Craig Adam Press, MD, PhD

faculty photo
Associate Professor of Clinical Neurology
Medical Director Neuroscience Unit, CHOP/Neuroscience Center
Physician, Lancaster General Hospital (LGH)
Physician, Hospital of University of Pennsylvania (HUP)
Physician, Pennsylvania Hospital (PAH)
Physician, Chester County Hospital
Physician, Virtua Hospital
Physician, Princeton Healthcare System (PHCS)
Interim Section Head Neurocritical Care Consults, Children's Hospital of Philadelphia
Department: Neurology

Contact information
3401 Civic Center Blvd
Philadelphia, PA 19146
Education:
BS (Biomedical Engineering)
Northwestern University, 2002.
MD, PhD (Medicine, Molecular Biology)
Washington University School of Medicine in St. Louis, 2010.
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Description of Clinical Expertise

Pediatric Neurocritical Care, Pediatric Neurohospitalist Medicine, Pediatric Epilepsy and Critical Care EEG.

Description of Research Expertise

Pediatric Neurocritical Care, Pediatric Epilepsy, Critical Care EEG, Quantitative EEG, Pediatric Neurohospitalist Medicine, Post-Cardiac Arrest Outcomes, Utilizing Big Data for Pediatric Neurology

Selected Publications

Mazzio, Emma, Mistry, Rakesh D., Rosenthal, Scott, Ser, Eileen, Jewell, Jerry, Martin, Jan, Messer, Ricka, Straley, Megan, Leonard, Jan, Press, Craig A.: Neuroimaging for Pediatric Non-First-Time Seizures in the Emergency Department. Neurology: Clinical Practice Page: 10.1212/CPJ.0000000000001165, 2022.

Ackley E, Press CA, Tchou M, Parker S, Dominguez S, Gaensbauer J, Messacar K.: AKI In Suspected Meningitis/Encephalitis May Be “Avoidable Kidney Injury” Hosp. Pediatr 11(8): e167-e169, Aug 2021 Notes: in press.

Press C, Milbrandt J.: Nmnat delays axonal degeneration caused by mitochondrial and oxidative stress. J. Neurosci 28(19): 4861-71, May 2008.

Press C, Milbrandt J.: The purine nucleosides adenosine and guanosine delay axonal degeneration in vitro. J Neurochem 109(2): 595-602, Apr 2009.

Messacar K, Spence-Davizon E, Osborne C, Press C, Schreiner TL, Martin J, et al.: Clinical characteristics of enterovirus A71 neurological disease during an outbreak in children in Colorado, USA, in 2018: an observational cohort study. Lancet Infect Dis 20(2): 230-9, 2020.

Press CA, Kirschen M, LaRovere K, Risen S, Guilliams KP, Chung M, et al.: Variation in Treatment and Outcomes of Children With Acute Disseminated Encephalomyelitis. Hosp Pediatr. 10(2): 159-65, Feb 2020.

O'Brien, N. F., Reuter-Rice, K., Wainwright, M. S., Kaplan, S. L., Appavu, B., Erklauer, J. C., Ghosh, S., Kirschen, M., Kozak, B., Lidsky, K., Lovett, M. E., Mehollin-Ray, A. R., Miles, D. K., Press, C. A., Simon, D. W., Tasker, R. C., LaRovere, K. L.: Practice Recommendations for Transcranial Doppler Ultrasonography in Critically Ill Children in the Pediatric Intensive Care Unit: A Multidisciplinary Expert Consensus Statement. J Pediatr Intensive Care 10(2): 133-142, Jun 2021.

Koh, S., Wirrell, E., Vezzani, A., Nabbout, R., Muscal, E., Kaliakatsos, M., Wickstrom, R., Riviello, J. J., Brunklaus, A., Payne, E., Valentin, A., Wells, E., Carpenter, J. L., Lee, K., Lai, Y. C., Eschbach, K., Press, C. A., Gorman, M., Stredny, C. M., Roche, W., Mangum, T.: Proposal to optimize evaluation and treatment of Febrile infection-related epilepsy syndrome (FIRES): A Report from FIRES workshop. Epilepsia Open 6(1): 62-72, Jan 2021.

Keene, Jennifer C., Morgan, Lindsey A., Abend, Nicholas S., Bates, Sara V., Bauer Huang, Sarah L., Chang, Taeun, Chu, Catherine J., Glass, Hannah C., Massey, Shavonne L., Ostrander, Betsy, Pardo, Andrea C., Press, Craig A., Soul, Janet S., Shellhaas, Renée A., Thomas, Cameron, Natarajan, Niranjana: Treatment of Neonatal Seizures: Comparison of Treatment Pathways From 11 Neonatal Intensive Care Units. Pediatric Neurology 128: 67-74, Mar 2021.

Francoeur, C., Weiss, M. J., Macdonald, J. M., Press, C., Greer, D. M., Berg, R. A., Topjian, A. A., Morrison, W., Kirschen, M. P.: Variability in Pediatric Brain Death Determination Protocols in the United States. Neurology 97(3): e310-e319, Jul 2021.

Press, C. A., Lindsay, A., Stence, N. V., Fenton, L. Z., Bernard, T. J., Mirsky, D. M.: Cavernous Sinus Thrombosis in Children: Imaging Characteristics and Clinical Outcomes. Stroke 46(9): 2657-60, Sept 2015.

Press, C. A., Knupp, K. G., Chapman, K. E.: Parental reporting of response to oral cannabis extracts for treatment of refractory epilepsy. Epilepsy Behav 45: 49-52, Apr 2015.

Kirschen MP, LaRovere K, Balakrishnan B, Erklauer J, Francoeur C, Ganesan S, Jayakar A, Lovett M, Muchette M, Press CA, Wolf M, Ferrazzano P, Wainwright MS, Appavu B: A survey of neuromonitoring practices in North American pediatric intensive care units. Pediatric Neurology 126: 125-130, Jan 2022 Notes: In Press.

Williams, C. N., Hall, T. A., Francoeur, C., Kurz, J., Rasmussen, L., Hartman, M. E., O'Meara A, I., Ferguson, N. M., Fink, E. L., Walker, T., Drury, K., Carpenter, J. L., Erklauer, J., Press, C., Wainwright, M. S., Lovett, M., Dapul, H., Murphy, S., Risen, S., Guerriero, R. M., Woodruff, A., Guilliams, K. P.: Continuing Care For Critically Ill Children Beyond Hospital Discharge: Current State of Follow-up. Hosp Pediatr 12(4): 359-393, Apr 2022.

Benedetti, G. M., Morgan, L. A., Sansevere, A. J., Harrar, D. B., Guerriero, R. M., Wainwright, M. S., LaRovere, K. L., Kielian, A., Ganesan, S. L., Press, C. A., Pediatric Quantitative, E. E. G. Strategic Taskforce: The Spectrum of Quantitative EEG Utilization Across North America: A Cross-Sectional Survey. Pediatr Neurol 141: 1-8, Jan 2023.

Caffarelli M, Karukonda V, Aghaeeaval M, McQuillen PS, Numis AL, Mackay MT, Press CA, Wintermark M, Fox CK, Amorim E; SIPS Investigators.: A quantitative EEG index for the recognition of arterial ischemic stroke in children. Clin Neurophysiol Oct 2023.

Mazzio EL, Topjian AA, Reeder RW, Sutton RM, Morgan RW, Berg RA, Nadkarni VM, Wolfe HA, Graham K, Naim MY, Friess SH, Abend NS, Press CA; ICU-RESUS Eunice Kennedy Shriver National Institute of Child Health; Human Development Collaborative Pediatric Critical Care Research Network Investigator Groups.: Association of EEG characteristics with outcomes following pediatric ICU cardiac arrest: A secondary analysis of the ICU-RESUScitation trial. Resuscitation 201: 110271, Jun 2024.

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Last updated: 09/04/2025
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