Ari Borthakur, PhD
Adjunct Professor of Radiology
Associate Director, Center for Magnetic Resonance & Optical Imaging, University of Pennsylvania, Philadelphia, PA
Department: Radiology
Contact information
Center for Magnetic Resonance & Optical Imaging
University of Pennsylvania
B1 Stellar-Chance Labs
422 Curie Blvd.
Philadelphia, PA 19104
University of Pennsylvania
B1 Stellar-Chance Labs
422 Curie Blvd.
Philadelphia, PA 19104
Office: (215) 573-8482
Fax: (215) 573-2113
Fax: (215) 573-2113
Email:
borthaku@upenn.edu
borthaku@upenn.edu
Publications
Education:
BS (Physics)
Angelo State University, San Angelo, TX, 1994.
PhD (Biophysics)
University of Pennsylvania, Philadelphia, PA, 2000.
Permanent linkBS (Physics)
Angelo State University, San Angelo, TX, 1994.
PhD (Biophysics)
University of Pennsylvania, Philadelphia, PA, 2000.
Description of Research Expertise
The goal of our research is to develop non-invasive and non-destructive techniques for the study of Alzheimer’s Disease and arthritis. We facilitate timely clinical diagnoses by inventing and improving MRI pulse sequences and hardware. Our multi-nuclear and relaxometric techniques are routinely applied in model systems as well as in clinical research. We maintain active partnerships with faculty from Pathology, Neurology, Orthopedic Surgery and Rheumatology departments and recruit doctoral candidates from Biophysics and Bioengineering graduate programs.Selected Publications
Berger Rachelle, Fry Bryan, Fenty Matthew; Maurer Philip M,Elliott Dawn M.,Borthakur Arijitt: Predictability of Painful Discs using T1ρ MRI and Disc Height in Patients with Lower Back Pain. The Spine Journal (in press) 2012.Haris Mohammad, Singh Anup, Cai Kejia, McArdle Erin, Fenty Matthew, Davatzikos Christos, Trojanowski John Q, Melhem Elias R, Clark Christopher M, Borthakur Arijitt: T(1rho) MRI in Alzheimer's Disease: Detection of Pathological Changes in Medial Temporal Lobe. Journal of Neuroimaging 21(2): 86-90, Apr 2011.
Mosher Timothy J, Zhang Zheng, Reddy Ravinder, Boudhar Sanaa, Milestone Barton N, Morrison William B, Kwoh C Kent, Eckstein Felix, Witschey Walter R T, Borthakur Arijitt: Knee articular cartilage damage in osteoarthritis: analysis of MR image biomarker reproducibility in ACRIN-PA 4001 multicenter trial. Radiology 258(3): 832-42, Mar 2011.
Borthakur Arijitt, Maurer Philip M, Fenty Matthew, Wang Chenyang, Berger Rachelle, Yoder Jonathon, Balderston Richard A, Elliott Dawn M: T1ρ MRI and Discography Pressure as Novel Biomarkers for Disc Degeneration and Low Back Pain. Spine Page: epub ahead of print, Feb 2011.
Wang Chenyang, Witschey Walter, Elliott Mark A, Borthakur Arijitt, Reddy Ravinder: Measurement of intervertebral disc pressure with T(1rho) MRI. Magnetic resonance in medicine 64: 1721–1727, Dec 2010.
Wang Chenyang, Witschey Walter, Goldberg Ari, Elliott Mark, Borthakur Arijitt, Reddy Ravinder: Magnetization transfer ratio mapping of intervertebral disc degeneration. Magnetic resonance in medicine 64: 1520–1528, Nov 2010.
Haris Mohammad, Singh Anup, Cai Kejia, Davatzikos Christos, Trojanowski John Q, Melhem Elias R, Clark Christopher M, Borthakur Arijitt: T1rho (T(1ρ)) MR imaging in Alzheimer' disease and Parkinson's disease with and without dementia. Journal of neurology 258(3): 380-5, Oct 2010.
Witschey Walter R T, Borthakur Arijitt, Fenty Matt, Kneeland Bruce J, Lonner Jess H, McArdle Erin L, Sochor Matt, Reddy Ravinder: T1rho MRI quantification of arthroscopically confirmed cartilage degeneration. Magnetic resonance in medicine 63(5): 1376-82, May 2010.
Wang Chenyang, McArdle Erin, Fenty Matthew, Witschey Walter, Elliott Mark, Sochor Matthew, Reddy Ravinder, Borthakur Arijitt: Validation of sodium magnetic resonance imaging of intervertebral disc. Spine 35(5): 505-10, Mar 2010.
Witschey Walter R T, Borthakur Ari, Elliott Mark A, Magland Jeremy, McArdle Erin L, Wheaton Andrew, Reddy Ravinder: Spin-locked balanced steady-state free-precession (slSSFP). Magnetic resonance in medicine 62(4): 993-1001, Oct 2009.