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Lucie Guo
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Assistant Professor of Ophthalmology
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Department: Ophthalmology
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Contact information
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51 North 39th Street
Philadelphia, PA
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Philadelphia, PA
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Education:
21 7 BA 21 (Biochemical Sciences) c
2b Harvard University, 2010.
21 7 MD 15 (Medicine) c
33 University of Pennsylvania, 2014.
21 8 PhD 37 (Biochemistry and Biophysics: Ben Black Lab) c
33 University of Pennsylvania, 2018.
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Permanent link21 7 BA 21 (Biochemical Sciences) c
2b Harvard University, 2010.
21 7 MD 15 (Medicine) c
33 University of Pennsylvania, 2014.
21 8 PhD 37 (Biochemistry and Biophysics: Ben Black Lab) c
33 University of Pennsylvania, 2018.
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10c Soetikno BT, Ghoraba H, Brant A, DeBoer C, Guo L, Shue A, Hartnett ME.: Retinal racemose hemangioma presenting with a chorioretinal anastomosis. Am J Ophthalmol Case Rep 36(16): 102188, Oct 2024.
d1 Guo LY, Mishra K, Leung LB.: Severe progression of pentosan maculopathy over a decade. Am J Ophthalmol Case Rep 30(8): 101826, Mar 2023.
e9 Kempton HR, Love KS, Guo LY, Qi LS.: Scalable biological signal recording in mammalian cells using Cas12a base editors. Nat Chem Biol 18(7): 742-750, July 2022.
13d Guo LY, Bian J, Davis AE, Liu P, Kempton HR, Zhang X, Chemparathy A, Gu B, Lin X, Rane DA, Xu X, Jamiolkowski RM, Hu Y, Wang S, Qi LS.: Multiplexed genome regulation in vivo with hyper-efficient Cas12a. Nat Cell Biol 24(4): 590-600, April 2022.
ef Guo LY, Jamiolkowski RM, Hassan M, Leng T.: A buoyant mass in the brain: Intraventricular migration of silicone oil. Am J Ophthalmol Case Rep 25(3): 101399, Feb 2022.
11c Zasadzińska E, Huang J, Bailey AO, Guo LY, Lee NS, Srivastava S, Wong KA, French BT, Black BE, Foltz DR.: Inheritance of CENP-A Nucleosomes during DNA Replication Requires HJURP. Dev Cell 47: 348-362, Nov 2018.
13b Stankovic A, Guo LY, Mata JF, Bodor DL, Cao XJ, Bailey AO, Shabanowitz J, Hunt DF, Garcia BA, Black BE, Jansen LET.: A Dual Inhibitory Mechanism Sufficient to Maintain Cell-Cycle-Restricted CENP-A Assembly. Mol Cell 65(19): 231-246, Jan 2017.
142 Falk SJ, Guo LY, Sekulic N, Smoak EM, Mani T, Logsdon GA, Gupta K, Jansen LE, Van Duyne GD, Vinogradov SA, Lampson MA, Black BE.: Chromosomes. CENP-C reshapes and stabilizes CENP-A nucleosomes at the centromere. Science 348(6235): 699-703, May 2015.
da Jamiolkowski RM, Guo LY, Li YR, Shaffer SM, Naji A.: Islet transplantation in type I diabetes mellitus. Yale J Biol Med 85(1): 37-43, March 2012.
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Selected Publications
ad Thakur S, Guo LY, Mruthyunjaya P.: An Unusual Pigmented Lesion. Ophthalmology 132(1): e14, Jan 2025.10c Soetikno BT, Ghoraba H, Brant A, DeBoer C, Guo L, Shue A, Hartnett ME.: Retinal racemose hemangioma presenting with a chorioretinal anastomosis. Am J Ophthalmol Case Rep 36(16): 102188, Oct 2024.
d1 Guo LY, Mishra K, Leung LB.: Severe progression of pentosan maculopathy over a decade. Am J Ophthalmol Case Rep 30(8): 101826, Mar 2023.
e9 Kempton HR, Love KS, Guo LY, Qi LS.: Scalable biological signal recording in mammalian cells using Cas12a base editors. Nat Chem Biol 18(7): 742-750, July 2022.
13d Guo LY, Bian J, Davis AE, Liu P, Kempton HR, Zhang X, Chemparathy A, Gu B, Lin X, Rane DA, Xu X, Jamiolkowski RM, Hu Y, Wang S, Qi LS.: Multiplexed genome regulation in vivo with hyper-efficient Cas12a. Nat Cell Biol 24(4): 590-600, April 2022.
ef Guo LY, Jamiolkowski RM, Hassan M, Leng T.: A buoyant mass in the brain: Intraventricular migration of silicone oil. Am J Ophthalmol Case Rep 25(3): 101399, Feb 2022.
11c Zasadzińska E, Huang J, Bailey AO, Guo LY, Lee NS, Srivastava S, Wong KA, French BT, Black BE, Foltz DR.: Inheritance of CENP-A Nucleosomes during DNA Replication Requires HJURP. Dev Cell 47: 348-362, Nov 2018.
13b Stankovic A, Guo LY, Mata JF, Bodor DL, Cao XJ, Bailey AO, Shabanowitz J, Hunt DF, Garcia BA, Black BE, Jansen LET.: A Dual Inhibitory Mechanism Sufficient to Maintain Cell-Cycle-Restricted CENP-A Assembly. Mol Cell 65(19): 231-246, Jan 2017.
142 Falk SJ, Guo LY, Sekulic N, Smoak EM, Mani T, Logsdon GA, Gupta K, Jansen LE, Van Duyne GD, Vinogradov SA, Lampson MA, Black BE.: Chromosomes. CENP-C reshapes and stabilizes CENP-A nucleosomes at the centromere. Science 348(6235): 699-703, May 2015.
da Jamiolkowski RM, Guo LY, Li YR, Shaffer SM, Naji A.: Islet transplantation in type I diabetes mellitus. Yale J Biol Med 85(1): 37-43, March 2012.
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