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Lorraine E Levitt Katz, MD
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Professor of Pediatrics (Endocrinology and Diabetes) at the Children's Hospital of Philadelphia
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Assistant Physician, The Children's Hospital of Philadelphia, University of Pennsylvania
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International Patient Liaison for Endocrinology,, The Children's Hospital of Philadelphia
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Advisory Board, ITMAT, University of Pennsylvania
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Department: Pediatrics
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Contact information
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The Children's Hospital of Philadelphia
41 34th & Civic Center Blvd.
Philadelphia, PA 19104-4399
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41 34th & Civic Center Blvd.
Philadelphia, PA 19104-4399
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Office: 2155903174
30 Fax: 2155903053
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30 Fax: 2155903053
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Email:
katzl@email.chop.edu
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katzl@email.chop.edu
Links
8b Medical mystery author
8e The longest-running study of type 2 diabetes in young people, Longitudinal Outcomes in Youth with Type 2 Diabetes—The TODAY2 Study, is winding down. Results to date show that youth-onset type 2 diabetes is more aggressive than adult-onset disease.
a4 Penn News Today June 2013
17 Session Reports Latest from TODAY2 Research
ae Weight loss threshold for improving insulin sensitivity
17 Research Suggests Youth-onset Type 2 Diabetes More Severe than Adult-onset Disease
17 T2D in Teens: More Severe Complications. 65 Investigator Dr Lorraine Levitt Katz provides an update of the data presented at ADA 2019.
d6 ITMAT
6c 2025 Diabetes Trailblazers
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8b Medical mystery author
8e The longest-running study of type 2 diabetes in young people, Longitudinal Outcomes in Youth with Type 2 Diabetes—The TODAY2 Study, is winding down. Results to date show that youth-onset type 2 diabetes is more aggressive than adult-onset disease.
a4 Penn News Today June 2013
17 Session Reports Latest from TODAY2 Research
ae Weight loss threshold for improving insulin sensitivity
17 Research Suggests Youth-onset Type 2 Diabetes More Severe than Adult-onset Disease
17 T2D in Teens: More Severe Complications. 65 Investigator Dr Lorraine Levitt Katz provides an update of the data presented at ADA 2019.
d6 ITMAT
6c 2025 Diabetes Trailblazers
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Education:
21 9 B.A. 14 (Biology) c
3c Barnard College/Columbia University, 1984.
21 9 M.D. c
45 University of Connecticut School of Medicine, 1989.
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Permanent link21 9 B.A. 14 (Biology) c
3c Barnard College/Columbia University, 1984.
21 9 M.D. c
45 University of Connecticut School of Medicine, 1989.
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26 insulin resistance in children
22 type 2 diabetes in children
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29 pediatric carbohydrate metabolism
1e pediatric endocrinology
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20 patient-oriented research
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Description of Research Expertise
30 insulin-like growth factor axis26 insulin resistance in children
22 type 2 diabetes in children
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Description of Clinical Expertise
23 pediatric diabetes29 pediatric carbohydrate metabolism
1e pediatric endocrinology
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Description of Other Expertise
23 resident education20 patient-oriented research
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d7 Koren, Dorit; Knutson, Kristen L.; Burke, Brian K.; Drews, Kimberly; Bacha, Fida; Katz, Lorraine, Marcus, Marsha; McKay, Siripoom; Nadeau, Kristen; Mokhlesi, Babak 137 : The Association of Self-Reported Sleep andCircadian Measures with Glycemic Control and Diabetes Complications among Young Adults with Type 2 Diabetes: Results from the TODAY2 Study. American Journal of Physiology-Heart and Circulatory Physiology 1(326): H1386-H1395, June 2024.
1be Soo Heon Kwak 1,2, Shylaja Srinivasan 3, Ling Chen 4, Jennifer Todd 5, Josep M Mercader 2,4,6, Elizabeth T Jensen 7, Jasmin Divers 8, Amy K Mottl 9, Catherine Pihoker 10, Rachelle G Gandica 11, Lori M Laffel 12, Elvira Isganaitis 12, Morey W Haymond 13, Lynne L Levitsky 14, Toni I Pollin 15, Jose C Florez 2,4,6, Jason Flannick 2,16,17,✉; Progress in Diabetes Genetics in Youth (ProDiGY) consortium 9c : Genetic Architecture and Biology of Youth-Onset Type 2 Diabetes. Nat Metab 6(2):: 226–237, Jan 2024 Notes: doi: 10.1038/s42255-023-00970-0 14
cb Barbara Braffett, Fida Bacha; Laure El ghormli; Amy Shah; Santica Marcovina; Lorraine Levitt Katz; Steven Willi; Sonia Caprio; Ruban Dhaliwal; Samuel Gidding c4 : Candidate Biomarkers as Predictors of Future Kidney Disease and Cardiovascular Dysfunction in Adolescents with Type 2 Diabetes Corresponding. Diabetes Research and Clinical Practice 4 2b 199: 110671, May 2023.
213 Lynne L Levitsky, Kimberly L Drews, Rose A. Glubitosi-Klug, Lori Laffel, Lorraine E Levitt Katz, Mihai Mittelu, William Tamborlane, Jeanie B. Tryggestad, Ruth S. Weinstock, for the TODAY Study Group: The Obesity Paradox: Retinopathy, Obesity, and Circulating Risk Markers in Youth with Type 2 Diabetes in the TODAY Study. Journal of Diabetes and its Complications 36(11): 108259, November 2022 Notes: doi: 10.1016/j.jdiacomp.2022.108259. Epub 2022 Jul 19.
46 Sheela N. Magge, MD, MSCEa 16 , *Risa M. Wolf, MDa 26 , Laura Pyle, PhDb 4 , Elizabeth A. d Brown, MPHa 22 , Valeria C. Benavides, MD, MPHc 19 , Monica E. Bianco, MDd 1a , Lily C. Chao, MDe 5 , 14 Anna Cymbaluk, MDf 20 , Pinar Gumus Balikcioglu, MDg 30 , Kelsee Halpin, MD, MPHh 6 , Daniel S. Hsia, 5 MDi 1a , Lina Huerta-Saenz, MDj 14 , Jane J. Kim, MDk 31 , Seema Kumar, MDl 7 , Lorraine E Levitt Katz, 22 MDm, Brynn E. Marks, MD, MSHPEdn 14 , Anna Neyman, MDo 2b , Katie L. O’Sullivan, MDp 8 , Sabitha 18 Sasidharan Pillai, MDq 18 , Amy S. Shah, MD, MSr 34 , Ashley H. Shoemaker, MD, MSCIs 9 , Juwairriyyah 15 A. W. Siddiqui, MDt 1b , Shylaja Srinivasan, MDu 16 , Inas H Thomas, MDv 23 , Jeanie B. Tryggestad, MDw 10 , 15 Maha F. Yousif, MDx 45 , Megan M. Kelsey, MD, MSb 11 on behalf of the COVID-19 and Type 2 ef 12 Diabetes Consortium^: The COVID-19 pandemic is associated with a substantial rise in frequency and severity of presentation of youth-onset type 2 diabetes. Journal of Pediatrics 251(Suppl), August 2022.
105 Mary Ellen Vajravelu*, Joseph M. Kindler, Babette S. Zemel, Abbas Jawad, Dorit Koren,Preneet Brar, Lee J. Brooks, Jessica Reiner and Lorraine E. Levitt Katz: Visceral adiposity is related to insulin sensitivity 32 and inflammation in adolescents with obesity and 98 mild sleep disordered breathing. Journal of Pediatric Endocrinology and Metabolism 35(8): 1069–1077, Aug 2022 Notes: doi.org/10.1515/jpem-2021 36 published online July 11, 2022.
1da Higgins J, Zeitler P, Drews KL, Arslanian S, Copeland K, Goland R, Klingensmith G, Lipman TH, Tollefsen S; TODAY Study Group: ZnT8 autoantibody prevalence is low in youth with type 2 diabetes and associated with higher insulin sensitivity, lower insulin secretion, and lower disposition index. J Clin Transl Endocrinol 29: 100300. Journal of Clinical & Translational Endocrinology Volume 29, May 2022.
2c 11d Shah RD, Braffett BH, Tryggestad JB, Hughan KS, Dhaliwal R, Nadeau KJ, Levitt Katz LE, Gidding SS. for The TODAY Study Group: Cardiovascular risk factor progression in adolescents and young adults with youth-onset type 2 diabetes. Journal of Diabetes and its Complications 29 . 36(3), March 2022.
1c8 TODAY Study Group: Marsha D. Marcus, Rachelle Gandica, Laure El Ghormli, Janine Higgins, Bereket Tesfaldet, Dorit Koren, Sarah Macleish, Elia Nila Escaname, Ruth S. Weinstock: Longitudinal Association of Depressive Symptoms, Binge Eating, and Quality of Life With Cardiovascular Risk Factors in Young Adults With Youth-Onset Type 2 Diabetes: Diabetes Care 45 (1073-81), March 2022.
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Selected Publications
20c Lorraine E. Levitt Katz, MD1, Samuel S. Gidding, MD2, James D. Otvos, PhD3, Kimberly Drews, PhD4, Fida Bacha, MD5, Steven Willi, MD1, Santica Marcovina, PhD ScD6, Siripoom McKay, MD5, and Ruth S. Weinstock MD PhD7, for the TODAY Study Group* : Atherogenic Lipoproteins Associate with Loss of Glycemic Control in Youth-Onset Type 2 Diabetes: Results from the TODAY Study Journal of Clinical Lipidology. Elsevir, Supplement(S1933-2874): 1-10, Feb 2025.d7 Koren, Dorit; Knutson, Kristen L.; Burke, Brian K.; Drews, Kimberly; Bacha, Fida; Katz, Lorraine, Marcus, Marsha; McKay, Siripoom; Nadeau, Kristen; Mokhlesi, Babak 137 : The Association of Self-Reported Sleep andCircadian Measures with Glycemic Control and Diabetes Complications among Young Adults with Type 2 Diabetes: Results from the TODAY2 Study. American Journal of Physiology-Heart and Circulatory Physiology 1(326): H1386-H1395, June 2024.
1be Soo Heon Kwak 1,2, Shylaja Srinivasan 3, Ling Chen 4, Jennifer Todd 5, Josep M Mercader 2,4,6, Elizabeth T Jensen 7, Jasmin Divers 8, Amy K Mottl 9, Catherine Pihoker 10, Rachelle G Gandica 11, Lori M Laffel 12, Elvira Isganaitis 12, Morey W Haymond 13, Lynne L Levitsky 14, Toni I Pollin 15, Jose C Florez 2,4,6, Jason Flannick 2,16,17,✉; Progress in Diabetes Genetics in Youth (ProDiGY) consortium 9c : Genetic Architecture and Biology of Youth-Onset Type 2 Diabetes. Nat Metab 6(2):: 226–237, Jan 2024 Notes: doi: 10.1038/s42255-023-00970-0 14
cb Barbara Braffett, Fida Bacha; Laure El ghormli; Amy Shah; Santica Marcovina; Lorraine Levitt Katz; Steven Willi; Sonia Caprio; Ruban Dhaliwal; Samuel Gidding c4 : Candidate Biomarkers as Predictors of Future Kidney Disease and Cardiovascular Dysfunction in Adolescents with Type 2 Diabetes Corresponding. Diabetes Research and Clinical Practice 4 2b 199: 110671, May 2023.
213 Lynne L Levitsky, Kimberly L Drews, Rose A. Glubitosi-Klug, Lori Laffel, Lorraine E Levitt Katz, Mihai Mittelu, William Tamborlane, Jeanie B. Tryggestad, Ruth S. Weinstock, for the TODAY Study Group: The Obesity Paradox: Retinopathy, Obesity, and Circulating Risk Markers in Youth with Type 2 Diabetes in the TODAY Study. Journal of Diabetes and its Complications 36(11): 108259, November 2022 Notes: doi: 10.1016/j.jdiacomp.2022.108259. Epub 2022 Jul 19.
46 Sheela N. Magge, MD, MSCEa 16 , *Risa M. Wolf, MDa 26 , Laura Pyle, PhDb 4 , Elizabeth A. d Brown, MPHa 22 , Valeria C. Benavides, MD, MPHc 19 , Monica E. Bianco, MDd 1a , Lily C. Chao, MDe 5 , 14 Anna Cymbaluk, MDf 20 , Pinar Gumus Balikcioglu, MDg 30 , Kelsee Halpin, MD, MPHh 6 , Daniel S. Hsia, 5 MDi 1a , Lina Huerta-Saenz, MDj 14 , Jane J. Kim, MDk 31 , Seema Kumar, MDl 7 , Lorraine E Levitt Katz, 22 MDm, Brynn E. Marks, MD, MSHPEdn 14 , Anna Neyman, MDo 2b , Katie L. O’Sullivan, MDp 8 , Sabitha 18 Sasidharan Pillai, MDq 18 , Amy S. Shah, MD, MSr 34 , Ashley H. Shoemaker, MD, MSCIs 9 , Juwairriyyah 15 A. W. Siddiqui, MDt 1b , Shylaja Srinivasan, MDu 16 , Inas H Thomas, MDv 23 , Jeanie B. Tryggestad, MDw 10 , 15 Maha F. Yousif, MDx 45 , Megan M. Kelsey, MD, MSb 11 on behalf of the COVID-19 and Type 2 ef 12 Diabetes Consortium^: The COVID-19 pandemic is associated with a substantial rise in frequency and severity of presentation of youth-onset type 2 diabetes. Journal of Pediatrics 251(Suppl), August 2022.
105 Mary Ellen Vajravelu*, Joseph M. Kindler, Babette S. Zemel, Abbas Jawad, Dorit Koren,Preneet Brar, Lee J. Brooks, Jessica Reiner and Lorraine E. Levitt Katz: Visceral adiposity is related to insulin sensitivity 32 and inflammation in adolescents with obesity and 98 mild sleep disordered breathing. Journal of Pediatric Endocrinology and Metabolism 35(8): 1069–1077, Aug 2022 Notes: doi.org/10.1515/jpem-2021 36 published online July 11, 2022.
1da Higgins J, Zeitler P, Drews KL, Arslanian S, Copeland K, Goland R, Klingensmith G, Lipman TH, Tollefsen S; TODAY Study Group: ZnT8 autoantibody prevalence is low in youth with type 2 diabetes and associated with higher insulin sensitivity, lower insulin secretion, and lower disposition index. J Clin Transl Endocrinol 29: 100300. Journal of Clinical & Translational Endocrinology Volume 29, May 2022.
2c 11d Shah RD, Braffett BH, Tryggestad JB, Hughan KS, Dhaliwal R, Nadeau KJ, Levitt Katz LE, Gidding SS. for The TODAY Study Group: Cardiovascular risk factor progression in adolescents and young adults with youth-onset type 2 diabetes. Journal of Diabetes and its Complications 29 . 36(3), March 2022.
1c8 TODAY Study Group: Marsha D. Marcus, Rachelle Gandica, Laure El Ghormli, Janine Higgins, Bereket Tesfaldet, Dorit Koren, Sarah Macleish, Elia Nila Escaname, Ruth S. Weinstock: Longitudinal Association of Depressive Symptoms, Binge Eating, and Quality of Life With Cardiovascular Risk Factors in Young Adults With Youth-Onset Type 2 Diabetes: Diabetes Care 45 (1073-81), March 2022.
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