Nikhil Pai, BSc, MD

Associate Professor of Pediatrics (Gastroenterology, Hepatology and Nutrition) at the Children's Hospital of Philadelphia
Member, Research Institute, Children's Hospital of Philadelphia
Member, Institute for Translational Medicine and Therapeutics, University of Pennsylvania School of Medicine
Member, Metabolism, Nutrition and Physical Development Research Affinity Group, Children's Hospital of Philadelphia
Department: Pediatrics
Contact information
Children's Hospital of Philadelphia
Division of Gastroenterology, Hepatology and Nutrition
Roberts Center for Pediatric Research
2716 South Street, Room 14321
Philadelphia, PA 19146
Division of Gastroenterology, Hepatology and Nutrition
Roberts Center for Pediatric Research
2716 South Street, Room 14321
Philadelphia, PA 19146
Office: 215-590-2997
Fax: 215-590-2799
Fax: 215-590-2799
Publications
Education:
BSc (Biology,)
University of Western Ontario, 2004.
MD (Medicine,)
McMaster University, 2007.
Residency (Pediatrics,)
Hospital for Sick Children (University of Toronto), 2011.
Fellowship (Pediatric Gastroenterology, Hepatology & Nutrition,)
Boston Children's Hospital (Harvard Medical School), 2014.
Permanent linkBSc (Biology,)
University of Western Ontario, 2004.
MD (Medicine,)
McMaster University, 2007.
Residency (Pediatrics,)
Hospital for Sick Children (University of Toronto), 2011.
Fellowship (Pediatric Gastroenterology, Hepatology & Nutrition,)
Boston Children's Hospital (Harvard Medical School), 2014.
Selected Publications
Pai N, Popov J, Hill L, Hartung E, Grzywacz K, Moayyedi P; McMaster Pediatric Fecal Microbiota Transplant Research Collaboration.: Results of the first pilot randomized controlled trial of fecal microbiota transplant in pediatric ulcerative colitis: Lessons, limitations, and future prospects. Gastroenterology 161(2): 388-393.e3, Aug 2021.Popov J, Hartung E, Hill L, Chauhan U, Pai N.: Pediatric patient and parent perceptions of fecal microbiota transplantation for the treatment of ulcerative colitis. J Pediatr Gastroenterol Nutr 73(6): 684-688, Dec 2021.
Yamamoto M, Shanmuganathan M, Hart L, Pai N, Britz-McKibbin P: Urinary metabolites enable differential diagnosis and therapeutic monitoring of pediatric inflammatory bowel disease. Metabolites 11(4): 245, Apr 2021.
Lemay JA, Yamamoto M, Kroezen Z, Shanmuganathan M, Ly R, Hart L, Pai N, Britz-McKibbin P.: Lyophilized fecal short-chain fatty acid and electrolyte determination by capillary electrophoresis with indirect UV detection for assessment of pediatric inflammatory bowel disease. J Pharm Biomed Anal 192: 113658, Jan 2021.
Popov J, Caputi V, Nandeesha N, Rodriguez DA, Pai N.: Microbiota-immune interactions in ulcerative colitis and colitis associated cancer and emerging microbiota-based therapies. Int J Mol Sci 22(21): 11365, Oct 2021.
Pai N, Popov J, Hill L, Hartung E.: Protocol for a double-blind, randomised, placebo-controlled pilot study for assessing the feasibility and efficacy of faecal microbiota transplant in a paediatric Crohn's disease population: PediCRaFT Trial. BMJ Open 9(11): e030120, Nov 2019.
Quirt J, Belza C, Pai N, Clause RF, Markovic F, Wong-Sterling S, Avitzur Y, Wales PW.: Reduction of central line-associated bloodstream infections and line occlusions in pediatric intestinal failure patients receiving long-term parenteral nutrition using an alternative locking solution, 4% Tetrasodium ethylenediamine-tetraacetic acid. JPEN J Parenter Enteral Nutr 45(6): 1286-92, Aug 2021.
Nieuwdorp M, Gilijamse PW, Pai N, Kaplan LM.: Role of the microbiome in energy regulation and metabolism. Gastroenterology 146(6): 1525-33, May 2014.
Wang AY, Popov J, Pai N.: Fecal microbial transplant for the treatment of pediatric inflammatory bowel disease. World J Gastroenterol 22(47): 10304-10315, Dec 2016.
Pai N, Margolis KG: The microbiome in early biomarker discovery for neurodevelopmental disorders: A novel research roadmap? Gastroenterology(4), 813-4, August 2024.