Brooke T Luo, M.D.

faculty photo
Assistant Professor of Clinical Pediatrics (General Pediatrics)
Attending Physician, Pediatric Hospital Medicine, Children's Hospital of Philadelphia
Assistant Professor, University of Pennsylvania, Perelman School of Medicine
Department: Pediatrics

Contact information
Children’s Hospital of Philadelphia
Division of General Pediatrics
Department of Biomedical and Health Informatics
2716 South Street, Floor 15 - 15251
Philadelphia, PA 19146
Office: 267-760-7648
Education:
BSE (Biomedical Engineering)
Duke University Pratt School of Engineering , 2011.
MD
University of Oklahoma College of Medicine, 2015.
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Description of Clinical Expertise

Pediatric Hospitalist
General Pediatrics

Description of Other Expertise

SQL
R, RStudio
Epic Physician Builder Certified
Epic Clinical Data Model Certified by Epic
Biomedical Informatics, Penn Certificate

Description of Research Expertise

Clinical Informatics
Patient Safety Informatics
Data Analytics

Selected Publications

DeChalus A, Luo B, Khan A, Tomlinson AZ, Bonafide C, Ruppel H.: Characterization of Secure Message Use in a Children's Hospital. Hospital Pediatrics 16(1): e18-e23, January 2026.

Ruppel H, Luo B, Won J, Bonafide CP, Albanowski K, DeChalus A, Reed B, Khan AN, Tomlinson AZ, Fu A, Ettore J, Leary M. : Clinician Communication and Patient Safety in Pediatrics: A Practical Application of Human-Centered Design for Problem Identification and Analysis. Journal of Patient Safety 21: S89-S95, October 2025.

Simmons P, Bowen J, Molloy M, Luo B : Secure messaging in medical training: Carving a path for trainee development in the digital age. Journal of Hospital Medicine 20(9): 1015-1017, September 2025.

Kandaswamy S, Knake LA, Dziorny AC, Hernandez SM, McCoy AB, Hess LM, Orenstein E, White MS, Kirkendall ES, Molloy MJ, Hagedorn PA, Muthu N, Murugan A, Beus JM, Mai M, Luo B, Chaparro JD: Pediatric Predictive Artificial Intelligence Implemented in Clinical Practice from 2010 to 2021: A Systematic Review. Applied Clinical Informatics. Chris Lehmann (eds.). 16(3): 477-487, May 2025.

Ruppel H, Khan A, Mintor R, Nguyen J, McNamara M, Luo B, Kelly M, Cato K, Froh EB: Re-designing inpatient nursing notes shared with families: an opportunity to enhance family-centered care delivery. AMIA Annu Symp Proceedings Page: 1249-1257, May 2025.

Ruppel H, Luo B, Rasooly IR, McNamara M, McLoone M, Kern-Goldberger A, Ferro DF, Albanowski K, Brent C, Cieplinski JA, Irizarry J, Rottenberg S, Hehir D, Stinson HR, Makeneni S, Hamershock RA, Won J, Bonafide CP: A systems engineering approach to alarm management on pediatric medical-surgical units. Journal of Hospital Medicine 20(1): 98-103, January 2025.

Molloy MJ, Muthu N, Orenstein EW, Shelov E, Luo BT: Clinical Decision Support Principles for Quality Improvement and Research. Hospital Pediatrics 14(4): 219-224, April 2024.

McLoone M, McNamara M, Jennings MA, Stinson HR, Luo BT, Ferro D, Albanowski K, Ruppel H, Won J, Bonafide CP, Rasooly IR. : Observing sources of system resilience using in situ alarm simulations Journal of Hospital Medicine 18(11): 994-998, November 2023.

Luo BT, Barton HJ, Wooldridge AR, Kelly MM: Human Factors Engineering for the Pediatric Hospitalist. Hospital Pediatrics 13(11): e365–e370, October 2023.

Khan A, Karavite DJ, Muthu N, Shelov E, Nawab U, Desai B, Luo B: Classification of Health Information Technology Safety Events in a Pediatric Tertiary Care Hospital. Journal of Patient Safety 19(4): 251-257, June 2023.

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Last updated: 04/01/2026
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