A, Basu D. The imprint of viral oncoproteins on the variable clinical behavior among human papilloma virus-related oropharyngeal squamous cell carcinomas. Tumour Virus Res. 2024 Nov 1:18:200295. doi: 10.1016/j.tvr.2024.200295. Online ahead of print.

• Dooling LJ, Anlaş AA, Tobin MP, Ontko NM, Marchena T, Wang M, Andrechak JC, Discher DE. Clustered macrophages cooperate to eliminate tumors via coordinated intrudopodia. bioRxiv [Preprint]. 2024 Sep 20:2024.09.19.613918.doi: 10.1101/2024.09.19.613918.

• Hayes BH, Wang M, Zhu H, Phan SH, Dooling LJ, Andrechak JC, Chang AH, Tobin MP, Ontko NM, Marchena T, Discher DE. Chromosomal instability can favor macrophage-mediated immune response and induce a broad, vaccination-like anti-tumor IgG response. Elife. 2024 May 28:12:RP88054.doi: 10.7554/eLife.88054.
• Wang M, Phan S, Hayes BH, Discher DE. Genetic heterogeneity in p53-null leukemia increases transiently with spindle assembly checkpoint inhibition and is not rescued by p53. Chromosoma 2024 Jan;133(1):77-92.doi: 10.1007/s00412-023-00800-y. Epub 2023 May 31.

• Tobin MP, Pfeifer CR, Zhu PK, Hayes BH, Wang M, Vashisth M, Xia Y, Phan SH, Belt SA, Irianto J, Discher DE. Differences in cell shape, motility, and growth reflect chromosomal number variations that can be visualized with live-cell ChReporters. Mol Biol Cell. 2023 Dec 1;34(13):br19.doi: 10.1091/mbc.E23-06-0207. Epub 2023 Oct 30.

• Saini K, Cho S, Tewari M, Jalil AR, Wang M, Kasznel AJ, Yamamoto K, Chenoweth DM, Discher DE. Pan-tissue scaling of stiffness versus fibrillar collagen reflects contractility-driven strain that inhibits fibril degradation. bioRxiv [Preprint]. 2023 Sep 28:2023.09.27.559759.doi: 10.1101/2023.09.27.559759.

• Hayes BH, Zhu H, Andrechak JC, Dooling LJ, Discher DE. Titrating CD47 by mismatch CRISPR-interference reveals incomplete repression can eliminate IgG-opsonized tumors but limits induction of antitumor IgG.

  PNAS Nexus. 2023 Jul 27;2(8):pgad243.doi: 10.1093/pnasnexus/pgad243. eCollection 2023 Aug.

• Hayes BH, Zhu PK, Wang M, Pfeifer CR, Xia Y, Phan S, Andrechak JC, Du J, Tobin MP, Anlas A, Dooling LJ, Vashisth M, Irianto J, Lampson MA, Discher DE. Confinement plus myosin-II suppression maximizes heritable loss of chromosomes, as revealed by live-cell ChReporters. J Cell Sci. 2023 Jun 1;136(11):jcs260753.doi: 10.1242/jcs.260753. Epub 2023 Jun 8.
• Dooling LJ, Andrechak JC, Hayes BH, Kadu S, Zhang W, Pan R, Vashisth M, Irianto J, Alvey CM, Ma L, Discher DE. Cooperative phagocytosis of solid tumours by macrophages triggers durable anti-tumour responses.

  Nat Biomed Eng. 2023 Sep;7(9):1081-1096.doi: 10.1038/s41551-023-01031-3. Epub 2023 Apr 24.

• Dooling LJ, Saini K, Anlaş AA, Discher DE. Tissue mechanics coevolves with fibrillar matrisomes in healthy and fibrotic tissues. Matrix Biol. 2022 Aug:111:153-188. doi: 10.1016/j.matbio.2022.06.006. Epub 2022 Jun 25.

• Wang M, Ivanovska I, Vashisth M, Discher DE. Nuclear mechanoprotection: From tissue atlases as blueprints to distinctive regulation of nuclear lamins. APL Bioeng. 2022 Jun 15;6(2):021504. doi: 10.1063/5.0080392. eCollection 2022 Jun.
• Andrechak JC, Dooling LJ, Tobin MP, Zhang W, Hayes BH, Lee JY, Jin X, Irianto J, Discher DE. CD47-SIRPα Checkpoint Disruption in Metastases Requires Tumor-Targeting Antibody for Molecular and Engineered Macrophage Therapies. Cancers (Basel). 2022 Apr 11;14(8):1930.doi: 10.3390/cancers14081930.
• Jalil AR, Tobin MP, Discher DE. Suppressing or Enhancing Macrophage Engulfment through the Use of CD47 and Related Peptides. Bioconjug Chem. 2022 Nov 16;33(11):1989-1995. doi: 10.1021/acs.bioconjchem.2c00019. Epub 2022 Mar 22.
• Pfeifer CR, Tobin MP, Cho S, Vashisth M, Dooling LJ, Vazquez LL, Ricci-De Lucca EG, Simon KT, Discher DE. Gaussian curvature dilutes the nuclear lamina, favoring nuclear rupture, especially at high strain rate. Nucleus. 2022 Dec;13(1):129-143.doi: 10.1080/19491034.2022.2045726.
• Jalil AR, Andrechak JC, Hayes BH, Chenoweth DM, Discher DE. Human CD47-Derived Cyclic Peptides Enhance Engulfment of mAb-Targeted Melanoma by Primary Macrophages. Bioconjug Chem. 2022 Nov 16;33(11):1973-1982.doi: 10.1021/acs.bioconjchem.2c00020. Epub 2022 Mar 14.
• Vashisth M, Cho S, Irianto J, Xia Y, Wang M, Hayes B, Wieland D, Wells R, Jafarpour F, Liu A, Discher DE. Scaling concepts in 'omics: Nuclear lamin-B scales with tumor growth and often predicts poor prognosis, unlike fibrosis. Proc Natl Acad Sci U S A. 2021 Nov 30;118(48):e2112940118.doi: 10.1073/pnas.2112940118.
• Jalil AR, Hayes BH, Andrechak JC, Xia Y, Chenoweth DM, Discher DE. Multivalent, Soluble Nano-Self Peptides Increase Phagocytosis of Antibody-Opsonized Targets while Suppressing "Self" Signaling. ACS Nano. 2020 Nov 24;14(11):15083-15093. doi: 10.1021/acsnano.0c05091. Epub 2020 Nov 13.

• Hayes BH, Tsai RK, Dooling LJ, Kadu S, Lee JY, Pantano D, Rodriguez PL, Subramanian S, Shin JW, Discher DE. Macrophages show higher levels of engulfment after disruption of cis interactions between CD47 and the checkpoint receptor SIRPα. J Cell Sci. 2020 Mar 6;133(5):jcs237800. doi: 10.1242/jcs.237800.

• Xia Y#, Pfeifer CR#, Zhu K, Irianto J, Liu D, Pannell K, Chen EJ, Dooling LJ, Tobin MP, Wang M, Ivanovska IL, Smith LR, Greenberg RA, Discher DE. Rescue of DNA damage after constricted migration reveals a mechano-regulated threshold for cell cycle. J Cell Biol. 2019 Aug 5;218(8):2545-2563. #Contributed Equally.
• Discher DE. From DNA damage to epithelial integrity: new roles for cell forces. Mol Biol Cell. 2019 Jul 22;30(16):1879-1881.
• Xia Y, Ivanovska IL, Zhu K, Smith L, Irianto J, Pfeifer CR, Alvey CM, Ji J, Liu D, Cho S, Bennett RR, Liu AJ, Greenberg RA, Discher DE. Nuclear rupture at sites of high curvature compromises retention of DNA repair factors. J Cell Biol. 2018 Nov 5;217(11):3796-3808.
• Smith LR, Irianto J, Xia Y, Pfeifer CR, Discher DE. Constricted migration modulates stem cell differentiation. Mol Biol Cell. 2019 Jul 22;30(16):1985-1999.
• Pfeifer CR, Xia Y, Zhu K, Liu D, Irianto J, García VMM, Millán LMS, Niese B, Harding S, Deviri D, Greenberg RA, Discher DE. Constricted migration increases DNA damage and independently represses cell cycle. Mol Biol Cell. 2018 Aug 8;29(16):1948-1962.
• Irianto J, Xia Y, Pfeifer CR, Athirasala A, Ji J, Alvey C, Tewari M, Bennett RR, Harding SM, Liu AJ, Greenberg RA, Discher DE. DNA Damage Follows Repair Factor Depletion and Portends Genome Variation in Cancer Cells after Pore Migration. Curr Biol. 2017 Jan 23;27(2):210-223.
• Cho S, Irianto J, Discher DE. Mechanosensing by the nucleus: From pathways to scaling relationships. J Cell Biol. 2017 Feb;216(2):305-315.
• Irianto J, Pfeifer CR, Xia Y, Discher DE. SnapShot: Mechanosensing Matrix. Cell. 2016 Jun 16;165(7):1820-1820.e1.

• Welles RM, Sojitra KA, Garabedian MV, Xia B, Wang W, Guan M, Regy RM, Gallagher ER, Hammer DA, Mittal J, Good MC. Determinants that enable disordered protein assembly into discrete condensed phases. Nat Chem. 2024 Jul;16(7):1062-1072. doi: 10.1038/s41557-023-01423-7. Epub 2024 Feb 5.

• Qian W, Good MC. Peeking under the hood of early embryogenesis: Using tools and synthetic biology to understand native control systems and sculpt tissues. Semin Cell Dev Biol. 2023 May 30:141:43-49. doi: 10.1016/j.semcdb.2022.04.016. Epub 2022 May 5.

• Garabedian MV, Su Z, Dabdoub J, Tong M, Deiters A, Hammer DA, Good MC. Protein Condensate Formation via Controlled Multimerization of Intrinsically Disordered Sequences. Biochemistry. 2022 Nov 15;61(22):2470-2481. doi: 10.1021/acs.biochem.2c00250. Epub 2022 Aug 2.

• Chen H, Good MC. Nascent transcriptome reveals orchestration of zygotic genome activation in early embryogenesis. Curr Biol. 2022 Oct 10;32(19):4314-4324.e7. doi: 10.1016/j.cub.2022.07.078. Epub 2022 Aug 24.

• Sandlin CW, Gu S, Xu J, Deshpande C, Feldman MD, Good MC. Epithelial cell size dysregulation in human lung adenocarcinoma. PLoS One. 2022 Oct 6;17(10):e0274091. doi: 10.1371/journal.pone.0274091. eCollection 2022.

• Guan M, Garabedian MV, Leutenegger M, Schuster BS, Good MC, Hammer DA. Incorporation and Assembly of a Light-Emitting Enzymatic Reaction into Model Protein Condensates. Biochemistry 2021 Oct 26;60(42):3137-3151. doi: 10.1021/acs.biochem.1c00373. Epub 2021 Oct 14.

• Garabedian MV, Wang W, Dabdoub JB, Tong M, Caldwell RM, Benman W, Schuster BS, Deiters A, Good MC. Designer membraneless organelles sequester native factors for control of cell behavior. Nat Chem Biol. 2021 Sep;17(9):998-1007. doi: 10.1038/s41589-021-00840-4. Epub 2021 Aug 2.

• Bermudez JG, Deiters A, Good MC. Patterning Microtubule Network Organization Reshapes Cell-Like Compartments. ACS Synth Biol. 2021 Jun 18;10(6):1338-1350. doi: 10.1021/acssynbio.0c00575. Epub 2021 May 14.

• Jiang H*, Zhang T*, Kaur H, Shi T, Krishnan A, Kwon Y, Sung P, Greenberg RA. BLM helicase unwinds lagging strand substrates to assemble the ALT telomere damage response. Molecular Cell 2024 May 2;84(9):1684-1698.e9. doi: 10.1016/j.molcel.2024.03.011. Epub 2024 Apr 8. *Co-First Authors; featured on the cover
• Krishnamoorthy V, Foglizzo M, Dilley RL, Wu A, Datta A, Dutta P, Campbell LJ, Degtjarik O, Musgrove LJ, Calabrese AN, Zeqiraj E, Greenberg RA. The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity. Cell 2024 Mar 22;S0092-8674(24)00250-2.doi: 10.1016/j.cell.2024.03.002. Online ahead of print.
• Zhang T, Rawal Y, Jiang H, Kwon Y, Sung P, Greenberg RA. Break-Induced Replication Orchestrates resection dependent template switching. Nature June 2023. Online ahead of print.
• Jiang Q, Foglizzo M, Morozov YI, Yang X, Datta A, Tian L, Thada V, Li W, Zeqiraj E, Greenberg RA. Autologous K63 deubiquitylation within the BRCA1-A complex licenses DNA damage recognition. J Cell Biol. 2022 Sep 5;221(9):e202111050.
• Verma P, Greenberg RA. Communication between chromatin and homologous recombination. Curr Opin Genet Dev. 2021 Jun 4;71:1-9.
• Vessoni AT, Zhang T, Quinet A, Jeong H-C, Munroe M, Wood M, Tedone E, Vindigni A, Shay JW, Greenberg RA, Batista L FZ. Telomere erosion in human pluripotent stem cells leads to ATR-mediated mitotic catastrophe. J Cell Biol. 2021 Jun 7;220(6):e202011014.
• Lippert TP, Greenberg RA. The abscopal effect: a sense of DNA damage is in the air. J Clin Invest. 2021 May 3;131(9):e148274.
• Jiang H and Greenberg RA. Morning for Irofulven; What could be fiNER? Clinical Cancer Research 2021 Apr 1;27(7):1833-1835. doi: 10.1158/1078-0432.CCR-20-4708.
• Verma P, Zhou Y, Cao Z, Deraska PV, Deb M, Arai E, Li W, Shao Y, Puentes L, Li Y, Patanka S, Mach RH, Faryabi RB, Shi J*, Greenberg RA*. ALC1 links chromatin accessibility to PARP inhibitor response in homologous recombination-deficient cells. Nat Cell Biol. 2021 Jan 18. Notes: *co-corresponding authors doi: 10.1038/s41556-020-00624-3.
• Jalil AAR, Hayes BH, Andrechak JC, Xia Y, Chenoweth DM, Discher DE. Multivalent, Soluble Nano-Self Peptides Increase Phagocytosis of Antibody-Opsonized Targets while Suppressing "Self" Signaling. ACS Nano 2020 Nov 24;14(11):15083-15093. doi: 10.1021/acsnano.0c05091. Epub 2020 Nov 13.
• Chen J, Harding SM, Natesan R, Tian L, Benci JL, Li W, Minn AJ, Asangani IA, Greenberg RA. Cell Cycle Checkpoints Cooperate to Suppress DNA- and RNA-Associated Molecular Pattern Recognition and Anti-Tumor Immune Responses. Cell Rep. 2020 Sep 1;32(9):108080.
• Walden M*, Tian L*, Ross R, Sykora UM, Byrne DP, Hesketh EL, Masandi SK, Cassel J, Geirge R, Ault JR, Oualid FE, Pawlowski K, Salvino JM, Eyers PA, Ranson NA, Del Galdo F, Greenberg RA#, Zeqiraj E#. Metabolic control of BRISC-SHMT2 complex assembly regulates immune signaling. Nature Jun;570(7760):194-199 2019. Notes: *co-first authors and # co-corresponding authors
• Verma P, Dilley RL, Zhang T, Gyparaki MT, Li Y, Greenberg RA. RAD52 and SLX4 act nonepistatically to ensure telomere stability during alternative telomere lengthening. Genes Dev. 2019 Feb 1;33(3-4):221-235.
• Greenberg RA. Assembling a protective shield. Nat Cell Biol. 2018 Aug;20(8):862-863.
• Li ML, Jiang Q, Bhanu NV, Wu J, Li W, Garcia BA, Greenberg RA. Phosphorylation of TIP60 Suppresses 53BP1 Localization at DNA Damage Sites. Mol Cell Biol. 2018 Dec 11;39(1). pii: e00209-18.
• Harding SM, Benci JL, Irianto J, Discher DE, Minn AJ, Greenberg RA. Mitotic progression following DNA damage enables pattern recognition within micronuclei. Nature 2017 Aug 24;548(7668):466-470.
• Dilley RL, Verma P, Cho NW, Winters HD, Wondisford AR, Greenberg RA. Break-induced telomere synthesis underlies alternative telomere maintenance. Nature 2016 Nov 3;539(7627):54-58. Notes: Comment in Nature: DNA Repair: Telomere-lengthening mechanism revealed. Roake CM, Artandi SE. Nature 2016 Oct 19. doi: 10.1038/nature19483.
• Cho NW, Dilley RL, Lampson MA, Greenberg RA. Interchromosomal homology searches drive directional ALT telomere movement and synapsis. Cell 2014 Sep 25;159(1):108-121.
• Sawyer SL, Tian L, Kähkönen M, Schwartzentruber J, Kircher M; University of Washington Centre for Mendelian Genomics; FORGE Canada Consortium, Majewski J, Dyment DA, Innes AM, Boycott KM, Moreau LA, Moilanen JS, Greenberg RA. Biallelic mutations in BRCA1 cause a new Fanconi anemia subtype. Cancer Discov. 2015 Feb;5(2):135-42.
• Verma P, Greenberg RA. Noncanonical views of homology-directed DNA repair. Genes Dev. 2016 May 15;30(10):1138-54.
• Sobhian B, Shao G, Lilli DR, Culhane AC, Moreau LA, Xia B, Livingston DM, Greenberg RA. RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites. Science 2007 May 25;316(5828):1198-202.
• Shao G, Patterson-Fortin J, Messick TE, Feng D, Shanbhag N, Wang Y, Greenberg RA. MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaks. Genes Dev. 2009 Mar 15;23(6):740-54.
• Shanbhag NM, Rafalska-Metcalf IU, Balane-Bolivar C, Janicki SM, Greenberg RA. ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks. Cell 2010 Jun 11;141(6):970-81.
• Greenberg RA. BRCA1, Everything but the ring? Science 2011 Oct 28;334(6055):459-60.
• Tang J, Cho NW, Cui G, Manion EM, Shanbhag NM, Botuyan MV, Mer G, Greenberg RA. Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination. Nat Struct Mol Biol. 2013 Mar;20(3):317-25.
• Zheng H#, Gupta V#, Patterson-Fortin J#, Bhattacharya S#, Katlinski K, Wu J, Varghese B, Carbone CJ, Aressy B, Fuchs SY*, Greenberg RA*. A BRISC-SHMT complex deubiquitinates IFNAR1 and regulates interferon responses. Cell Rep. 2013 Oct 17;5(1):180-93. Notes: # co-first author * co-corresponding author.
• Cho NW, Greenberg RA. DNA repair: Familiar ends with alternative endings. Nature 2015 Feb 12;518(7538):174-6.
• Zeqiraj E, Tian L, Piggott CA, Pillon MC, Duffy NM, Ceccarelli DF, Keszei AF, Lorenzen K, Kurinov I, Orlicky S, Gish GD, Heck AJ, Guarné A, Greenberg RA*, Sicheri F*. Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function. Mol Cell 2015 Sep 17;59(6):970-83. Notes: *co-corresponding authorship.
• Jiang Q, Paramasivam M, Aressy B, Wu J, Bellani M, Tong W, Seidman MM, Greenberg RA. MERIT40 cooperates with BRCA2 to resolve DNA interstrand cross-links. Genes Dev. 2015 Sep 15;29(18):1955-68.

• Folkert IW, Molina Arocho WA, To TKJ, Devalaraja S, Molina IS, Shoush J, Mohei H, Zhai L, Akhtar MN, Kochat V, Arslan E, Lazar AJ, Wani K, Israel WP, Zhang Z, Chaluvadi VS, Norgard RJ, Liu Y, Fuller AM, Dang MT, Roses RE, Karakousis GC, Miura JT, Fraker DL, Eisinger-Mathason TSK, Simon MC, Weber K, Tan K, Fan Y, Rai K, Haldar M. An iron-rich subset of macrophages promotes tumor growth through a Bach1-Ednrb axis. J Exp Med. 2024 Oct 7;221(10):e20230420. doi: 10.1084/jem.20230420. Epub 2024 Sep 30.
• Lobel GP, Han N, Arocho WAM, Silber M, Shoush J, Noji MC, Jerrick To TK, Zhai L, Lesner NP, Simon MC, Haldar M. Glutamine availability regulates cDC subsets in tissue. bioRxiv [Preprint]. 2024 Sep 21:2024.09.17.613574.doi: 10.1101/2024.09.17.613574
• Yu P, Cao S, Yang SM, Rai G, Martinez NJ, Yasgar A, Zakharov AV, Simeonov A, Molina Arocho WA, Lobel GP, Mohei H, Scott AL, Zhai L, Furth EE, Simon MC, Haldar M. RALDH1 Inhibition Shows Immunotherapeutic Efficacy in Hepatocellular Carcinoma. Cancer Immunol Res. 2024 Feb 2;12(2):180-194. doi: 10.1158/2326-6066.CIR-22-1023.
• Dang MT, Mafra F, Haldar M. Isolation of myeloid cells from mouse brain tumors for single-cell RNA-seq analysis. STAR Protoc. 2021 Nov 17;2(4):100957. doi: 10.1016/j.xpro.2021.100957. eCollection 2021 Dec 17.

• Dang MT, Gonzalez MV, Gaonkar KS, Rathi KS, Young P, Arif S, Zhai L, Alam Z, Devalaraja S, To TKJ, Folkert IW, Raman P, Rokita JL, Martinez D, Taroni JN, Shapiro JA, Greene CS, Savonen C, Mafra F, Hakonarson H, Curran T, Haldar M. Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality. Cell Rep. 2021 Mar 30;34(13):108917. doi: 10.1016/j.celrep.2021.108917.

• Lamelza P, Parrado M, Hamlin E, Lampson MA. Species-specific satellite DNA composition dictates de novo formation of PRC1-mediated pericentric heterochromatin. bioRxiv [Preprint]. 2024 Oct 13:2024.10.11.617947. doi: 10.1101/2024.10.11.617947.

• Clark FE, Greenberg NL, Silva DMZA, Trimm E, Skinner M, Walton RZ, Rosin LF, Lampson MA, Akera T. An egg-sabotaging mechanism drives non-Mendelian transmission in mice. Curr Biol. 2024 Sep 9;34(17):3845-3854.e4. doi: 10.1016/j.cub.2024.07.001. Epub 2024 Jul 26.

• Chen GY, Deng C, Chenoweth DM, Lampson MA. The central spindle drives anaphase chromosome segregation. bioRxiv [Preprint]. 2024 Aug 30:2024.08.30.610502. doi: 10.1101/2024.08.30.610502.

• Jeon HJ, Levine MT, Lampson MA. Telomere Elongation During Pre-Implantation Embryo Development. Adv Anat Embryol Cell Biol. 2024:238:121-129. doi: 10.1007/978-3-031-55163-5_6.

• Das A, Boese KG, Tachibana K, Baek SH, Lampson MA, Black BE. Centromere-specifying nucleosomes persist in aging mouse oocytes in the absence of nascent assembly. Curr Biol. 2023 Sep 11;33(17):3759-3765.e3. doi: 10.1016/j.cub.2023.07.032. Epub 2023 Aug 14.

• Dudka D, Akins RB, Lampson MA. FREEDA: An automated computational pipeline guides experimental testing of protein innovation. J Cell Biol. 2023 Sep 4;222(9):e202212084. doi: 10.1083/jcb.202212084. Epub 2023 Jun 26.

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