Charles A. Stanley, M.D.
Emeritus Professor CE of Pediatrics (Endocrinology and Diabetes)
Senior Physician, Endocrine/Diabetes, Children's Hospital of Philadelphia
Department: Pediatrics
Contact information
Children's Hospital of Philadelphia
34th Street & Civic Center Blvd
Philadelphia, PA 19104
34th Street & Civic Center Blvd
Philadelphia, PA 19104
Office: 2155903420
Fax: 2155903053
Fax: 2155903053
Email:
stanleyc@email.chop.edu
stanleyc@email.chop.edu
Publications
Education:
B.A. (Biochemical Sciences)
Harvard University, 1964.
M.D. (Medicine)
University of Virginia School of Medicine, 1970.
Permanent linkB.A. (Biochemical Sciences)
Harvard University, 1964.
M.D. (Medicine)
University of Virginia School of Medicine, 1970.
Description of Research Expertise
genetic disorders of carbohydrate and fatty acid metabolism, insulin secretionDescription of Clinical Expertise
hypoglycemia, glycogenoses, fatty acid oxidation disorders, diabetes mellitusSelected Publications
Zhang T, Chen P, Stanley CA, Hoshi T, Li C.: Mechanisms of octanoic acid potentiation of insulin secretion in isolated islets. Islets 8: 8 - 12, Mar 2019.Katheryn Grand, Christina Gonzalez-Gandolfi, Amanda Ackerman, Deema Aljeaid, Emma Bedoukian, Lynne M. Bird, Diva DeLeón, Jullianne Diaz, Robert J.Hopkin, Sejal P. Kadakia, Beth Keena, Karen O. Klein, Ian Krantz, Eyby Leon, Katherine Lord, Carey McDougall, Livija Medne, Cara M. Skraban, Charles A. Stanley, Jennifer Tarpinian, Elaine Zackai, Matthew A. Deardorff, Jennifer M. Kalish: Hyperinsulinemic Hypoglycemia in Six Patients with de novo NSD1 Mutations. Am J Medical Genetics 2019 Notes: (in press).
Adzick NS, De Leon DD, States LJ, Lord K, Bhatt TR, Becker SA, Stanley CA: Surgical treatment of congenital hyperinsulinism: Results from 500 pancreatectomies in neonates and children. J Ped Surg 54: 27-32, 2019.
Nassar OM, Li C, Stanley CA, Pettitt BM, Smith TJ: Glutamate dehydrogenase: Structure of a hyperinsulinism mutant, corrections to the atomic model, and insights into a regulatory site. Proteins 87(1): 41-50, Nov 2018.
Adzick NS, De Leon DD, States LJ, Lord K, Bhatti TR, Becker SA, Stanley CA.: Surgical treatment of congenital hyperinsulinism: Results from 500 pancreatectomies in neonates and children. J Pediatr Surg Page: https://doi.org/10.1016/j.jpedsurg.2018.10.030, Oct 2018 Notes: jpedsurg.2018.10.030. [Epub ahead of print]
Tung JY, Boodhansingh K, Stanley CA, De Leon DD: Clinical heterogeneity of hyperinsulinism due to HNF1A and HNF4A mutations. Pediatr Diabetes 19(5): 910-916, Aug 2018.
Srivastava S, Li Z, Soomro I, Sun Y, Wang J, Bao L, Coetzee WA, Stanley CA, Li C, Skolnik EY: Regulation of KATP Channel Trafficking in Pancreatic β Cells by Protein Histidine Phosphorylation. Diabetes Feb 12 2018 Notes: [Epub ahead of print]
Changhong Li, Amanda M. Ackermann, Kara E. Boodhansingh, Tricia R. Bhatti, Chengyang Liu, Jonathan Schug, Nicolai Doliba, Bing Han, Karen E. Cosgrove, Indraneel Banerjee, Franz M. Matschinsky, Itzhak Nissim, Klaus H. Kaestner, Ali Naji, N. Scott Adzick, Mark J. Dunne, Charles A. Stanley and Diva D. De León: Functional and Metabolomic Consequences of ATP-dependent Potassium Channel Inactivation in Human Islets. Diabetes [Epub ahead of print], April 25 2017.
Barrosse-Antle M, Su C, Chen P, Boodhansingh KE, Smith TJ, Stanley CA, De León DD, Li C: A severe case of hyperinsulinism due to hemizygous activating mutation of glutamate dehydrogenase. Pediatric Diabetes Feb 6 (on-line) 2017.
Boodhansingh K, Ferrara C, Stanley CA, et al: Novel Hypoglycemia Phenotype in Congenital Hyperinsulinism Due to Dominant Mutations of Uncoupling Protein 2 (UCP2). The Journal of Clinical Endocrinology & Metabolism Jan 2017 Notes: Accepted for publication.