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Matthew Astolfi
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Assistant Professor of Clinical Orthopaedic Surgery
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Department: Orthopaedic Surgery
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Contact information
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Penn Medicine University City
40 3737 Market Street, 6th Floor
Philadelphia, PA 19104
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40 3737 Market Street, 6th Floor
Philadelphia, PA 19104
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Office: 607-346-4496
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Email:
mastolfi@sas.upenn.edu
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mastolfi@sas.upenn.edu
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Education:
21 9 B.S. 19 (Kinesiology ) c
4b College at Brockport, State University of New York, 2011.
21 9 M.S. 3c (Exercise Science: Sports Medicine Concentration) c
2f University of Delaware, 2013.
21 9 M.D. 15 (Medicine) c
55 Sidney Kimmel Medical College of Thomas Jefferson University, 2019.
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Permanent link21 9 B.S. 19 (Kinesiology ) c
4b College at Brockport, State University of New York, 2011.
21 9 M.S. 3c (Exercise Science: Sports Medicine Concentration) c
2f University of Delaware, 2013.
21 9 M.D. 15 (Medicine) c
55 Sidney Kimmel Medical College of Thomas Jefferson University, 2019.
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71 Provide comprehensive evaluation and management of a wide range of upper extremity conditions, including:
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5d - Rotator cuff tears: partial and full-thickness tears, massive and irreparable tears
54 - Shoulder instability: recurrent dislocations, labral tears (Bankart, SLAP)
74 - Shoulder arthritis: glenohumeral osteoarthritis, inflammatory arthritis, and rotator cuff tear arthropathy
56 - Proximal humerus fractures: acute fractures and fracture malunions/nonunions
66 - Clavicle and acromioclavicular (AC) joint injuries: separations, dislocations, and fractures
2f - Frozen shoulder (adhesive capsulitis)
36 - Calcific tendinitis and impingement syndrome
43 - Elbow arthritis: osteoarthritis, post-traumatic arthritis
60 - Elbow instability: ligament injuries, terrible triad injuries, and chronic instability
6a - Elbow fractures and dislocations: including distal humerus, olecranon, and radial head fractures
4c - Lateral and medial epicondylitis (tennis elbow and golfer's elbow)
2c - Biceps and triceps tendon injuries
6a - Nerve compression syndromes: cubital tunnel syndrome and other upper extremity nerve entrapments
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1a Surgical Expertise
85 - Shoulder arthroscopy: rotator cuff repair, labral repair, biceps tenodesis, capsular release, and subacromial decompression
a7 - Shoulder replacement surgery: anatomic total shoulder arthroplasty (conventional and cuff sparing), reverse total shoulder arthroplasty, and hemiarthroplasty
4d - Revision shoulder arthroplasty, including patient specific implants
69 - Fracture fixation: open reduction and internal fixation of complex shoulder and elbow fractures
67 - Elbow arthroscopy: debridement, loose body removal, capsular release, and osteophyte excision
3d - Elbow replacement surgery, total elbow arthroplasty
6c - Ligament reconstruction ulnar collateral ligament (UCL) reconstruction and lateral ligament repair
4d - Tendon repair and reconstruction, rotator cuff, biceps, and triceps
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19 Clinical Approach
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1a0 Every patient receives an individualized treatment plan developed through shared decision-making. Nonoperative management including physical therapy, activity modification, injections, and anti-inflammatory strategies is always considered as a first-line approach when appropriate. When surgery is indicated, we utilize the latest evidence-based techniques and technologies to optimize outcomes and recovery.
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1e Specialized Population
49 - Overhead and throwing athletes with shoulder and elbow injuries
4e - Active adults with degenerative conditions of the shoulder and elbow
65 - Patients requiring complex revision surgery or reconstruction after prior failed procedures
68 - Patients with fracture complications including malunion, nonunion, and post-traumatic deformity
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Description of Clinical Expertise
23 Conditions Treated8
71 Provide comprehensive evaluation and management of a wide range of upper extremity conditions, including:
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5d - Rotator cuff tears: partial and full-thickness tears, massive and irreparable tears
54 - Shoulder instability: recurrent dislocations, labral tears (Bankart, SLAP)
74 - Shoulder arthritis: glenohumeral osteoarthritis, inflammatory arthritis, and rotator cuff tear arthropathy
56 - Proximal humerus fractures: acute fractures and fracture malunions/nonunions
66 - Clavicle and acromioclavicular (AC) joint injuries: separations, dislocations, and fractures
2f - Frozen shoulder (adhesive capsulitis)
36 - Calcific tendinitis and impingement syndrome
43 - Elbow arthritis: osteoarthritis, post-traumatic arthritis
60 - Elbow instability: ligament injuries, terrible triad injuries, and chronic instability
6a - Elbow fractures and dislocations: including distal humerus, olecranon, and radial head fractures
4c - Lateral and medial epicondylitis (tennis elbow and golfer's elbow)
2c - Biceps and triceps tendon injuries
6a - Nerve compression syndromes: cubital tunnel syndrome and other upper extremity nerve entrapments
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1a Surgical Expertise
85 - Shoulder arthroscopy: rotator cuff repair, labral repair, biceps tenodesis, capsular release, and subacromial decompression
a7 - Shoulder replacement surgery: anatomic total shoulder arthroplasty (conventional and cuff sparing), reverse total shoulder arthroplasty, and hemiarthroplasty
4d - Revision shoulder arthroplasty, including patient specific implants
69 - Fracture fixation: open reduction and internal fixation of complex shoulder and elbow fractures
67 - Elbow arthroscopy: debridement, loose body removal, capsular release, and osteophyte excision
3d - Elbow replacement surgery, total elbow arthroplasty
6c - Ligament reconstruction ulnar collateral ligament (UCL) reconstruction and lateral ligament repair
4d - Tendon repair and reconstruction, rotator cuff, biceps, and triceps
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19 Clinical Approach
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1a0 Every patient receives an individualized treatment plan developed through shared decision-making. Nonoperative management including physical therapy, activity modification, injections, and anti-inflammatory strategies is always considered as a first-line approach when appropriate. When surgery is indicated, we utilize the latest evidence-based techniques and technologies to optimize outcomes and recovery.
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1e Specialized Population
49 - Overhead and throwing athletes with shoulder and elbow injuries
4e - Active adults with degenerative conditions of the shoulder and elbow
65 - Patients requiring complex revision surgery or reconstruction after prior failed procedures
68 - Patients with fracture complications including malunion, nonunion, and post-traumatic deformity
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11b Monir JG, Astolfi MM, Sholder D, Kocovic N, Horneff JG 3rd, Abboud JA, Schoch BS.: Early revision rotator cuff repair: an analysis of outcomes and function. Eur J Orthop Surg Traumatol 33(2): 321-326. Feb 2023.
11f Hill BW, Singh AM, Astolfi M, Horneff JG, Schoch BS, Abboud JA.: Outcomes of rotator cuff repair with concurrent microfracture of focal glenohumeral osteoarthritis. J Shoulder Elbow Surg 30(7S): S66-S70, July 2021.
fe Morrissey PB, Murphy H, Astolfi MM, Sandhu H, Vaccaro AR.: Surgical Decision Making for Thoracolumbar Spine Injuries in Polytrauma Patients. Instr Course Lect 67: 353-368, Feb 2018.
120 Astolfi MM, Millhouse P, Murphy H, Schroeder G, Vaccaro AR: Thoracolumbar Fracture Classifications: Pros and Cons of the TLICS and AOSpine Classification Systems. Contemporary Spine Surgery 17(1): 1-8, January 2018.
107 Bishop M, Astolfi M, Padegimas E, DeLuca P, Hammoud S.: Venous Thromboembolism Within Professional American Sport Leagues. Orthop J Sports Med 5(12): doi: 10.1177/2325967117745530. Dec 2017.
10f Schroeder GD, Astolfi MM, Hollern DA, Vaccaro AR: Understanding the Business Challenges for a Spine Practice in the Changing Healthcare Environment. Contemporary Spine Surgery 17(7): 1-5, July 2016.
f2 Astolfi MM, Struminger AH, Royer TD, Kaminski TW, Swanik CB.: Adaptations of the Shoulder to Overhead Throwing in Youth Athletes. J Athl Train 50(7): 726-732, July 2015.
f1 Astolfi M, McGuire K, Kaminski TW.: The effectiveness of autologous conditioned serum in the treatment of knee osteoarthritis. J Sport Rehabil 23(4): 365-369, Nov 2014.
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Selected Publications
171 Brandon Fisher, MD ∙ Matthew Astolfi, MD ∙ Justin DesLaurier, MD ∙ Karen Childers, MS ∙ James Y.J. Lee, MD ∙ Marisa Samani, BA ∙ Madeleine DeClercq, BS ∙ J. Michael Wiater, MD: Polyethylene wear: an under-reported cause of failed shoulder arthroplasty. JSES International July 2025.11b Monir JG, Astolfi MM, Sholder D, Kocovic N, Horneff JG 3rd, Abboud JA, Schoch BS.: Early revision rotator cuff repair: an analysis of outcomes and function. Eur J Orthop Surg Traumatol 33(2): 321-326. Feb 2023.
11f Hill BW, Singh AM, Astolfi M, Horneff JG, Schoch BS, Abboud JA.: Outcomes of rotator cuff repair with concurrent microfracture of focal glenohumeral osteoarthritis. J Shoulder Elbow Surg 30(7S): S66-S70, July 2021.
fe Morrissey PB, Murphy H, Astolfi MM, Sandhu H, Vaccaro AR.: Surgical Decision Making for Thoracolumbar Spine Injuries in Polytrauma Patients. Instr Course Lect 67: 353-368, Feb 2018.
120 Astolfi MM, Millhouse P, Murphy H, Schroeder G, Vaccaro AR: Thoracolumbar Fracture Classifications: Pros and Cons of the TLICS and AOSpine Classification Systems. Contemporary Spine Surgery 17(1): 1-8, January 2018.
107 Bishop M, Astolfi M, Padegimas E, DeLuca P, Hammoud S.: Venous Thromboembolism Within Professional American Sport Leagues. Orthop J Sports Med 5(12): doi: 10.1177/2325967117745530. Dec 2017.
10f Schroeder GD, Astolfi MM, Hollern DA, Vaccaro AR: Understanding the Business Challenges for a Spine Practice in the Changing Healthcare Environment. Contemporary Spine Surgery 17(7): 1-5, July 2016.
f2 Astolfi MM, Struminger AH, Royer TD, Kaminski TW, Swanik CB.: Adaptations of the Shoulder to Overhead Throwing in Youth Athletes. J Athl Train 50(7): 726-732, July 2015.
f1 Astolfi M, McGuire K, Kaminski TW.: The effectiveness of autologous conditioned serum in the treatment of knee osteoarthritis. J Sport Rehabil 23(4): 365-369, Nov 2014.
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