Heather M Giannini, MD

Adjunct Assistant Professor of Medicine (Pulmonary, Allergy and Critical Care)
Clinical Fellow and Advisor, Penn HealthTech, University of Pennsylvania
Department: Medicine
Education:
BS (Science)
Villanova University, 2008.
MS (Science)
Villanova University, 2009.
MD (Medicine)
Georgetown University School of Medicine, 2015.
MSTR (Translational Research)
University of Pennsylvania, 2022.
Permanent linkBS (Science)
Villanova University, 2008.
MS (Science)
Villanova University, 2009.
MD (Medicine)
Georgetown University School of Medicine, 2015.
MSTR (Translational Research)
University of Pennsylvania, 2022.
Selected Publications
Giannini HM, Lee C, Baston C, Dorgan D.: A Diagnostic Sequence. N Engl J Med. 388(18): 1702-1707, May 2023.Harry-Hernandez S, Thiboutot J, Wahidi MM, Giovacchini CX, De Cardenas J, Meldrum C, Los JG, Illei PB, Shojaee S, Eissenberg T, DiBardino D, Giannini HM, Maldonado F, Roller L, Yarmus LB, Kapp CM. : Bronchoalveolar Lavage (BAL) and Pathologic Assessment of Electronic Cigarette or Vaping Product Use-associated Lung Injury (EVALI): The EVALI-BAL Study, A Multicenter Cohort. J Bronchology Interv Pulmonol. 30(2): 144-154, Apr 2023.
Cosgriff CV, Miano TA, Mathew D, Huang AC, Giannini HM, Kuri-Cervantes L, Pampena MB, Ittner CAG, Weisman AR, Agyekum RS, Dunn TG, Oniyide O, Turner AP, D'Andrea K, Adamski S, Greenplate AR, Anderson BJ, Harhay MO, Jones TK, Reilly JP, Mangalmurti NS, Shashaty MGS, Betts MR, Wherry EJ, Meyer NJ.: Validating a Proteomic Signature of Severe COVID-19. Crit Care Explor 4(12): e0800, Dec 2022.
Giannini, H.M. C. V. Cosgriff, X., B. J. Anderson, T. K. Jones, C. A. G. Ittner, A. R. Weisman, R. Agyekum, T. G. Dunn, T. A. Miano, M. G. Shashaty, C.S. Calfee, P. Sinha, J. P. Reilly, N. J. Meyer. : Immunosuppression may modify performance of biomarker-based ARDS phenotype classifiers. American Thoracic Society 2022 International Conference May 2022 Notes: Poster presentation.
Giannini HM, Meyer NJ. : Genetics of Acute Respiratory Distress Syndrome: Pathways to Precision. Crit Care Clin. 37(4): 817-834, Oct 2021.
Chang SE, Feng A, Meng W, Apostolidis SA, Mack E, Artandi M, Barman L, Bennett K, Chakraborty S, Chang I, Cheung P, Chinthrajah S, Dhingra S, Do E, Finck A, Gaano A, Geßner R, Giannini HM, Gonzalez J, Greib S, Gündisch M, Hsu AR, Kuo A, Manohar M, Mao R, Neeli I, Neubauer A, Oniyide O, Powell AE, Puri R, Renz H, Schapiro J, Weidenbacher PA, Wittman R, Ahuja N, Chung HR, Jagannathan P, James JA, Kim PS, Meyer NJ, Nadeau KC, Radic M, Robinson WH, Singh U, Wang TT, Wherry EJ, Skevaki C, Luning Prak ET, Utz PJ. : New-onset IgG autoantibodies in hospitalized patients with COVID-19. Nat Commun. 12(1): 5417 epub, Sep 2021.
Bange EM, Han NA, Wileyto P, Kim JY, Gouma S, Robinson J, Greenplate AR, Hwee MA, Porterfield F, Owoyemi O, Naik K, Zheng C, Galantino M, Weisman AR, Ittner CAG, Kugler EM, Baxter AE, Oniyide O, Agyekum RS, Dunn TG, Jones TK, Giannini HM, Weirick ME, McAllister CM, Babady NE, Kumar A, Widman AJ, DeWolf S, Boutemine SR, Roberts C, Budzik KR, Tollett S, Wright C, Perloff T, Sun L, Mathew D, Giles JR, Oldridge DA, Wu JE, Alanio C, Adamski S, Garfall AL, Vella LA, Kerr SJ, Cohen JV, Oyer RA, Massa R, Maillard IP, Maxwell KN, Reilly JP, Maslak PG, Vonderheide RH, Wolchok JD, Hensley SE, Wherry EJ, Meyer NJ, DeMichele AM, Vardhana SA, Mamtani R, Huang AC.: CD8+ T cells contribute to survival in patients with COVID-19 and hematologic cancer. Nat Med. 27(7): 1280-1289, Jul 2021.
Giannini, H.M. C. V. Cosgriff, X. M. Lu, B. J. Anderson, T. K. Jones, T. A. Miano, C. A. G. Ittner, A. R. Weisman, R. Agyekum, T. G. Dunn, J. P. Reilly, R. Feng, M. G. Shashaty, N. J. Meyer.: A Whole Blood Transcriptome Signature Implicates Dysregulation of Both Innate and Adaptive Immunity in Septic Shock. American Thoracic Society May 2021 Notes: Poster presentation.
Vella LA, Giles JR, Baxter AE, Oldridge DA, Diorio C, Kuri-Cervantes L, Alanio C, Pampena MB, Wu JE, Chen Z, Huang YJ, Anderson EM, Gouma S, McNerney KO, Chase J, Burudpakdee C, Lee JH, Apostolidis SA, Huang AC, Mathew D, Kuthuru O, Goodwin EC, Weirick ME, Bolton MJ, Arevalo CP, Ramos A, Jasen CJ, Conrey PE, Sayed S, Giannini HM, D'Andrea K, Meyer NJ, Behrens EM, Bassiri H, Hensley SE, Henrickson SE, Teachey DT, Betts MR, Wherry EJ.: Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19. Sci Immunol. 6(57): 1-15, Mar 2021.
Giannini HM, Ginestra JC, Chivers C.: A Machine Learning Algorithm to Predict Severe Sepsis and Septic Shock: Development, Implementation, and Impact on Clinical Practice. Crit Care Med. 47(11): 1485-1492, Mar 2019.