Nikhil Jiwrajka, MD, MS
Instructor A of Medicine (Rheumatology)
Instructor, Division of Rheumatology
Department of Medicine
University of Pennsylvania Perelman School of Medicine
Department: Medicine
Contact information
Division of Rheumatology
5th Floor, White Building, Hospital of the University of Pennsylvania
3400 Spruce Street
Philadelphia, PA 19104
5th Floor, White Building, Hospital of the University of Pennsylvania
3400 Spruce Street
Philadelphia, PA 19104
Education:
BS (Chemistry)
New York University, 2009.
MD (Medicine)
Johns Hopkins University School of Medicine, 2016.
MS (Translational Research)
University of Pennsylvania, 2023.
Permanent linkBS (Chemistry)
New York University, 2009.
MD (Medicine)
Johns Hopkins University School of Medicine, 2016.
MS (Translational Research)
University of Pennsylvania, 2023.
Description of Clinical Expertise
Autoimmune interstitial lung disease, systemic sclerosis (scleroderma), myositis-associated lung diseaseDescription of Research Expertise
Sex differences in immune function, flow cytometry, systemic autoimmunity, autoimmune interstitial lung diseaseSelected Publications
Forsyth KS, Toothacre NE, Jiwrajka N, Driscoll AM, Shallberg LA, Cunningham-Rundles C, Barmettler S, Farmer J, Verbsky J, Routes J, Beiting DP, Romberg N, May MJ, Anguera MC.: Maintenance of X chromosome inactivation after T cell activation requires NF-κB signaling. Sci Immunol 9: eado0398, Oct 2024.Johnson SR, Bernstein EJ, Bolster MB, Chung JH, Danoff SK, George MD, Khanna D, Guyatt G, Mirza RD, Aggarwal R, Allen A Jr, Assassi S, Buckley L, Chami HA, Corwin DS, Dellaripa PF, Domsic RT, Doyle TJ, Falardeau CM, Frech TM, Gibbons FK, Hinchcliff M, Johnson C, Kanne JP, Kim JS, Lim SY, Matson S, McMahan ZH, Merck SJ, Nesbitt K, Scholand MB, Shapiro L, Sharkey CD, Summer R, Varga J, Warrier A, Agarwal SK, Antin-Ozerkis D, Bemiss B, Chowdhary V, Dematte D'Amico JE, Hallowell R, Hinze AM, Injean PA, Jiwrajka N, Joerns EK, Lee JS, Makol A, McDermott GC, Natalini JG, Oldham JM, Saygin D, Lakin KS, Singh N, Solomon JJ, Sparks JA, Turgunbaev M, Vaseer S, Turner A, Uhl S, Ivlev I.: 2023 American College of Rheumatology (ACR)/American College of Chest Physicians (CHEST) Guideline for the Treatment of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Diseases. Arthritis Rheumatol August 2024.
Johnson SR, Bernstein EJ, Bolster MB, Chung JH, Danoff SK, George MD, Khanna D, Guyatt G, Mirza RD, Aggarwal R, Allen A Jr, Assassi S, Buckley L, Chami HA, Corwin DS, Dellaripa PF, Domsic RT, Doyle TJ, Falardeau CM, Frech TM, Gibbons FK, Hinchcliff M, Johnson C, Kanne JP, Kim JS, Lim SY, Matson S, McMahan ZH, Merck SJ, Nesbitt K, Scholand MB, Shapiro L, Sharkey CD, Summer R, Varga J, Warrier A, Agarwal SK, Antin-Ozerkis D, Bemiss B, Chowdhary V, Dematte D'Amico JE, Hallowell R, Hinze AM, Injean PA, Jiwrajka N, Joerns EK, Lee JS, Makol A, McDermott GC, Natalini JG, Oldham JM, Saygin D, Lakin KS, Singh N, Solomon JJ, Sparks JA, Turgunbaev M, Vaseer S, Turner A, Uhl S, Ivlev I.: 2023 American College of Rheumatology (ACR)/American College of Chest Physicians (CHEST) Guideline for the Screening and Monitoring of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Diseases. Arthritis Rheumatol August 2024.
Forsyth KS, Jiwrajka N, Lovell CD, Toothacre NE, Anguera MC.: The conneXion between sex and immune responses. Nat Rev Immunol July 2024.
Lovell CD, Jiwrajka N, Amerman HK, Cancro MP, Anguera MC.: Xist Deletion in B Cells Results in Systemic Lupus Erythematosus Phenotypes. bioRxiv May 2024.
Jiwrajka N, Toothacre NE, Beethem ZT, Sting S, Forsyth KS, Dubin AH, Driscoll A, Stohl W, Anguera MC.: Impaired dynamic X-chromosome inactivation maintenance in T cells is a feature of spontaneous murine SLE that is exacerbated in female-biased models. J Autoimmun July 2023.
Jiwrajka N, Loizidis G, Patterson KC, Kreider ME, Johnson CR, Miller WT Jr, Barbosa EJM Jr, Patel N, Beers MF, Litzky LA, George MD, Porteous MK.: Identification and Prognosis of Patients With Interstitial Pneumonia With Autoimmune Features. J Clin Rheumatol 28: 257-264, Aug 2022.
Jiwrajka N, Anguera MC.: The X in seX-biased immunity and autoimmune rheumatic disease. J Exp Med 219: e20211487, Jun 2022.
Sciurba JC, Gieseck RL, Jiwrajka N, White SD, Karmele EP, Redes J, Vannella KM, Henderson NC, Wynn TA, Hart KM.: Fibroblast-specific integrin-alpha V differentially regulates type 17 and type 2 driven inflammation and fibrosis. J Pathol May 2019.