UPHS High Sensitivity Troponin Algorithms

 
HUP Spruce
HUP Cedar
PPMC
PAH
MCP/PMPH
CCH
Emergency Department
Troponin T Troponin I Troponin T Troponin T Troponin I

Troponin I

Inpatient
Troponin T Troponin I Troponin T Troponin T Troponin I

Troponin I

Project Updates:

  • ​​​​​​All entities are live as of March 1, 2023​​​​​​
  • Starting on June 2, 2022, all UPHS Troponin measurements will be performed with a high sensitivity assay.

Important change:  

Collection will be a Green top tube (Lithium heparin, dark or light green). Troponin interpretations are changing significantly.

► For tip sheets, training materials, etc, please see penncvd.org/tn

Team

Bierl, Charlene

Physician
 charlene.bierl@pennmedicine.upenn.edu

Lubin, Joshua T

CAO Precision Medicine
 joshua.lubin@pennmedicine.upenn.edu

Project Acknowledgements & Evidence Base

Keith Hemmert, Andrew Albert, Scott Livingston, Ryan Keenan, Sean Foster, Dheeraj Duggineni, Katya De Souza, Dana Liu, Thomas Kramer, Joseph Portale, Peter Cridge, Regan Tuder, Ping Wang, Charlene Bierl, Amy Tojino, Anna Moran, Michael Atweh, Michael Husson, Roseann Gaultieri , Charlene Bierl, Maureen Manzoni, Elliot Krauss, James Heald, Christina Pierre, Jay Giri, Dan Kolansky, Sri Adusumalli, Gene Chang, Brian Drachman, Colin Craft, Douglas Jacoby, Desiree Younes, Sameh Saleh, Claiborne Childes, Judd Flesch, Esme Singer, Joel Betesh, Jasmeet Bajaj, Brooke McDonnell, Josh Lubin, Penny Martin, Jeff Landgraf, Ceasar Bautista, Mika Epps, Vivek Ahya, Ilona Lorincz, Hisham Valiuddin, Samantha Powers, Christopher Rymer, Nancy Huynh, Nancy Vinca (VA), Narek Israelyan, Deneen Spatz

 

"High Sensitivity cardiac troponins are the preferred standard for establishing a biomarker diagnosis for acute myocardial infarction, allowing for more accurate detection and exclusion of Myocardial Injury"  

2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines | Circulation