Catherine Grimes
Adjunct Professor of Biochemistry and Biophysics
Department: Biochemistry and Biophysics
Contact information
University of Delaware
Department of Chemistry & Biochemistry
Newark, DE 19716
Department of Chemistry & Biochemistry
Newark, DE 19716
Office: (302) 831-2985
Lab: (302) 831-2985
Lab: (302) 831-2985
Education:
B.S. (Chemistry with a concentration in Biochemistry)
Villanova University, 2001.
M.S. (Chemistry)
Princeton University, 2002.
Ph.D. (Chemistry)
Harvard University, 2006.
Permanent linkB.S. (Chemistry with a concentration in Biochemistry)
Villanova University, 2001.
M.S. (Chemistry)
Princeton University, 2002.
Ph.D. (Chemistry)
Harvard University, 2006.
Selected Publications
DeMeester Kristen E, Liang Hai, Zhou Junhui, Wodzanowski Kimberly A, Prather Benjamin L, Santiago Cintia C, Grimes Catherine L: Metabolic Incorporation of N-Acetyl Muramic Acid Probes into Bacterial Peptidoglycan. Current protocols in chemical biology 11(4): e74, Dec 2019.Lazor Klare M, Zhou Junhui, DeMeester Kristen E, D'Ambrosio Elizabeth A, Grimes Catherine L: Synthesis and Application of Methyl N,O-Hydroxylamine Muramyl Peptides. Chembiochem : a European journal of chemical biology 20(11): 1369-1375, Jun 2019.
D'Ambrosio Elizabeth A, Drake Walter R, Mashayekh Siavash, Ukaegbu Ophelia I, Brown Ashley R, Grimes Catherine L: Modulation of the NOD-like receptors NOD1 and NOD2: A chemist's perspective. Bioorganic & medicinal chemistry letters 29(10): 1153-1161, May 2019.
Chang Pamela V, Grimes Catherine L: Designer Dendrons To Dissect Innate Immune Signaling. ACS central science 4(8): 948-949, Aug 2018.
McDonald Nathan D, DeMeester Kristen E, Lewis Amanda L, Grimes Catherine Leimkuhler, Boyd E Fidelma: Structural and functional characterization of a modified legionaminic acid involved in glycosylation of a bacterial lipopolysaccharide. The Journal of biological chemistry 293(49): 19113-19126, 12 2018.
Liang Hai, Zhou Guangfeng, Ge Yunhui, D'Ambrosio Elizabeth A, Eidem Tess M, Blanchard Catlyn, Shehatou Cindy, Chatare Vijay K, Dunman Paul M, Valentine Ann M, Voelz Vincent A, Grimes Catherine L, Andrade Rodrigo B: Elucidating the inhibition of peptidoglycan biosynthesis in Staphylococcus aureus by albocycline, a macrolactone isolated from Streptomyces maizeus. Bioorganic & medicinal chemistry 26(12): 3453-3460, 07 2018.
Drake Walter R, Hou Ching-Wen, Zachara Natasha E, Grimes Catherine Leimkuhler: New use for CETSA: monitoring innate immune receptor stability via post-translational modification by OGT. Journal of bioenergetics and biomembranes 50(3): 231-240, 06 2018.
Burch Jason M, Mashayekh Siavash, Wykoff Dennis D, Grimes Catherine L: Bacterial Derived Carbohydrates Bind Cyr1 and Trigger Hyphal Growth in Candida albicans. ACS infectious diseases 4(1): 53-58, 01 2018.
Wang Yiben, Lazor Klare M, DeMeester Kristen E, Liang Hai, Heiss Tyler K, Grimes Catherine L: Postsynthetic Modification of Bacterial Peptidoglycan Using Bioorthogonal N-Acetylcysteamine Analogs and Peptidoglycan O-Acetyltransferase B. Journal of the American Chemical Society 139(39): 13596-13599, 10 2017.
Schaefer Amy K, Wastyk Hannah C, Mohanan Vishnu, Hou Ching-Wen, Lauro Mackenzie L, Melnyk James E, Burch Jason M, Grimes Catherine L: Crohn's Disease Variants of Nod2 Are Stabilized by the Critical Contact Region of Hsp70. Biochemistry 56(34): 4445-4448, 08 2017.