Epigenetics at the intersection of cancer, immunity, and metabolism
The Capell Lab seeks to answer fundamental questions regarding how epigenetic processes (histone, RNA, DNA) are impacted by intrinsic (i.e. aging, sex chromosomes) and extrinsic (i.e. ultraviolet radiation, diet, etc.) environmental influences, and how these changes impact cellular homeostasis (i.e. metabolism, immunity) to promote epithelial diseases such as cancer.
By combining innovative in vivo models and human patient samples with the most cutting-edge epigenetic approaches, we aim to identify therapeutic vulnerabilities and novel targets to treat disease.
We invite you to explore our website to learn more about our research program and its members.