John V. Bosso, M.D., FAAAAI

faculty photo
Professor of Clinical Otorhinolaryngology: Head and Neck Surgery
Attending Physician, Clinical Professor, Hospital of the University of Pennsylvania
Director, Otorhinolaryngology: HNS Allergy Clinic, Department of Otorhinolaryngolgy: Head and Neck Surgery at the Perelman Center for Advanced Medicine, Hospital of the University of Pennsylvania
Medical Director, Penn AERD Center, Department of Otorhinolaryngology: Head and Neck Surgery at the Perelman Center for Advanced Medicine, Hospital of the University of Pennsylvania
Department: Otorhinolaryngology: Head and Neck Surgery

Contact information
Hospital of the University of Pennsylvania
Perelman Center for Advanced Medicine
South Pavilion, 3rd Floor
3400 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-360-0372
Fax: 215-662-4613
Education:
B.S. (Biochemistry, summa cum laude)
Saint Peter's University, Jersey City, New Jersey, 1981.
M.D. (Medicine)
Jacobs School of Medicine, University at Buffalo, Buffalo, New York, 1985.
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Description of Clinical Expertise

AERD/Samter's Triad
Chronic Rhinosinusitis
Nasal polyps
Aspirin/NSAID Allergy
Aspirin Desensitization
Biologicals for Asthma, CRS, Nasal Polyps
Immunotherapy for Allergic Diseases

Description of Research Expertise

AERD/Samter's Triad
Chronic Rhinosinusitis
Nasal polyps
Aspirin/NSAID Allergy
Aspirin Desensitization
Biologicals for Asthma, CRS, Nasal Polyps
Immunotherapy

Selected Publications

Yu AJ, Phung C, Kuppusamy K, Finuoli AM, Espinosa MC, Douglas JE, Kohanski MA, Adappa ND, Cohen NA, Bosso JV, Palmer JN, Workman AD: The Completeness of Surgery Index Predicts Success in CRSwNP With Asthma by SNOT-22 and Asthma Control Test. Int Forum Allergy Rhinol Oct 2025 Notes: epub ahead of print.

Herpin LP, Finuoli AM, Workman AD, Tang SH, Kuppusamy K, Kohanski MA, Palmer JN, Adappa ND, Douglas JE, Bosso JV: Factors Influencing Aspirin Therapy after Desensitization (ATAD) Tolerance in Aspirin-Exacerbated Respiratory Disease (AERD) Patients Ann Allergy Asthma Immunol 1206(25): 01222-0, Sep 2025.

Douglas JE, Tang SH, Mani A, Palmer JN, Adappa ND, Kohanski MA, Bosso JV: Institutional Experience in Aspirin-Exacerbated Respiratory Disease Yields Favorable Pulmonary and Sinonasal Outcomes. Ear Nose Throat J Jul 2025 Notes: epub ahead of print.

Sell EA, Tan LH, Renner DM, Douglas J, Lee RJ, Kohanski MA, Bosso JV, Kennedy DW, Palmer JN, Adappa ND, Weiss SR, Cohen NA: Common Cold Coronavirus 229E Induces Higher Interferon Stimulating Gene Responses in Human Nasal Epithelial Cells from Patients with Chronic Rhinosinusitis with Polyposis. Am J Rhinol Allergy 39(1): 13-20, Jan 2025.

Asthana S, Workman AD, Lerner DK, Randell RM, Lopez DF, Kohanski MA, Palmer JN, Adappa ND, Douglas JE, Bosso JV: Social factors associated with aspirin desensitization and diagnosis age in aspirin-exacerbated respiratory disease. Int Forum Allergy Rhinol 15(1): 89-92, Jan 2025.

Workman AD, Kuppusamy K, Lerner DK, Bosso JV, Douglas JE, Kohanski MA, Adappa ND, Palmer JN: Assessing adequacy of surgical extent in CRSwNP: The Completion of Surgery Index. Int Forum Allergy Rhinol 15(1): 9-17, Jan 2025.

Jessica Migala: The Little-Known Side Effect of Aspirin Asthma Sufferers Need to Know About AARP Health Online. AARP, April 2024.

Workman Ad, Chang J, Lerner DK, Wilensky J, Montone KT, Bosso JV, Palmer JN, Adappa ND, Kohanski MA: Utilizing Histopathology to Predict Success with Macrolide Therapy in CRS Patients. Laryngoscope 134(3): 1003-1004, Mar 2024.

Kohanski MA, Qatanani A, Lin C, Tan LH, Chang J, Corr A, Herzberg S, Adappa ND, Palmer JN, Reed DR, Bosso JV, Cohen NA: Long-term aspirin desensitization has mucosal cytokine features of immune tolerance. Allergy 79(2): 507-509, Feb 2024.

Buckey TM, Bosso JV: A Stepwise Approach to the adult immunodeficiency evaluation for the rhinologist. Curr Opin Otolaryngol Head Neck Surg 32(1): 50-54, Feb 2024.

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Last updated: 12/12/2025
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