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Sabrina A. Gmuca, MD MSCE

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Assistant Professor of Pediatrics (Rheumatology) at the Children's Hospital of Philadelphia
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Attending Physician, Division of Rheumatology, Children's Hospital of Philadelphia
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Senior Scholar, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine
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Department: Pediatrics
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Children's Hospital of Philadelphia
3d Center for Childhood Arthritis and Rheumatic Diseases
3c 2716 South Street, 11-121
Philadelphia, PA 19104
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2e Office: 215-590-3260
32 Fax: 215-590-4750
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18 Publications
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Links
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 a1 Center for Pediatric Clinical Effectiveness
8b Policy Lab at Children's Hospital of Philadelphia
ba Center for Amplified Musculoskeletal Pain Syndrome
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13 Education:
21 7 BS 2d (Ecology and Evolutionary Biology) c
30 University of Rochester, 2007.
 21 7 MD c
53 State University of New York Downstate College of Medicine, 2011.
 21 9 MSCE 22 (Clinical Epidemiology) c
46 University of Pennsylvania School of Medicine, 2018.
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Description of Clinical Expertise

59 I am a board certified in General Pediatrics and Pediatric Rheumatology.
1ff I have trained expertise in the treatment and management of pediatric chronic, non-inflammatory musculoskeletal pain, including amplified musuculoskeletal pain syndrome (AMPS), juvenile fibromyalgia syndrome and complex regional pain syndrome (CRPS). I serve as Director of the Center for Amplified Musculoskeletal Pain Syndrome at CHOP. In addition, I routinely care for children and young adults with systemic lupus erythematosus, juvenile dermatomyositis, juvenile idiopathic arthritis and enthesitis.
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Description of Research Expertise

327 I am Assistant Professor of Pediatrics and am a pediatric rheumatologist. I received my Master of Science in clinical epidemiology from the University of Pennsylvania. I am an attending physician and medical director of the Center for Amplified Musculoskeletal Pain Syndrome at CHOP and a core faculty member in both the PolicyLab and Center for Clinical Futures at CHOP. I seek to promote, conduct and disseminate research aimed at improving our understanding of the etiologic factors important in the development of chronic non-inflammatory musculoskeletal pain syndromes as well as advance the interdisciplinary treatment strategies for amplified pain to positively impact the lives of youth with chronic pain and their families. My research is funded through a K23 from NIAMS at the NIH.
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Selected Publications

f1 Gmuca et al. : Selection of Core Measures in Development of a Childhood Arthritis and Rheumatology Research Alliance based Pediatric Pain Registry for Management of Amplified Pain Syndrome. 53 Pediatric Research Symposium, Minneapolis, MN March 2026.

 195 Gmuca S, Butler N, Leonard J, Tomlinson AZ, Xiao R, McGill M, Cronholm PF, Young JF, Palermo TM, Rosenberg AR, Weiss PF. : Baseline Characteristics of Adolescents with Amplified Musculoskeletal Pain Syndrome in a Randomized Controlled Trial of Resilience Coaching. US Association for the Study of Pain, Philadelphia, PA March 2026.

 161 Sellars S, Leonard J, Butler N, McGill M, Green S, Miller V, Tomescu O, Sanders R, Gmuca S. : Exploring Menstrual Dysfunction in Adolescents with Amplified Musculoskeletal Pain Syndrome: A Retrospective Review. Society for Adolescent Health and Medicine, Seattle, WA March 2026.

 115 Chern I, Butler N, McGill M, Xiao R, Cronholm PF, Young JF, Palermo TM, Weiss PF, Rosenberg AR, Gmuca S.: Examining Hope in Adolescents with Chronic Musculoskeletal Pain. Children 13(4): 457, March 2026.

 ff Abel D, Butler N, Chatterjee A, Tavlin S, Kellom K, Chang JC, Gmuca S. : A Qualitative Exploration of Adherence to Methotrexate in Juvenile Idiopathic Arthritis. J Pediatr. Jan 2026.

 11e Wells R, McGill M, Gmuca S, Mani A, Sherry DD. : Acute Pain in Children with Chronic Musculoskeletal Pain: A Prospective Controlled Study of Intensive Interdisciplinary Treatment. Children 12(10): 1357, Oct 2025.

 18f Gmuca S, Leonard J, Tomlinson AZ, McGill M, Butler N, Xiao R, Cronholm PR, Palermo TM, Young JF, Rosenberg AR, and Weiss PF. : Identifying Psychosocial Profiles in Youth with Chronic Musculoskeletal Pain: A K-Means Clustering Analysis of Resilience Subgroups. American College of Rheumatology Convergence, Chicago IL Oct 2025.

 131 Shocken DM, Connelly MA, Gmuca S, et al. : Preliminary Findings in the Validation of the Modified Pain and Symptom Assessment Tool in Juvenile Fibromyalgia Syndrome. American College of Rheumatology Convergence, Chicago IL Oct 2025.

 1ab Gmuca S, Leonard J, Tomlinson AZ, McGill M, Butler N, Xiao R, Cronholm PR, Palermo TM, Young JF, Rosenberg AR, and Weiss PF. : Identifying Psychosocial Profiles in Youth with Chronic Musculoskeletal Pain: A K-Means Clustering Analysis of Resilience Subgroups. poster presented at American College of Rheumatology Convergence, Chicago IL. October 2025.

 16e Gmuca S, McGill M, Butler N, Xiao R, Cronholm PF, Young JF, Palermo TM, Weiss PF, Rosenberg AR. : Resilience Coaching for Adolescent Chronic Musculoskeletal Pain: Protocol for a Pilot Randomized Controlled Trial of Promoting Resilience in Stress Management (PRISM). JMIR Res Protoc. Jul 2025.

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