Jalal Badie Jalaly, MBBS, MS

faculty photo
Associate Professor of Clinical Pathology and Laboratory Medicine
Cytopathology Fellowship Program Director, Penn Medicine (HUP)
Associate Director of Surgical Pathology, Penn Medicine (HUP)
Interim Director of Head and Neck Surgical pathology, Penn Medicine HUP
Department: Pathology and Laboratory Medicine

Contact information
Hospital of the University of Pennsylvania
3400 Spruce Street
6 Founders
Philadelphia, PA 19104
Office: 2156155032
Education:
MBBS (Medicine and Surgery)
College of Medicine, King Saud University, Riyadh, Saudi Arabia, 2009.
MS (Science & Biotechnology)
Albany College of Pharmacy , 2012.
Permanent link
 
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Description of Clinical Expertise

Head and neck, endocrine, and cytopathology

Description of Research Expertise

Oropharyngeal HPV-related squamous cell carcinoma

Selected Publications

Basu D, Sannigrahi MK, Raghav L, Rajagopalan P, Brody R, Jalaly J, Gallant JN: Evidence of a role for oropharyngeal cancer cells with low HPV gene expression in treatment failure. Journal of Clinical Oncology (ASCO) June 2025.

Hieromnimon HM, Trzcinska A, Wen F, Howard FM, Dolezal JM, Dyer E, Kochanny S, Schulte J, Wang C, Chen H, Chin J, …, Jalaly JB, et al: Interpretable HPV detection in head and neck cancer using foundation models and synthetic digital pathology. Cancer Research April 2025.

Sannigrahi MK, Raghav L, Rich DJ, Schrank TP, Califano JA, Lukens JN, Sun L, Morgan IM, Cohen RB, Lin A, Liu X…, Jalaly JB, et al: Tumor-intrinsic and immune-related features associated with treatment failure in human papillomavirus-related oropharyngeal cancer. JNCI: Journal of the National Cancer Institute March 2025.

Hieromnimon HM, Trzcinska A, Wen FT, Howard FM, Dolezal JM, Dyer E, Kochanny S, Schulte JJ, Wang C, Chen H, Chin J, Blair E, Agrawal N, Rosenberg A, Vokes E, Katipally R, Juloori A, Izumchenko E, Lingen MW, Cipriani N, Jalaly JB, Basu D, Riesenfeld SJ, Pearson AT: Analysis of AI foundation model features decodes the histopathologic landscape of HPV-positive head and neck squamous cell carcinomas. Oral Oncology 163, March 2025.

Jalaly JB: MMP11 as a Prognostic Indicator for Inverted Papilloma Histologic Grade and Recurrence. The Laryngoscope 2025.

Rossi ED, Agarwal S, Erkilic S, Hang JF, Jalaly JB, Khanafshar E, Ladenheim A, Baloch Z: Psammoma bodies in thyroid: are they always indicative of malignancy? A multi-institutional study. Virchows Archiv. Springer Berlin Heidelberg, 485, Nov 2024.

Sannigrahi, Malay K.,..., Jalaly JB, et al: Association of oropharyngeal cancer recurrence with tumor-intrinsic and immune-mediated sequelae of reduced genomic instability. bioRxiv Nov 2024.

Resta IT, Jalaly JB: Mucosal neuroma Pathology Outlines 2024.

Tong CCL, Lin X, Seckar T, Koptyra M, Kohanski MA, Cohen NA, Kennedy DW, Adappa ND, Papagiannopoulos P, Kuan EC, Baranov E, Jalaly JB, Feldman MD, Storm PB, Resnick AC, Palmer JN, Wei Z, Robertson ES.: A Metagenomic Analysis of the Virome of Inverted Papilloma and Squamous Cell Carcinoma. Int Forum Allergy Rhinol 13(11): 2055-2062, November 2023 Notes: doi: 10.1002/alr.23182. Epub 2023 May 28.

Jalaly JB, Baloch ZW. : Salivary Gland Neoplasms in Small Biopsies and Fine Needle Aspirations. Semin Diagn Pathol 40(5): 340-348, September 2023 Notes: doi: 10.1053/j.semdp.2023.04.010. Review.

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Last updated: 08/21/2025
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