Allison Barz Leahy, MD MSCE
Assistant Professor of Pediatrics (Oncology) at the Children's Hospital of Philadelphia
Attending Physician, Division of Oncology, Children's Hospital of Philadelphia
Core Faculty, Clinical Futures, Children's Hospital of Philadelphia
Faculty Member, Center for Cancer Care Innovation, University of Pennsylvania
Abramson Cancer Center (ACC) Cancer Research Training and Education (CRTEC) Representative, Penn Medicine
Clinical Director, CART Data Infrastructure, Cellular Therapy and Transplant Section, Children's Hospital of Philadelphia
Department: Pediatrics
Contact information
Children's Hospital of Philadelphia
HUB For Clinical Collaboration
3500 Civic Center Boulevard
Philadelphia, PA 19104
HUB For Clinical Collaboration
3500 Civic Center Boulevard
Philadelphia, PA 19104
Office: 267-253-8133
Email:
barza@chop.edu
barza@chop.edu
Education:
BA (Russian Language Major, Chemistry Minor)
Bowdoin College , 2005.
MA (Biological Sciences)
Hunter College of the City of New York, 2008.
MD
SUNY Upstate Medical University, 2012.
MSCE
University of Pennsylvania, 2020.
Permanent linkBA (Russian Language Major, Chemistry Minor)
Bowdoin College , 2005.
MA (Biological Sciences)
Hunter College of the City of New York, 2008.
MD
SUNY Upstate Medical University, 2012.
MSCE
University of Pennsylvania, 2020.
Description of Clinical Expertise
Patient-reported outcomes (PROs), relapsed and refractory leukemia, CAR T cellsDescription of Research Expertise
Patient-reported outcomes (PROs), pediatric health outcomes, phase 1 clinical trials, relapsed and refractory leukemia, pediatric oncologySelected Publications
Thorton C, Daniali M, Wang L, Makeneni S, Leahy AB : Using natural language processing to identify symptomatic adverse events in pediatric oncology: Tutorial for clinician researchers. JMIR Page: Accepted, Oct 2025.Thornton, CP, Wang, L, Makeneni, S, Leahy, A: Reliability of artificial intelligence in identifying symptomatic adverse events during therapy: Results of a pilot study. Podium Presentation, International Society of Paediatric Oncology, Amsterdam, The Netherlands Oct 2025.
Diorio C, Myers RM, Li Y, Liu H, Belfer S, DiNofia A, Leahy AB, Newman H, Dolan J, Martinez Z, Elhachimi A, Lindell RB, Mullen C, Li A, Kim J, Teachey DT, Maude SL, Grupp SA, McGuire JL: Preinfusion Risk Factors for the Development of Severe Neurotoxicity following CART Therapy in Pediatric Patients. HemaSphere Page: In Press, Sep 2025.
Zheng DJ, Wang L, Getz K, Aplenc R, Coughlin KQ, DiNofia AM, Maude SL, Myers RM, Newman H, Orsini T, Paris D, Grupp SA, Leahy AB: Financial toxicity and association with treatment outcomes during pediatric CAR T therapy. Poster Presentation, The American Society of Clinical Oncology Meeting, Chicago, IL May 2025.
Domizi P, Sarno J, Jager A, Merchant M, Pacheco KZB, Yamada-Hunter SA, Rotiroti MC, Liu Y, Baskar R, Reynolds WD, Sworder BJ, Sahaf B, Bendall SC, Mullighan CG, Alizadeh AA, Leahy AB, Myers RM, Yates B, Wang HW, Shah NN, Majzner RG, Mackall CL, Grupp SA, Barrett DM, Sotillo E, Davis KL.: IKAROS levels are associated with antigen escape in CD19- and CD22-targeted therapies for B-cell malignancies. Nat Commun 16(1): 3800, Apr 2025.
Steineck A, Chao K, Hall AG, Jacoby E, Leahy AB, Ligon JA, Luciani K, Schultz LM, Summer CN, Ward L, Winestone LE, Shah NN: Access to CARe: A Narrative of Real-World Medical Decision-Making to Access Chimeric Antigen Receptor (CAR) T-Cell Therapy in Children, Adolescents, and Young Adults. Pediatric Blood and Cancer 72(4): e31516, Apr 2025.
Friedes BD, DiNofia AM, Iannone E, Li Y, Rheingold SR, Barz Leahy A, Wray L, Callahan C, Baniewicz D, Vernau L, Getz KD, Aplenc R, Maude SL, Grupp SA, Myers RM.: Therapies and outcomes following extramedullary relapse of pediatric and young adult ALL after CD19 CAR T-cell therapy. Blood Adv 9(2): 354-359, Jan 2025.
Leahy AB, Ceppi F, Hunger SP, Conter V: Stratification and treatment considerations in B-cell precursor and T-cell acute lymphoblastic leukemia. Acute Lymphoblastic Leukemia in Children and Adolescents. Springer Nature, Page: 109-124, Dec 2024.
Basch E, Leahy AB, Reeve BB: Symptom Monitoring With Patient-Reported Outcomes During Pediatric Cancer Care JAMA 332(23): 1979-1980, Nov 2024.
Barz-Leahy A, Wang L, Paris D, Coughlin K, Orsini T, Myers R, Dinofia A, Maude SL, Grupp SA, Bekelman J, Feudtner C : PROs in pediatric immunotherapy: Longitudinal self- and proxy-reported symptoms in children treated with CAR T cells for advanced leukemia. Podium Presentation, International Society of Quality of Life (ISOQOL), Cologne, Germany Oct 2024.