Michael J. LaRiviere, MD

faculty photo
Assistant Professor of Radiation Oncology at the Hospital of the University of Pennsylvania
Attending Physician, Children's Hospital of Philadelphia
Attending Physician - Coverage, Penn Presbyterian Medical Center
Attending Physician - Coverage, Veterans Administration Hospital
Attending Physician - Coverage, Grand View Hospital
Clerkship Director, Radiation Oncology, University of Pennsylvania
Department: Radiation Oncology

Contact information
Perelman Center for Advanced Medicine
3400 Civic Center Blvd., PCAM 2 West
Philadelphia, PA 19104
Office: (215) 615-7239
Education:
BA
Amherst College, 2008.
MD
Emory University School of Medicine, 2015.
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Description of Clinical Expertise

pediatric radiation oncology; lymphoma; leukemia; proton therapy; reirradiation; total body irradiation; total skin electron therapy; stereotactic body radiotherapy

Description of Research Expertise

Dr. Michael J. LaRiviere is an attending radiation oncologist at the Children's Hospital of Philadelphia and the University of Pennsylvania. He did his undergraduate work in neuroscience at Amherst College, medical school at Emory University, and residency at the University of Pennsylvania. He treats pediatric patients and adult patients with hematologic malignancies, using conventional photon radiotherapy, stereotactic body radiotherapy, proton therapy, reirradiation, total skin electron therapy, and total body irradiation. Dr. LaRiviere leads research programs in translational pediatric and hematologic radiation oncology, including preclinical work with FLASH radiotherapy and clinical trials to understand the interactions between immunotherapy and radiation, and chimeric antigen T-cell (CART) therapy and radiation. Dr. LaRiviere has received research funding from the Radiological Society of North America to explore how 3D-printing can be used to improve oncology education for medical students. He is a member of the Children's Oncology Group (COG), International Society of Paediatric Oncology (Société Internationale d'Oncologie Pédiatrique - SIOP), Paediatric Radiation Oncology Society (PROS), International Lymphoma Radiation Oncology Group (ILROG), and University of Pennsylvania Radiation Oncology Quality Assurance/Quality Improvement Committee.

Selected Publications

Yegya-Raman, Nikhil, Plastaras, John P, Wright, Christopher M, Chelius, Monica, Zhang, Siqi, Baron, Jonathan A, Hubbeling, Harper, Sim, Austin J, Robinson, Timothy J, Jain, Michael D: Bridging radiotherapy before chimeric antigen receptor T cells for B-cell lymphomas: an ILROG multicenter study. Blood Advances 9(13): 3293-3303, Jul 2025.

Dreyfuss, AD, Ganesan, N, Imber, BS, LaRiviere, M, Isrow, D, Plastaras, J, Svoboda, J, Yahalom, J, Moskowitz, CH, Moskowitz, A: PEMBROLIZUMAB AND RADIATION THERAPY ALONE AS AN ALTERNATIVE TO TRANSPLANT FOR LOCALIZED FAILURE AFTER CHEMOTHERAPY IN HODGKIN LYMPHOMA: A MULTICENTER PHASE II STUDY. Hematological Oncology 43: e129_70093, Jun 2025.

Elghawy, Omar, Sussman, Jonathan H, Yang, Austin G, Thomas, Colin J, Carter, Jordan S, Landsburg, Daniel J, Svoboda, Jakub, Kim, Ellen, Rook, Alain H, Chung, Jina: Pembrolizumab in Relapsed or Refractory Mycosis Fungoides or Sézary Syndrome. JAMA dermatology 161(6): 656-658, Jun 2025.

Elghawy, Omar, Yang, Austin G, Sussman, Jonathan H, Thomas, Colin J, Carter, Jordan S, Landsburg, Daniel J, Svoboda, Jakub, Kim, Ellen, Rook, Alain H, Chung, Jina: Retrospective cohort study of novel oral agents lenalidomide and duvelisib for relapsed or refractory mycosis fungoides and Sézary syndrome. Journal of the American Academy of Dermatology 92(3): 634-636, Mar 2025.

Zhu, Yifeng, Lu, Baozhu, Byrd, Brook, Chen, Lisha, Xiong, Emily, Plastaras, John P, LaRiviere, Michael, Pogue, Brian W, Zhu, Timothy C: Assessment of generic corrections for multiview Cherenkov emission during total skin electron therapy (TSET). Proc SPIE Int Soc Opt Eng. SPIE, 13299: 24-32, Mar 2025.

Howell, Jackson N, Mark, Bayarmaa, Wada, David A, Bowling, Marianne, Wei, Mei, Lloyd, Shane L, Gaffney, David K, Maity, Amit, LaRiviere, Michael J, Rule, William G: Mental Health Diagnoses in Patients With Mycosis Fungoides and Potential Impact on Oncologic Outcomes. Cancer Medicine 14(5): e70577, Mar 2025.

Hollawell, Casey, Zhang, Siqi, Santos, Alexis Girón, MacDuffie, Emily, Friedes, Cole, Eisenberg, Rachel, Feigenberg, Steven, Konski, Andre, Khullar, Karishma, Maxwell, Russell: Patterns and disparities of proton therapy utilization among adult cancer patients. International Journal of Particle Therapy 15: 100680, Mar 2025.

Jiang C, Kim M, Han X, Chelius M, Hoover T, Kersun L, Reilly AF, Hubbeling H, Cummings E, Kurtz G, Hill-Kayser C, Plastaras JP, LaRiviere MJ: Outcomes of proton therapy to infradiaphragmatic sites in pediatric patients with Hodgkin lymphoma. Pediatric Blood & Cancer 71(12): e31290, Dec 2024.

Kostopoulos N, Costabile F, Krimitza E, Beghi S, Goia D, Perales-Linares R, Thyfronitis G, LaRiviere MJ, Chong EA, Schuster SJ, Maity A, Koumenis C, Plastaras JP, Facciabene A: Local Radiation Enhances Systemic CAR T Cell Efficacy by Augmenting Antigen Cross-Presentation and T-cell Infiltration. Blood Advances 8(24): 6308-6320, Dec 2024.

Dreyfuss A, Ganesan N, Alencar AJ, Boardman AP, Caron P, Chang T, Davey T, David KA, Dogan A, Epstein-Peterson ZD, Falchi L, Fregonese B, Ghione P, Hamlin PA, Horowitz S, Imber BS, Intlekofer AM, Isrow D, Joffe E, Johnson WT, Kumar A, LaRiviere M, Lue JK, Luttwak A, McNicholas M, Moore Z, Munayirji B, Noy A, Owens C, Palomba ML, Patel J, Plastaras JP, Santarosa AM, Schoder H, Shah GL, Steiner RE, Stuver R, Svoboda Jm Torka P, Vardhana SA, Zelenetz AD, Salles G, Yahalom J, Moskowitz CH, Moskowitz A: Pembrolizumab and Involved Site Radiation Therapy Alone As an Alternative to Transplant in Patients with Localized Failure Following Chemotherapy for Hodgkin Lymphoma: A Prospective Multicenter Phase II Study. Blood 144(Suppl1): 4434, Nov 2024 Notes: Poster.

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Last updated: 07/23/2025
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