Amish C. Shah, MD, PhD

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Assistant Professor of Clinical Pediatrics (Oncology)
Attending Physician, Neuro-Oncology Section, Division of Oncology, Children's Hospital of Philadelphia
Director, Pediatric Neuro-Oncology Fellowship Program, Children's Hospital of Philadelphia
Director, Retinoblastoma Program, Division of Oncology, Children's Hospital of Philadelphia
Department: Pediatrics

Contact information
Children’s Hospital of Philadelphia
CHOP Hub for Clinical Collaboration, Suite 3587
Center for Childhood Cancer Research and Division of Oncology
3400 S 34th St
Philadelphia, PA 19104
Philadelphia, PA 19104
Office: 267-426-7598
Fax: 215-590-9956
Education:
BS (Biochemistry & Molecular Biology)
University of Georgia, 1999.
PhD (Medical Scientist Training Program )
University of Alabama School of Medicine, 2006.
MD
University of Alabama School of Medicine, 2008.
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Description of Clinical Expertise

Pediatric Neuro-oncology
Retinoblastoma
Neurofibromatosis Type 1
Neurofibromatosis Type 2
CNS Histiocytic Diseases

Description of Research Expertise

Retinoblastoma clinical trials
Neurofibromatosis clinical trials

Selected Publications

Emily Xu, Phillip Storm, Alexander Tucker, Peter Madsen, Iris Paltin, Jimmy Huh, J. Michael King, Emily Zhang, Kristen Park, Mahaa Ayub, Shih-Shan Chen: Medical management of cerebellar mutism syndrome at a quaternary Children’s Hospital. Child’s Nervous System Feb 2025 Notes: doi: 10.1007/s00381-025-06759-8.

Debra L. Friedman, Emma Schremp, Tatsuki Koyama, Lili Sun, Lori Ann Kehler, Anthony Daniels, Robert J. Hayashi, Amish C. Shah, Helen Dimaras, Rajaram Nagarajan, Mary Lou Schmidt, Murali M. Chintagumpala, Cynthia E. Herzog, Sandra Luna-Fineman, Claire Elyse Fraley, Joanna Weinstein, Thomas Arthur Olson, Bruce Crooks, Cindy L. Schwartz, and Joseph Philip Neglia. : Outcomes in contemporary patients with retinoblastoma: The RIVERBOAT Consortium. ASCO 2025.

Mentors: M. Fisher, D. Licht (Neurology) Co-authors: S. Wang, Y. Li : Arterial Spin Labeling MRI in the diagnosis and prediction of progression of pediatric brain tumors. Data analysis completed, manuscript being written 2025.

Co-authors: S. Pultman, T. Jubelirer: Use and perceptions of cannabis and cannabinoids amongst pediatric oncology families. Data collection ongoing 2025.

Leahey AM, Shah AC, Shields CL. : Three vs 6 Cycles of Adjuvant Chemotherapy for Retinoblastoma. JAMA Ophthalmol Page: 1;142(12):1107-1108. Dec 2024.

Pascual-Pasto G, et. al. : Targeting GPC2 on Intraocular and CNS Metastatic Retinoblastomas with Local and Systemic Delivery of CAR T Cells. Clin Cancer Res Page: 15;30(16):3578-3591, Aug 2024.

Newman H, et. al. : B-cell acute lymphoblastic leukemia and juvenile xanthogranuloma in a patient with ETV6 thrombocytopenia and leukemia predisposition syndrome: novel clinical presentation and perspective. Haematologica Page: 1;109(5):1624-1627, May 2024.

Ercan AB, et. al. : The Clinical and Biological Landscape of Constitutional Mismatch Repair Deficiency: An IRRDC Cohort Study. The Lancet Oncology 25(5): 668-682, May 2024.

Parekh D, et al. : Clofarabine monotherapy in aggressive, relapsed and refractory Langerhans cell histiocytosis. Haematol. Page: 204(5):1888-1893, May 2024.

Kotch C, Dombi E, Shah AC, Smith K, Brown S, Li Y, Widemann BC, Fisher MJ.: Retrospective Cohort Analysis of the Impact of Puberty on Plexiform Neurofibroma Growth in Patients with Neurofibromatosis Type 1. J Pediatr. 260(1): 113513, Sep 2023.

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Last updated: 02/24/2025
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