Penn Cardiovascular Institute (CVI)
Congratulations to Marielle Scherrer-Crosbie on her feature in Penn Medicine News!
Patients with acute lymphoblastic leukemia or acute myeloid leukemia who 
are treated with anthracyclines are at a heightened risk of heart failure — often within one year of exposure to the chemotherapy treatment, according to a new study led by Marielle Scherrer-Crosbie, MD, PhD, director of the Cardiac Ultrasound Laboratory and a professor of Cardiovascular Medicine. To identify a patient’s risk for heart failure following the treatment, researchers developed a risk score based on clinical and echographic variables.
See also Cardiology Today, AJMC Newsroom, and News-Medical.net
Stanford-Penn Symposium 2019 Photos
View some images from the Stanford-Penn Symposium in November 2019
Congratulations to Winners at the Northwestern Cardiovascular Young Investigators' Forum!
Junior Faculty (Clinical) Winner of the Jeremiah Stamler Award:
Payman Zamani, MD, MTR
"Impaired Skeletal Muscle Oxidative Capacity in HFpEF"
Fellows (Basic Science) 2nd Place:
Eliot Graham Peyster, MD, MSc
"In-situ Immune Profiling of Heart Transplant Biopsies to Improve Diagnostic Accuracy and Rejection Risk Stratification"
Junior Faculty (Basic Science) 1st Place:
Marie Guerraty, MD, PhD
"Friend of GATA 2 (FOG2/ZFPM2) is Associated with Coronary Microvascular Disease and Mediates Hypoxia-inducible Factor (HIF) Angiogenic Gene Expression"
Stanford-Penn Cardiovascular Symposium
Featuring: Daniel Kelly, MD; Saman Nazarian, MD, PhD; Thomas Cappola, MD, ScM; Bonnie Ky, MD, MSCE; Daniel Rader, MD; Rajan Jain, MD; Kiran Musunuru, MD, PhD, MPH; Zoltan Arany MD, PhD; Scott Damrauer, MD.
November 4-5, 2019 – Stanford, California
"Failure of Mitochondrial Control Causes Heart Disease"
This study reveals that a well-known protein, ANT, participates in mitophagy; mutations in the genes of that protein suppress mitophagy and cause disease.
~ Penn Medicine News
Zoltan Arany, M.D., Ph.D.
Found in Nature, Oct 16, 2019
"Targeting cardiac fibrosis with engineered T cells"
Jonathan Epstein, Ph.D., Rajan Jain, M.D., and Kenneth Margulies, M.D.
Congratulations to Drs. Rajan Jain and Arjun Raj!
Recipients of the 2019 NIH Director's Transformative Research Award!
“Cardiac Genetic Mutation May Not Always Predict Heart Disease”
Zoltan Arany, M.D., Ph.D.
Researchers at Penn Medicine and Geisinger find only 5 percent of patients with a mutation of the TTN gene have dilated cardiomyopathy, despite changes in heart function
~ Penn Medicine News
Circulation. 2019 Jul 2;140(1):42-54
Congratulations to Dr. Zoltan Arany for his election to Association of American Physicians (AAP)!
Zoltan Arany, M.D., Ph.D.
Professor of Medicine
Director, Cardiovascular Metabolism Program
Penn Cardiovascular Institute, Perelman School of Medicine
Posted: April 5, 2019
Congratulations to Bonnie Ky for her Editorship with JACC CardioOncology!
The American College of Cardiology (ACC) will expand the JACC family of journals with the launch of JACC: CardioOncology in September 2019. Bonnie Ky, MD, MSCE, FACC, will serve as Editor-in-Chief.
~ JACC: CardioOncology – Launching in September 2019
Congratulations to Rajat Deo and Kenneth Margulies on their published Op-Ed!
Coronary artery disease is the most common risk factor linked to sudden cardiac death. Yet, questions exist about why some people are more likely to die suddenly than others who have the same medical condition.
~ Understanding Who's at Risk for Sudden Cardiac Death Published in The Inquirer
Congratulations to Dr. Kiran Musunuru for Receiving the AFMR 2019 Outstanding Investigator Award!
An Outstanding Investigator Award is presented annually to an AFMR member in recognition of excellence in biomedical research.
~AFMR
New Heart Valve Modeling Technique Enables Customized Medical Care for Patients
Robert Gorman, M.D.
Professor of Surgery
Perelman School of Medicine
“Cardiac surgeons must decide upon the best possible treatment for heart valve repair without knowing all the facts,” said Dr. Robert Gorman, professor of surgery in the Perelman School of Medicine at the University of Pennsylvania and a key collaborator on the study. “Most rely on their own experiences or how they were taught to perform valve repair surgery in medical school.”
~ University of Texas at Austin News
Congratulations to Drs. Rajan Jain, Mark Kahn, and Zoltan Arany for receiving the AHA-Allen Award!
Rajan Jain, M.D.
Assistant Professor of Medicine
Perelman School of Medicine
Mark Kahn, M.D.
Cooper-McLure Professor of Medicine
Director, Center for Vascular Biology
Penn Cardiovascular Institute, Perelman School of Medicine
Zoltan Arany, M.D., Ph.D.
Professor of Medicine
Director, Cardiovascular Metabolism Program
Penn Cardiovascular Institute, Perelman School of Medicine
~ The American Heart Association
Posted: November 13, 2018
Congratulations to Dr. Zoltan Arany for his election to a Fellow of ISHR!
Zoltan Arany, M.D., Ph.D.
Professor of Medicine
Director, Cardiovascular Metabolism Program
Penn Cardiovascular Institute, Perelman School of Medicine
See: ISHR World Newsletter pg. 13
Posted: November 13, 2018
Congratulations to Dr. Kiran Musunuru for Receiving the 2018 Judson Daland Prize!
Kiran Musunuru, M.D. Ph,D., M.P.H.
Associate Professor; Director
Genetic and Epigenetic Origins of
Disease Program, Cardiovascular
Institute, Perelman School of Medicine
"The prize was presented to Kiran Musunuru at the American Philosophical Society 2018 November Meeting, in recognition of his work discovering and therapeutically targeting cardiovascular disease genes."
~The American Philosophical Society
Posted: June 5, 2018
Congratulations to Dr. Rajan Jain for Receiving a New Innovator NIH Director's Award!
Rajan Jain, M.D.
Assistant Professor of Medicine
Perelman School of Medicine
"Rajan Jain, MD, an assistant professor of Medicine and Cell and Developmental Biology and member of the Cardiovascular Institute (CVI) and Institute for Regenerative Medicine (IRM), will be provided $2.4 million to advance understanding how cell identity is established and maintained. This generous support will help his group decode the rules that instruct genome organization and cellular identity, ultimately revealing implications for human disease."
~Penn Medicine News
Dr. Kiran Musunuru Testifying in the US Senate:
Dr. Musunuru briefing staff members of the U.S. Senate Committee on Health, Education, Labor and Pensions about genomic medicine and gene editing on September 28, 2018, in Washington, DC, as a representative of the American Society of Human Genetics.
Photo credits: Ann Klinck.