Ximena Jordan Bruno, MD

faculty photo
Assistant Professor of Clinical Medicine (Hematology-Oncology)
Inherited Predisposition to Hematologic Malignancies Program Development Lead, University of Pennsylvania
Department: Medicine

Contact information
Perelman Center for Advanced Medicine
3400 Civic Center Boulevard
12th Floor
Philadelphia, PA 19104
Education:
MD (Medicine )
Universidad Católica de Córdoba Facultad de Medicina, Republica Argentina, 2001.
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Description of Clinical Expertise

MDS
AML
ALL
MPN
Predisposition syndromes

Description of Research Expertise

germline predisposition syndromes

Selected Publications

Gillett, Sarah R. and Jordan-Bruno, Ximena and Rehman, Hibba and Thomas, Alissa A.: 'Immune-Brain': A Retrospective Review of Cognitive Dysfunction/Decline in Cancer Patients on Checkpoint Inhibitors. SSRN August 2025 Notes: https://ssrn.com/abstract=5340660 or http://dx.doi.org/10.2139/ssrn.5340660.

Xin Wang, Phyllis A. Gimotty, Andrew H. Matthews, Ronac Mamtani, Selina M. Luger, Elizabeth O. Hexner, Daria V. Babushok, Shannon R. McCurdy, Noelle V. Frey, Ximena Jordan Bruno, Saar Gill, Mary Ellen Martin, Vikram R. Paralkar, Ivan Maillard, David L. Porter, Alison W. Loren, Alexander E. Perl, Keith W. Pratz, Kelly D. Getz, Catherine Lai: Evolving racial/ethnic disparities in AML survival in the novel therapy era Blood Adv (2025) 9 (3): 533–544. January 2025.

hannon R. McCurdy, Anthony D Sung, Rebecca T. Brown, Marni Kessler, Nelson J. Chao, Thuy T. Koll, Alfred Fisher, Ernaya Johnson, Meagan Lew, Lauren Bohannon, Sanghee Hong, Pashna Munshi, Saar I. Gill, Nasheed M. Hossain, Sarah Skuli, Noelle V. Frey, Elizabeth O Hexner, Ximena Jordan Bruno, Daria Babushock, Catherine E. Lai, Mary Ellen Martin, Selina M. Luger, David L Porter, Alison W. Loren, Vijaya Raj Bhatt, Phyllis Gimotty: Machine Learning Models Demonstrate Gait Speed As the Best Predictor of Survival and Relapse-Free Survival in Older Adults Undergoing Allogeneic Hematopoietic Cell Transplantation. Transplantation and Cellular Therapy 2025 Notes: https://doi.org/10.1016/j.jtct.2025.01.670.

Ashley D. Hadjis, Honghong Sun, Yangzhu Du, Rebecca T. Brown, Pashna Munshi, Saar I. Gill, Nasheed M. Hossain, Sarah Skuli, Noelle V. Frey, Elizabeth O Hexner, Ximena Jordan Bruno, Catherine E. Lai, Mary Ellen Martin, Selina M. Luger, David L Porter, Alison W. Loren, Shannon R. McCurdy: Graft-Versus-Host Disease (GVHD) and Senescence-Associated Biomarkers Correlate with Frailty and Survival in Older Adults Undergoing Hematopoietic Cell Transplantation (HCT). Transplantation and Cellular Therapy 2025 Notes: https://doi.org/10.1016/j.jtct.2025.01.077.

Rowe M, Babushok D, Carroll M, Carulli A, Frey N, Gill S, Hexner E, Hirsh R, Hossain N, Lai C, Loren A, Luger S, Maillard I, McCurdy S, Matthews A, Martin ME, Paralkar VR, Perl A, Porter D, Pratz K, Stadtmauer E, Bruno XJ.: Tumor Lysis Syndrome in Acute Myeloid Leukemia Patients Treated With a Venetoclax Based Regimen. Eur J Haematol 2025.

Ana I. Velazquez, Carolina Bernabe-Ramirez, Idalid Franco, Cristiane Decat Bergerot, Lauren Kiel, Ximena Jordan Bruno & Narjust Florez: Hispanic/Latinx Representation in the US Physician Workforce In book: Physician Workforce Diversity October 2024.

Matthew P. Connor Neeharika Prathapa Noelle V. Frey Saar I. Gill Elizabeth O. Hexner Ximena Jordan Bruno Catherine E. Lai Alison W. Loren Selina M. Luger Andrew H. Matthews Shannon R. McCurdy Alexander E Perl David L. Porter Arlene Zeringue Joseph H. Oved Timothy S. Olson Keith W. Pratz Daria V. Babushok: Hypomethylating agents are associated with high rates of hematologic toxicity in patients with secondary myeloid neoplasms developing after acquired aplastic anemia April 2024Haematologica DOI: 10.3324/haematol.2024.285275 LicenseCC BY-NC 4.0. Haematologica April 2024 2024.

Margaret Rowe, Daria V Babushok, Martin Carroll, Alison Carulli, Noelle V. Frey, Saar Gill,Elizabeth O Hexner, Rebecca Hirsh, Nasheed Hossain, Catherine Lai, Alison W Loren, Selina M Luger, MD, Ivan Maillard, Shannon R McCurdy, Andrew H Matthews, Mary Ellen Martin, Vikram R Paralkar, Alexander Perl, David L. Porter, Keith W Pratz, Edward A. Stadtmauer, Ximena Jordan Bruno: Comparing Cairo Bishop and Howard Criteria for Identifying Clinically Meaningful Tumor Lysis Syndrome Among Acute Myeloid Leukemia Patients Treated with Venetoclax and Hypomethylating Agents: A Single Center Experience. American Society of Hematology Annual Meeting Dec 2023.

Sindhu Janarthanam Malapati , MD1; Dame Idossa , MD2; Sunny R.K. Singh , MD1; Zihan Wei , MS3; Lauren Kiel , BS3; Fumiko Chino , MD4; Monica Arun Patel , MD5; Ximena Jordan Bruno , MD6; and Narjust Florez , MD3: Parent Penalty: Parental Leave Experiences of Trainees and Early-Career Faculty in Oncology Subspecialties. Journal of Clinical Oncology 19(10): 899-906, Oct 2023.

Andrew H. Matthews, Alexander E. Perl, Selina M. Luger, Saar I. Gill, Catherine Lai, David L. Porter, Sarah Skuli, Ximena Jordan Bruno, Martin P. Carroll, Craig W. Freyer, Alison Carulli, Daria V. Babushok, Noelle V. Frey, Elizabeth O. Hexner, Mary Ellen Martin, Shannon R. McCurdy, Edward A. Stadtmauer, Alison W. Loren, Vikram R. Paralkar, Ivan P. Maillard, Keith W. Pratz: Real world effectiveness of intensive chemotherapy with 7&3 versus venetoclax and hypomethylating agent in acute myeloid leukemia. American Journal of Hematology 98(8): 1254-1264, Aug 2023.

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Last updated: 09/17/2025
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