Welcome to the Kahn Lab
Our lab investigates signaling pathways that regulate cardiovascular biology and diseases. We are interested in both lymphatic and blood vessel regulatory pathways, and in the interactions between blood cells and vascular endothelium. Most of the pathways we investigate are known to cause human vascular diseases. We apply vertebrate genetic approaches as well as biochemical and state of the art molecular approaches to understand the function of these pathways during normal development and in disease models.
Congratulations to Alan Tang, MD/PhD candidate, on receiving the 2017 Kaushal Family Awards in Genetics!
Read about Dr. Kahn and Lauren Goddard Raines' research in Cell Press… "Hemodynamic Forces Sculpt Developing Heart Valves through a KLF2-WNT9B Paracrine Signaling Axis".
Read about Dr. Kahn and Alan Tang's research into CCM disease in the NY Times..."A Baffling Brain Defect Is Linked to Gut Bacteria, Scientists Say" by Gina Kolata.
Just Published in Nature! Endothelial TLR4 and the microbiome drive cerebral cavernous malformations.
We are currently accepting post-doctoral research fellow applications.
Penn Study Describes the Molecular Cause of Common Cerebrovascular Disease