Justin Hill Berger, MD, Ph.D
Instructor A of Pediatrics
Medical Staff, Children’s Hospital of Philadelphia
Instructor of Pediatrics, Children's Hospital of Philadelphia
Member, CHOP Cardiovascular Institute
Department: Pediatrics
Education:
A.B. (Biochemistry)
Bowdoin College, 2005.
Ph.D (Biochemistry)
Albert Einstein College of Medicine, 2014.
MD (Doctor of Medicine)
Albert Einstein College of Medicine, 2014.
Permanent linkA.B. (Biochemistry)
Bowdoin College, 2005.
Ph.D (Biochemistry)
Albert Einstein College of Medicine, 2014.
MD (Doctor of Medicine)
Albert Einstein College of Medicine, 2014.
Description of Clinical Expertise
Justin Berger, MD, PhD is an attending physician in the Division of Cardiology on the Pediatric Heart Failure and Transplantation service. His research and clinical interests focus on the development of pediatric heart failure and underlying metabolic and genetic causes. Dr. Berger sees infants, children and young adults for general pediatric cardiology as well as heart failure, cardiomyopathy and heart transplant.Description of Research Expertise
Justin Berger, MD, PhD is a pediatric physician-scientist in the CHOP Cardiovascular Institute with a research focus on how metabolic dysregulation drives cardiac dysfunction. He has particular interest in cardiomyocyte lipid homeostasis relevant to heart failure with emphasis on obesity-driven diastolic heart failure, a common entity in many forms of pediatric heart failure. This work combined basic science models with translational approaches, and has been supported by multiple intramural and NIH grants. Dr. Berger has also published on genetic causes of pediatric cardiomyopathy, risk factors for dyslipidemia in congenital heart disease, and appropriate lipid screening in these populations.Selected Publications
Berger JH, Matsuura TR, Bowman, C, Lai L, Patel J, Callaway R, Haldar S, Arany, Z, Kelly DP.: Abstract: Cardiac and generalized SGLT2 deficiency does not protect against development of Heart Failure with reduced ejection fraction in mice. AHA Scientific Sessions November 2023.Mavroudis CD, Grasty MA, Restaino K, O’Connor MJ, Wittlieb-Weber CA, Edelson JB, Edwards JJ, Berger JH, Lin KY, Rossano JW, Maeda K.: Abstract: A novel Heartmate 3 RVAD implant technique in a young patient. AATS MCS Symposium June 2023.
Berger JH, Matsuura TR, Bowman, C, Lai L, Patel J, Callaway R, Arany, Z, Kelly DP. : Abstract: Cardiac and generalized SGLT2 deficiency does not protect against development of HFrEF in mice. UPenn Department of Medicine Research Day June 2023.
Mavroudis CD, O’Connor MJ, Wittlieb-Weber CA, Edelson JB, Edwards JJ, Berger JH, Lin KY, Rossano JW, Maeda K.: Abstract: Hybrid stage 1 palliation with simultaneous off-pump ventricular assist device placement in neonates with high-risk single ventricle anatomy: initial experience. AATS May 2023.
Bell S, Berger JH, Boyle C, Edelson JB, Edwards JJ, Ha L, Lin KY, Maeda K, Rossano JW, Wittlieb-Weber CA, White R, O’Connor MJ. : Abstract: Characteristics and Outcomes of Children Determined Not to be Candidates for Heart Transplantation, ISHLT April 2023.
Edwards JJ, Mejia E, Boyle C, Ha L, O’Connor MJ, Joshi P, White R, Rossano J, Berger JH, Wittlieb-Weber CA, Lin KY, Maeda K, Edelson J. : Abstract: Donor Derived Cell Free DNA is Correlated with DSA and Rejection in Pediatric Heart Transplant Recipients. ddcfDNA is Correlated with DSA and Rejection in Pediatric Heart Transplant Recipients. ISHLT April 2023.
Berger JH, Matsuura T, Callaway R, Patel J, McDaid K, Griffin J, Shewale SV, Lai L, Kelly DP.: Abstract: Development of novel mouse models recapitulating Heart Failure with preserved Ejection Fraction (HFpEF) combining metabolic syndrome with gradual pressure overload. UPenn HFpEF Symposium. Young Investigator Abstract Finalist. March 2023.
Berger JH, Zhou J, Jaiswal N, Yamamoto T, Lai L, Titchenell PM, Kelly DP.: Abstract: MondoA protects against inflammation in obesity-driven heart failure. 2022 Child Health Research Centers Conference October 2022.
Berger JH, Zhou J, Jaiswal N, Yamamoto T, Lai L, Titchenell PM, Kelly DP. : Abstract: Cardiac MondoA deficiency results in high-fat diet-induced myocardial inflammation. Penn-Stanford CVI Symposium October 2022.
Berger JH, Zhou J, Jaiswal N, Yamamoto T, Lai L, Titchenell PM, Kelly DP.: Abstract: Cardiac MondoA deficiency results in high-fat diet-induced myocardial inflammation. UPenn Department of Medicine Research Day June 2022.