2019
Preventing Dangerous Blood Clots
Development and Clinical Testing of a New Device to Prevent DVT
Team Leader:
Mark Kahn
Using Blood Cells as Drug “Couriers” to Fight Stroke
Synergizing Drug-Loaded Nanocarriers with Endovascular Thrombectomy for Treatment of Ischemic Stroke
Team Leaders:
Vlad Muzykantov
Jake Brenner
2020
Gene Therapy for Muscular Dystrophy
Synergistic Upregulation and Replacement of Utrophin as a Novel Therapy for Cardiac and Pulmonary Patho-Physiology in DMD
Team Leader:
Hansell Stedman
Video-guided Ablation of Cardiac Arrhythmias
Synergizing Drug-Loaded Nanocarriers with Endovascular Thrombectomy for Treatment of Ischemic Stroke
Team Leader:
Saman Nazarian
2021
CVI COVID-19 Translational Dream Teams (Special RFA)
Assessment of Cardiac Conduction and Dysautonomia in a post-COVID Long-Haul Cohort
Team Leader:
Rajat Deo
The Role of COVID-induced Coronary Microvascular Disease in Long-Hauler Syndrome
Team Leader:
Marie Guerraty
Mouse Genetic Investigation of COVID-19 Cardiovascular Disease
Team Leader:
Mark Kahn
2024
How do SGLT2 Inhibitors Treat Heart Failure?
Making a better SGLT2 inhibitor to treat heart failure
Team Leader:
Zoltan Arany
Co-I:
Greg Bowman
Cargo-carrying Nanoparticles to target Cardiovascular Disease
Engineering antibody-tethered lipid nanoparticles to treat cardiovascular diseases
Team Leaders:
Noor Momin
Michael Mitchell
2025
Prenatal and perinatal LNP-mediated gene editing in the heart to treat myocardial diseases
Team Leaders:
Kiran Musunuru
William Peranteau
Development of a portable stroke detector for large vessel occlusion
Team Leaders:
Christopher Favilla
Wesley Baker
DNA-loaded lipid nanoparticles (DNA-LNPs): a new platform technology for vascular diseases
Team Leaders:
Jacob Brenner
David Frank
OxLDL-targeted Chimeric Antigen Receptor T Regulatory Cells to Reduce Atherosclerosis
Team Leaders:
Avery Posey, Jr.
Daniel Rader
