Grace Chan, MD, MPH, PhD
Associate Professor of Pediatrics (General Pediatrics)
Department: Pediatrics
Contact information
Children's Hospital of Philadelphia
2716 South Street
Philadelphia, PA 19146
2716 South Street
Philadelphia, PA 19146
Office: +1-267-425-5832
Education:
AB (Biology and Psychology)
Harvard University, 2001.
MPH (Epidemiology and Biostatistics)
Johns Hopkins University School of Public Health, 2006.
MD
Harvard University Medical School, 2007.
PhD (Clinical Investigation)
Johns Hopkins University School of Public Health, 2013.
Permanent linkAB (Biology and Psychology)
Harvard University, 2001.
MPH (Epidemiology and Biostatistics)
Johns Hopkins University School of Public Health, 2006.
MD
Harvard University Medical School, 2007.
PhD (Clinical Investigation)
Johns Hopkins University School of Public Health, 2013.
Description of Research Expertise
Dr. Chan is a physician-scientist with expertise in epidemiology and public health. Her research aims to improve child health by using epidemiologic methods to discover and deliver evidence-based interventions. She is motivated by the need to reduce child morbidity and mortality in settings where populations have the highest burden of disease yet the least data, research, and programs. Her work focuses on surveillance of child morbidity and mortality to improve disease estimates, risk prediction for preterm birth and antenatal care attendance, maternal and neonatal infections and antimicrobial resistance, and development and testing of interventions to improve birth outcomes, survival, and well-being of infants and children. She has partnered with community-based organizations, government agencies, and the World Health Organization to discover and deliver cost-effective interventions for vulnerable populations.Selected Publications
Taddesse L, Korte ML, Hunegnaw BM, Teklie H, Bekele D, Tolera G, Zelalem M, Chan GJ: Setting a research agenda to advance maternal, newborn, and child health in Ethiopia: An adapted CHNRI prioritization exercise. J Glob Health Feb 2025 Notes: doi 10.7189/13.04010Thompson E, Kassa GM, Fite RO, Pons-Duran C, Goddard FG, Worku A, Haneuse S, Hunegnaw BM, Bekele D, Alemu K, Taddesse L, Chan GJ: Birth outcomes and survival by sex among newborns and children under two in the Birhan Cohort: a prospective cohort study in the Amhara Region of Ethiopia. BMJ Global Health 9(8): e015475, August 2024.
Chan GJ, Murray M, Zelelam M: Azithromycin to Prevent Sepsis or Death in Women Planning a Vaginal Birth. N Engl J Med 389(3): 282, July 2023 Notes: doi: 10.1056/NEJMc2305875.
Wilder B, Pons-Duran C, Goddard FGB, Hunegnaw BM, Haneuse S, Bekele D, Chan GJ: Development of Prediction Models for Antenatal Care Attendance in Amhara Region, Ethiopia. JAMA Network Open 6(5): e2315985, May 2023 Notes: doi:10.100l/jamanetworkopen.2023.15985.
Carvalho MJ*, Sands K*, Thomson K, Portal E, Mathias J, Milton R, Gillespie D, Dyer C, Akpulu C, Boostrom I, Hogan P, Saif H, Ferreira A, Nieto M, Hender T, Hood K, Andrews R, Watkins JW, Hassan B, Chan G, Bekele D, Solomon S, Metaferia G, Basu S, Naha S, Sinha A, Chakravorty P, Mukherjee S, Iregbu K, Modibbo F, Uwaezuoke S, Audu L, Edwin CP, Yusuf AH, Adeleye A, Mukkadas AS, Zahra R, Shirazi H, Muhammad A, Ullah S, Jan MH, Akif S, Mazarati JB, Rucogoza A, Gaju L, Mehtar S, Bulabula ANH, Whitelaw A, Roberts L; BARNARDS Group; Walsh TR: Antibiotic resistance genes in the gut microbiota of mothers and linked neonates with or without sepsis from low- and middle-income countries. Nat Microbiol 7(9): 1337-1347, September 2022 Notes: doi: 10.1038/s41564-022-01184-y. Epub 2022 Aug 4.
Chan GJ, Goddard FGB, Hunegnaw BM, Mohammed Y, Hunegnaw M, Haneuse S, Bekele C, Bekele D: Estimates of stillbirths, neonatal mortality, and vulnerable live births in Amhara, Ethiopia. JAMA Network Open 5(6): e2218534, June 2022 Notes: doi:10.1001/jamanetworkopen.2022.18534.
Milton R, Gillespie D, Dyer C, Taiyari K, Carvalho MJ, Thomson K, Sands K, Portal EAR, Flood K, Ferreira A, Hender T, Kirby N, Mathias J, Nieto M, Watkins WJ, Bekele D, Abayneh M, Solomon S, Basu S, Nandy RK, Saha B, Iregbu K, Modibbo F, Uwaezuoke S, Zahra R, Shirazi H, Najeeb S, Mazarati JB, Rucogoza A, Gaju L, Mehtar S, Bulabula ANH, Whitelaw A, Walsh TR, BARNARDS Group, Chan GJ. : Neonatal sepsis and mortality in low- and middle-income countries from a facility based birth cohort: an international multi-site prospective observational study. Lancet Glob Health 10(5): e661-e672, May 2022 Notes: doi: 10.1016/S2214-109X(22)00043-2.
Bekele D, Hunegnaw BM, Bekele C, Van Wickle K, Tadesse F, Goddard FGB, Mohammed Y, Unninayar S, Chan GJ: Cohort profile: the Birhan Health and Demographic Surveillance System. Int J Epidemiol 51(2): e39-e45, May 2022 Notes: doi: 10.1093/ije/dyab225.
Sands K, Carvalho MJ, Portal E, Thomson K, Dyer C, Akpulu C, Andrews R, Ferreira A, Gillespie D, Hender T, Hood K, Mathias J, Milton R, Nieto M, Taiyari K, Chan GJ, Bekele D, Solomon S, Basu S, Chattopadhyay P, Mukherjee S, Iregbu K, Modibbo F, Uwaezuoke S, Zahra R, Shirazi H, Muhammad A, Mazarati JB, Rucogoza A, Gaju L, Mehtar S, Bulabula ANH, Whitelaw A, BARNARDS Group, Walsh TR: Characterization of antimicrobial-resistant Gram-negative bacteria that cause neonatal sepsis in seven low- and middle-income countries. Nat Microbiol 6(4): 512-523, April 2021 Notes: doi: 10.1038/s41564-021-00870-7.
Boundy EO, Spiegelman D, Fawzi WW, Lieberman E, Missmer SA, Dastjerdi R, Kajeepeta S, Wall S, Chan GJ: Kangaroo Mother Care and Neonatal Outcomes: A Systematic Review and Meta-Analysis. Pediatrics 137(1): e20152238, January 2016 Notes: doi: 10.1542/peds.2015-2238. Epub 2015 Dec 23.