Selina M. Luger, M.D., FRCPC

faculty photo
Professor of Medicine at the Hospital of the University of Pennsylvania
Department: Medicine

Contact information
Division of Hematology Oncology
Perelman Center for Advanced Medicine
12th Floor, South Pavilion
Office #12-157
34th and Civic Center Blvd
Philadelphia, PA 19104
Office: 215-614-1847
Fax: 215-615-5888
A.B. (Biochemistry)
Harvard University, 1982.
M.D.CM (Medicine)
McGill University, 1987.
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Description of Research Expertise

Leukemia, myelodysplastic syndrome, myeloproliferative disorders

Description of Clinical Expertise

hematologic malignancies, leukemia, AML, ALL, CML, myelodysplastic syndrome, MDS, myeloproliferative disorders, stem cell transplantation, bone marrow transplant

Selected Publications

Shallis Rory M, Stahl Maximilian, Wei Wei, Montesinos Pau, Lengline Etienne, Neukirchen Judith, Bhatt Vijaya R, Sekeres Mikkael A, Fathi Amir T, Konig Heiko, Luger Selina, Khan Irum, Roboz Gail J, Cluzeau Thomas, Martínez-Cuadron David, Raffoux Emmanuel, Germing Ulrich, Umakanthan Jayadev Manikkam, Mukhereje Sudipto, Brunner Andrew M, Miller Adam, McMahon Christine M, Ritchie Ellen K, Rodríguez-Veiga Rebeca, Itzykson Raphaël, Boluda Blanca, Rabian Florence, Tormo Mar, Acuña-Cruz Evelyn, Rabinovich Emma, Yoo Brendan, Cano Isabel, Podoltsev Nikolai A, Bewersdorf Jan Philipp, Gore Steven, Zeidan Amer M: Patterns of care and clinical outcomes of patients with newly diagnosed acute myeloid leukemia presenting with hyperleukocytosis who do not receive intensive chemotherapy. Leukemia & lymphoma Page: 1-6, Feb 2020.

Velu PD, Perl AE, Luger SM, Bagg A, Morrissette JJD.: Longitudinal targeted next-generation sequencing in a patient with acute myeloid leukaemia. Br J Haematol. Jun 17 2019 Notes: Epub ahead of print.

McMahon CM, Ferng T, Canaani J, Wang ES, Morrissette JJ, Eastburn DJ, Pellegrino M, Durruthy-Durruthy R, Watt CD, Asthana S, Lasater EA, DeFilippis R, Peretz CAC, McGary LHF, Deihimi S, Logan AC, Luger SM, Shah NP, Carroll M, Smith CC, Perl AE.: Clonal selection with Ras pathway activation mediates secondary clinical resistance to selective FLT3 inhibition in acute myeloid leukemia. Cancer Discov May 14 2019 Notes: Epub ahead or print.

Stock W, Luger SM, Advani AS, Yin J, Harvey RC, Mullighan CG, Willman CL, Fulton N, Laumann KM, Malnassy G, Paietta E, Parker E, Geyer S, Mrózek K, Bloomfield CD, Sanford B, Marcucci G, Liedtke M, Claxton DF, Foster MC, Bogart JA, Grecula JC, Appelbaum FR, Erba H, Litzow MR, Tallman MS, Stone RM, Larson RA.: A pediatric regimen for older adolescents and young adults with acute lymphoblastic leukemia: results of CALGB 10403. Blood. 133(14): 1548-1559, Apr 4 2019.

McMahon CM, Luger SM.: Relapsed T Cell ALL: Current Approaches and New Directions. Curr Hematol Malig Rep 14(2): 83-93, Apr 2019.

McMahon CM, Luger SM.: Maintenance therapy in acute myeloid leukemia: What is the future? Semin Hematol. 56(2): 102-109, Apr 2019.

Medeiros BC, Othus M, Tallman MS, Sun Z, Fernandez HF, Rowe JM, Lazarus HM, Appelbaum FR, Luger SM, Litzow MR, Erba HP.: The relationship between clinical trial accrual volume and outcomes in acute myeloid leukemia: A SWOG/ECOG-ACRIN study (S0106 and E1900). Leuk Res 78: 29-33, Mar 2019.

Ganetsky A, Frey NV, Hexner EO, Loren AW, Gill SI, Luger SM, Mangan JK, Martin ME, Babushok DV, Drobyski WR, Smith J, Timlin C, Freyer CW, Stadtmauer EA, Porter DL.: Tocilizumab for the treatment of severe steroid-refractory acute graft-versus-host disease of the lower gastrointestinal tract. Bone Marrow Transplant. 54(2): 212-217. Feb 2019.

Litzow MR, Wang XV, Carroll MP, Karp JE, Ketterling RP, Zhang Y, Kaufmann SH, Lazarus HM, Luger SM, Paietta EM, Pratz KW, Tun HW, Altman JK, Broun ER, Rybka WB, Rowe JM, Tallman MS.: A randomized trial of three novel regimens for recurrent acute myeloid leukemia demonstrates the continuing challenge of treating this difficult disease. Am J Hematol 94(1): 111-117, Jan 2019.

Fernandez HF, Sun Z, Litzow MR, Luger SM, Paietta E, Racevskis J, Levine RL, Patel JP, Abdel-Wahab O, Ketterling RP, Dewald GW, Bennett JM, Rowe JM, Lazarus HM, Tallman MS.: Extramedullary acute myeloid leukemia presenting in young adults demonstrates sensitivity to high dose anthracycline: subset analysis from ECOG-ACRIN 1900. Haematologica Nov 2018 Notes: Epub ahead of print.

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Last updated: 04/06/2020
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