Kathleen O'Neil Degnan, MD
Assistant Professor of Clinical Medicine (Infectious Diseases)
Attending Physician, Hospital of the University of Pennsylvania
Attending Physician, Penn Presbyterian Medical Center
Director of Antimicrobial Stewardship, HUP Cedar Campus
Director of Antimicrobial Stewardship, Hospital of the University of Pennsylvania
Department: Medicine
Contact information
Hospital of the University of Pennsylvania, 3 Silverstein Pavilion
Philadelphia, PA 19104
Philadelphia, PA 19104
Education:
BA (Business Administration)
University of Notre Dame, 2006.
PostBac (Pre-medical)
Bryn Mawr College, 2007.
MD
University of Pennsylvania Perelman School of Medicine, 2012.
Permanent linkBA (Business Administration)
University of Notre Dame, 2006.
PostBac (Pre-medical)
Bryn Mawr College, 2007.
MD
University of Pennsylvania Perelman School of Medicine, 2012.
Description of Clinical Expertise
Antimicrobial StewardshipTransplant Infectious Diseases
General Infectious Diseases
COVID-19
Description of Research Expertise
Antimicrobial StewardshipUndergraduate Medical Education
Selected Publications
Hamilton KW, Hua E, Dutcher L, Fernandez Lynch H, Junker P, Doucette AG, Werner D, Kannel EZ, Civitello T, Gabriel P, Ahya VN, Jacobs DA, Garfall A, Pratz K, Degnan KO, Blumberg EA, Capozzi D, Craig E, Takach P, Payne AS, Geara A, Koenig H, Holzman L, Tebas P.: Implementation of an Approach to Equitable Allocation of SARS-CoV-2 Monoclonal Antibodies for Preexposure Prophylaxis: Experience From a Single Medical Center. Open Forum Infectious Diseases 11(8): ofae388, July 2024.Harrigan JJ, Hamilton KW, Cressman L, Bilker WB, Degnan KO, David MZ, Tran D, Pegues DA, Dutcher L.: Antibiotic Prescribing Patterns for Respiratory Tract Illnesses Following the Conclusion of an Education and Feedback Intervention in Primary Care. Clinical Infectious Diseases 78(5): 1120-1127, May 2024.
Serletti L, Dutcher L, Degnan KO, Szymczak JE, Cluzet V, David, MZ, Cressman L, Glassman LW, Hamilton, KW : Analysis of seasonal variation of antibiotic prescribing for respiratory tract diagnoses in primary care practices. Antimicrobial Stewardship & Healthcare Epidemiology 3(1): e147, September 2023.
Anesi GL, Degnan K, Dutcher L, Saw S, Maguire C, Binkley A, Patel S, Athans V, Barton TD, Binkley S, Candeloro CL, Herman DJ, Kasbekar N, Kennedy L, Millstein JH, Meyer NJ, Talati NJ, Patel H, Pegues DA, Sayre PJ, Tebas P, Terico AT, Murphy KM, O'Donnell JA, White M, Hamilton KW.: The Penn Medicine COVID-19 Therapeutics Committee-Reflections on a Model for Rapid Evidence Review and Dynamic Practice Recommendations During a Public Health Emergency. Open Forum Infect Dis. 10(8): ofab231, August 2023.
Sara Rendell, Eric Goren, Keith W. Hamilton, Kathleen O. Degnan. : Accessible Antibiotic Stewardship: Development of an Open-source, Interactive Online Curriculum ID Week October 2022 Notes: Poster Presentation.
Kathleen O. Degnan; Stephen Saw; Tiffany Lee; Vasilios Athans; Sonal Patel; Shawn Binkley; Joy Uzoma; Keith W. Hamilton; David Do; Lauren Dutcher. : Impact of a Real-Time Electronic Alert on Antibiotic Treatment Duration for Pneumonia in Hospitalized Patients ID Week October 2022 Notes: Poster Presentation.
Dutcher L, Degnan K, Adu-Gyamfi AB, Lautenbach E, Cressman L, David MZ, Cluzet V, Szymczak JE, Pegues DA, Bilker W, Tolomeo P, Hamilton KW. : Improving Outpatient Antibiotic Prescribing for Respiratory Tract Infections in Primary Care: A Stepped-Wedge Cluster Randomized Trial. Clinical infectious diseases IDSA 74(6): 56-63, March 2022.
Degnan KO, Cluzet V, David MZ, Dutcher L, Cressman L, Lautenbach E, Hamilton KW: Development and validation of antibiotic stewardship metrics for outpatient respiratory tract diagnoses and association of provider characteristics with inappropriate prescribing. Infection Control and Hospital Epidemiology 43(1): 56-63, Jan 2022.
Wein M, Binkley S, Athans V, Saw S, Lee T, Patel S, Hamilton KW, Binkley A, Degnan K, Glaser L, Dutcher L, Talati NJ, Richard-Greenblatt M.: Assessment of Clinical Outcomes and Antibiotic Prescribing Patterns Following Implementation of the GenMark ePlex® Blood Culture Identification Panel for Gram-positive Bloodstream Infections. Open Forum Infect Dis. 4(8), December 2021.
Bar KJ, Shaw PA, Choi GH, Aqui N, Fesnak A, Yang JB, Soto-Calderon H, Grajales L, Starr J, Andronov M, Mastellone M, Amonu C, Feret G, DeMarshall M, Buchanan M, Caturla M, Gordon J, Wanicur A, Monroy MA, Mampe F, Lindemuth E, Gouma S, Mullin AM, Barilla H, Pronina A, Irwin L, Thomas R, Eichinger RA, Demuth F, Luning Prak ET, Pascual JL, Short WR, Elovitz MA, Baron J, Meyer NJ, Degnan KO, Frank I, Hensley SE, Siegel DL, Tebas P.: A randomized controlled study of convalescent plasma for individuals hospitalized with COVID-19 pneumonia. The Journal of Clinical Investigation 131(24): e155114, December 2021.