Lucy E. Cain, MBBS, MIPH, MMed

faculty photo
Clinical Assistant Professor of Pediatrics (Oncology)
Department: Pediatrics

Contact information
Children's Hospital of Philadelphia
Division of Oncology
3401 Civic Center Blvd.
Philadelphia, PA 19104
Education:
BS (Mathematics)
University of Sydney, 2007.
MBBS
University of Sydney, 2011.
MIPH (International Public Health)
University of Sydney, 2017.
MMed (Genomics and Precision Medicine)
University of Sydney, 2023.
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Selected Publications

Lucy E. Cain, Yimei Li, Hongyan Liu, Regina M. Myers, Allison B Leahy, Diane Baniewicz, Colleen A. Callahan, Amanda DiNofia, Caroline Diorio, Stephen P. Hunger, Kaylyn Utley Lyons, Susan E McClory, Susan R. Rheingold, Mackenzie Stewart, Sarah K Tasian, Lisa Wray, Stephan A. Grupp, Shannon L Maude.: Next Generation Sequencing Minimal Residual Disease in Pediatric B-ALL after CD19 and/or CD22 CAR T-cell Therapy: Depth and Kinetics of Response Predict Relapse Risk. Transplantation and Cellular Therapy, Volume 32, Issue 2, Supplement, 2026, Pages S112-S113 Feb 2026.

Shampavi Sri Haran, Lucy E. Cain, Artur Darmanian, Michael Krivanek, Dale Wright, Wayne Nicholls, Martin Lowe, Luciano Dalla-Pozza, Bruce Goodwin, Jane McEniery, Kevin Hardin, Ashleigh Sullivan, Natacha Omer.: NTRK3 to MET Gene Fusion in Infantile Fibrosarcoma: Response to Crizotinib (in press). New England Journal of Medicine 2026.

Myers RM, Li Y, Liu H, Mumanachit S, Wang L, Leahy AB, Cain LE, DiNofia AM, Diorio C, Freedman JL, Hunger SP, Maude SL, McClory SE, Rheingold SR, Tasian SK, Wray L, Olson TS, Grupp SA, Bunin NJ, Seif AE, Elgarten CW. : Hematopoietic cell transplantation after CD19-directed CAR T-cell therapy for remission consolidation or relapse treatment in pediatric acute lymphoblastic leukemia. Haematologica online ahead of print, Nov 2025.

Lucy Cain, Yimei Li, Anand Bhagwat, Diane Baniewicz, Allison Barz Leahy, Colleen Callahan, Shannon Christensen, Angela Cosey, Amanda DiNofia, Caroline Diorio, Joseph Fraietta, Vanessa Gonzalez, Elizabeth Hexner, Stephen Hunger, Amy Marshall, Shannon Maude, Susan McClory, Regina Myers, Gabriela Plesa, Susan Rheingold, Aakruti Sharma, Mackenzie Stewart, Lisa Wray, Earline Young-Robinson, Stephan Grupp, Saar Gill, Sarah Tasian, Richard Aplenc.: CD123-directed chimeric antigen receptor T-cell (CART123) therapy for relapsed/refractory pediatric acute myeloid leukemia. Blood 2025; 146 (Supplement 1): 1643. Nov 2025.

Cain LE, Mirochnik O, Stevens MM, Kellie SJ, Padhye B, Keogh SJ, Govender D, Ryan J, Dalla-Pozza L, Bateman CM.: Low-Level BCR::ABL1 Transcript at Diagnosis in Childhood Leukemia: A 10-Year Single Institution Study. Genes Chromosomes Cancer. 63(9): e23269, Sep 2024.

Grebstad Tune B, Sareen H, Powter B, Kahana-Edwin S, Cooper A, Koh ES, Lee CS, Po JW, McCowage G, Dexter M, Cain L, O'Neill G, Prior V, Karpelowsky J, Tsoli M, Baumbusch LO, Ziegler D, Roberts TL, DeSouza P, Becker TM, Ma Y: From Pediatric to Adult Brain Cancer: Exploring Histone H3 Mutations in Australian Brain Cancer Patients. Biomedicines 11(11): 2907, Oct 2023.

Lucy E Cain, Katherine Stephen, Vicki Antonenas, Kay Montgomery, Belinda Meares, Melissa A Gabriel.: Haematopoietic progenitor cell mobilisation following blinatumomab therapy in childhood acute lymphoblastic leukaemia. Tandem Meetings. Transplantation & Cellular Therapy Meetings of ASTCT and CIBMTR. Poster Presentation. Orlando, Florida Feb 2023.

Smadar Kahana-Edwin, James Torpy, Lucy E Cain, Anna Mullins, Geoffrey McCowage, Sarah E Woodfield, Sanjeev A Vasudevan, Dan P T Shea, Andre E Minoche, Andres F Espinoza, Sarah Kummerfeld, Leonard D Goldstein, Jonathan Karpelowsky: Quantitative ctDNA Detection in Hepatoblastoma: Implications for Precision Medicine. Cancers (Basel) 16(1): 12, Jan 2023.

L. Cain: "C-circle testing as an 'ALT'ernative liquid biopsy approach for osteosarcoma." Poster presented at: Australia and New Zealand Sarcoma Association Annual Scientific Meeting. Sydney, Queenstown. 2022 Choong-Dickinson Poster Prize Award. Australia and New Zealand Sarcoma Association Annual Scientific Meeting. Sydney, Australia and Queenstown, New Zealand. 2022 Choong-Dickinson Poster Prize Award Nov 2022.

L. Cain: Accessing donors in a geographically isolated country during the COVID-19 pandemic. The Australian and New Zealand Children's Haematology/Oncology Group (ANZCHOG) Annual Scientific Meeting. Poster Presentation. Sydney, Australia July 2022.

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Last updated: 03/22/2026
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