Denise J Xu, MD

faculty photo
Assistant Professor of Clinical Neurology
Assistant Program Director, Neurology Residency, University of Pennsylvania
Director for the Neurology Sub-I, University of Pennsylvania, Perelman School of Medicine
Penn PORTAL Clinician Leader, University of Pennsylvania
Department: Neurology

Contact information
Hospital of the University of Pennsylvania
3400 Spruce Street
Philadelphia, PA 19104
Education:
BA (Bachelor of Arts in Neurobiology, Magna Cum Laude, Citation in Mandarin Chinese)
Harvard College, Cambridge, MA, 2011.
MD (Medical Doctor, Certificate in Medical Education)
Perelman School of Medicine at the University of Pennsylvania, 2018.
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Description of Clinical Expertise

Inpatient neurology

Description of Other Expertise

Undergraduate medical education, graduate medical education, quality improvement

Selected Publications

Ellis CA, Liu PZ, Napole A, Denison L, Shaik NF, Venezia GA, Ljungberg L, Karamardian MA, Peachey C, Buckley M, Bae CJ, Stein L, Xu DJ: Promoting Sleep for Neurology Inpatients: The Value of Routine Overnight Vital Signs. Neurology Clinical Practice 15(4), August 2025.

Rock M, Shipley SC, Little JN, Berger J, Xu DJ: Clinical Reasoning: A 60-Year-Old Man with Rapidly Progressive Left Hemibody Weakness and Vision Loss. Neurology 105(2), July 2025.

Xu D, Cristancho D, Price R: Expanding the Inpatient General Neurology Consultation Service: An Initiative to Improve Care Delivery. American Academy of Neurology, San Diego, CA April 2025.

Liu P, Napole A, Denison L, Shaik N, Venezia G, Ljungberg L, Karamardian M, Peachey C, Buckley M, Bae C, Stein L, Xu D, Ellis C: Are Routine Overnight Vitals Necessary for Neurology Inpatients? American Academy of Neurology, San Diego, CA April 2025.

Little J, Shipley S, Rock M, Berger JR, Xu DJ: Paraneoplastic Tumefactive Demyelination with Anti-LUZP4 Antibody Associated with Metastatic Seminoma: A Case Report. American Academy of Neurology, San Diego, CA April 2025.

Eisinger RS, Jones FJ, Pai EL, Xu D, Berger JR, Prasad S: Ideomotor Apraxia and 'Milky Way' Sign in Progressive Multifocal Leukoencephalopathy. Neurology 103(10), November 2024.

Karamardian M, Stein L, Resnick D, Chambers C, Peachey C, Malinovitch A, Rosin R, Bae C, Buckley M, Xu DJ: Restoring Sleep for Neurology Inpatients. American Academy of Neurology, Denver, CO April 2024 Notes: Platform presentation and accepted abstract.

Lebron-Cruz A, Liu P, Venezia G, Ljungberg L, Peachey C, Buckley M, Karamardian M, Xu DJ, Bae C, Stein L, Ellis C: Characterizing Inpatient Sleep on the Neurology Service. American Academy of Neurology, Denver, CO April 2024 Notes: Poster and accepted abstract.

Douglas AG, Xu DJ, Shah MP: Approach to Myelopathy and Myelitis. Neurologic Clinics 40(1): 133-156, February 2022.

Xu DJ, Murphy K, Balu R, Rosenberg J: Clinical Reasoning: A Man with Rapidly Progressive Weakness and Respiratory Failure. Neurology 91(7): e686-e691, August 2018.

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Last updated: 08/01/2025
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