Alexandra Farran, Ph.D.
Post-Doctoral Fellow
University of Pennsylvania
Hometown
Rouen, France
Education
Ph.D. Materials Science and Engineering, 2012, University of Delaware
M.S. Chemistry, 2005, National Graduate Chemistry School of Mulhouse (ENSCMu), France
B.S. Chemistry, 2003, National Graduate Chemistry School of Mulhouse (ENSCMu), France
Areas of Special Interest
During my Ph.D, my research was focused on developing hydrogels and bioreactors for vocal fold tissue engineering. Now my research is focused on studying the effect of growth factors and mechanical stimulations on chondrocytes for cartilage repair purposes. In my spare time I enjoy cooking, traveling, and spending time with my family.
Awards
2011 Materials Science and Engineering Chairperson's Outstanding Graduate Student Award
Patents
Jia, X.; Jia, M.; Jha, A. K.; Farran, A. J. E.; Tong, Z. "Dynamic Vibrational Method and Device for Vocal Fold Tissue Growth" Nonprovisional Patent Application, US 20100291045, May 15, 2010
Publications
Teller, S. S.*; Farran, A. J. E.*; Xiao, L.; Jiao, T.; Duncan, R.L.; Clifton, R. J.; Jia, X. "High Frequency Viscoelastic Shear Properties of Vocal Fold Tissues: Implications for Vocal Fold Tissue Engineering", Tissue Engineering: Part A, 2012, DOI:10.1089/ten.TEA.2012.0023.
Grieshaber, S.E.*; Farran, A. J. E.*; Bai, S.; Kiick, K.L.; Jia, X. "Tuning the Properties of Elastin Mimetic Hybrid Copolymers via a Modular Polymerization Method", Biomacromolecules, 2012, 13(6), 1774-1786
Farran, A. J. E.; Teller, S. S.; Jia, F.; Clifton, R. J.; Duncan, R. L.; Jia, X. "Design and Characterization of a Dynamic Vibrational Culture System: Implications for Vocal Fold Tissue Engineering", Journal of Tissue Engineering and Regenerative Medicine, 2011, DOI: 10.1002/term.514
Farran, A. J. E.; Teller, S. S.; Jha, A. K.; Jiao, T.; Hule, R. A.; Clifton, R. J.; Pochan, D. P.; Duncan, R. L.; Jia, X. "Effects of Matrix Composition, Microstructure and Viscoelasticity on the Behaviors of Vocal Fold Fibroblasts Cultured in Three-Dimensional Hydrogel Networks", Tissue Engineering: Part A, 2010, 16(4), 1247-1261
Grieshaber, S. E.; Farran, A. J. E.; Lin-Gibson, S.; Kiick, K. L.; Jia, X. "Synthesis and Characterization of Elastin Mimetic Hybrid Polymers with Multiblock, Alternating Molecular Architecture and Elastomeric Properties", Macromolecules, 2009, 42(7), 2532-2541
Jiao, T.; Farran, A.; Jia, X.; Clifton, R. J. "High Frequency Measurements of Viscoelastic Properties of Hydrogels for Vocal Fold Regeneration", Experimental Mechanics, 2009, 49(2), 235-246
Korotkov, R. Y.; Ricou, P.; Farran, A. J. E. "Preferred orientation in polycrystalline SnO2 films grown by atmospheric pressure chemical vapor deposition", Thin Solid Films, 2006, 502(1-2), 79-87
Korotkov, R. Y.; Farran, A. J. E.; Culp, T.; Russo, D.; Roger, C. "Transport properties of undoped and NH3-doped polycrystalline SnO2 with low background electron concentrations", J. Appl. Phys., 2004, 96(11), 6445-6453
Conference Proceedings and Preprints
Grieshaber, S. E.; Farran, A.; Kiick, K. L.; Jia, X. "Elastin Mimetic, Cell Adhesive Multiblock Copolymers", Polym. Prepr. 2010, 51, 88-89
Farran, A. J. E.; Jia, F.; Tong, Z.; Duncan, R. L.; Jia, X. "Towards in vitro Engineering of Vocal Fold Lamina Propria: Dynamic Culture", Polym. Mat. Sci. Eng. Prepr., 2009, 101, 1126-1127
Grieshaber, S. E.; Farran, A. J. E.; Kiick, K. L.; Jia, X. "Synthesis and Characterization of Hybrid Elastin Mimetic Multiblock Copolymers with Varying RGD Density", Polym. Mat. Sci. Eng. Prepr., 2009, 101, 1365-1366
Farran, A. J. E.; Duncan, R. L.; Jia, X. "Vocal Fold Tissue Engineering: 3D Culture of Vocal Fold Fibroblasts using Biomimetic Hydrogel Matrices", Polym. Mat. Sci. Eng. Prepr., 2008, 99, 844-845
Korotkov, R. Y.; Farran, A. J. E.; Culp, T.; Russo, D.; Roger, C. "Control of the preferred orientation in a polycrystalline SnO2 films grown by MOCVD", proceedings ICCG-5, 2004, 221
Book Chapters
Farran, A. J. E.; Tong, Z.; Witt, R.L.; Jia, X. "Tissue Engineering Strategies for Vocal Fold Repair and Regeneration" In "Engineering Biomaterials for Regenerative Medicine" Bhatia, S. K. Ed., New York, NY, Springer, 253-284, 2012
Grieshaber, S. E.; Jha, A. K.; Farran, A. J. E.; Jia, X. "Hydrogels in Tissue Engineering" in "Biomaterials for Tissue Engineering: A Review of the Past and Future Trends" Burdick, J. A.; Mauck, R. L. Eds., New York, NY, Springer, 9-46, 2011
Abstracts
Farran, A. J. E.*; Jha, A. K.; Duncan, R. L.; Jia, X. "Engineering Biomimetic Microenvironments for the Functional Regeneration of Vocal Fold Lamina Propria", Podium presentation, Biomedical Engineering Society (BMES) Annual Meeting, Austin, TX, USA, November 2010
Farran, A. J. E.*; Duncan, R. L.; Jia, X. "Engineering Biomimetic Microenvironments for the Functional Regeneration of Vocal Fold Lamina Propria", Podium presentation, 3rd Annual Materials Research Society (MRS) Symposium, Newark, DE, USA, October 2010
Grieshaber, S. E.; Farran, A. J. E.*; Kiick, K. L.; Jia, X. "Elastin Mimetic Hybrid Polymers as Conducive Scaffolds for Tissue Engineering", Poster Presentation, Biomedical Engineering Society (BMES) Annual Fall Meeting, Austin, TX, October 2010
Grieshaber, S. E.*; Farran, A. J. E.; Kiick, K. L.; Jia, X. "Elastin mimetic, cell adhesive multiblock hybrid copolymers", Podium presentation, POLY, 240th American Chemical Society (ACS) National Fall Meeting, Boston, MA, USA, August 2010
Grieshaber, S. E.; Farran, A. J. E.; Kiick, K. L.; Jia, X.* "Elastin Mimetic Hybrid Polymers for Vocal Fold Tissue Engineering", Poster Presentation, Society for Biomaterials (SFB) Annual Meeting, Seattle, WA, April 2010
Farran, A. J. E.*; Tong, Z.; Jia, F.; Duncan, R. L.; Jia, X. "Tissue Engineering of Vocal Fold Lamina Propria", Podium presentation, 2nd Annual Materials Research Society (MRS) Symposium, Newark, DE, USA, October 2009
Farran, A. J. E.*; Jia, F.; Tong, Z.; Duncan, R. L.; Jia, X. "Towards in vitro Engineering of Vocal Fold Lamina Propria: Dynamic Culture", Podium presentation, Biomedical Engineering Society (BMES) Annual Meeting, Pittsburg, PA, USA, October 2009
Farran, A. J. E.*; Jia, F.; Tong, Z.; Duncan, R. L.; Jia, X. "Towards in vitro Engineering of Vocal Fold Lamina Propria: Dynamic Culture", Podium presentation, PMSE, 238th American Chemical Society (ACS) National Fall Meeting, Washington D.C., USA, August 2009
Grieshaber, S. E.*; Farran, A. J. E.; Kiick, K. L.; Jia, X. "Synthesis and Characterization of hybrid elastin mimetic multiblock copolymers with varying RGD density", Podium presentation, PMSE, 238th American Chemical Society (ACS) National Fall Meeting, Washington D.C., USA, August 2009
Farran, A. J. E.*; Jia, F.; Tong, Z.; Duncan, R. L.; Jia, X. "Tissue Engineering of Vocal Fold Lamina Propria", Poster presentation, 2nd annual Mid-Atlantic Frontiers at the Chemistry and Biology Interface (CBI) symposium, Baltimore, MD, USA, May 2009
Farran, A. J. E.*; Jia, F.; Tong, Z.; Duncan, R. L.; Jia, X. "Tissue Engineering of Vocal Fold Lamina Propria", Poster presentation, Center for Biomedical Engineering Research: Biomechanics Research Symposium, Newark, DE, USA, May 2009
Grieshaber, S. E.; Farran, A. J. E.; Lin-Gibson, S.; Kiick, K. L.; Jia, X.* "Synthesis and Characterization of Elastin Mimetic Hybrid Polymers with Alternating Molecular Architecture and Elastomeric Properties", Poster Presentation, Gordon Research Conferences (GRC): Macromolecular Materials, Ventura, CA, January, 2009
Farran, A. J. E.*; Jia, F.; Jha, A. K.; Duncan, R. L.; Jia, X. "Biomimetic Approaches for Vocal Fold Tissue Engineering", Podium presentation, Materials Research Society (MRS) Annual Fall Meeting, Boston, MA,USA, December 2008
Farran, A. J. E.*; Jia, F.; Jha, A. K.; Duncan, R. L.; Jia, X. "Biomimetic Approaches for Vocal Fold Tissue Engineering", Podium presentation, Biomedical Engineering Society (BMES) Annual Meeting, Saint-Louis, MO, USA, October 2008
Jia, F.; Farran, A. J. E.*; Duncan, R. L.; Jia, X. "High Frequency Vibrational Stimulation of Vocal Fold Fibroblasts", Poster presentation, Biomedical Engineering Society (BMES) Annual Meeting, Saint-Louis, MO, USA, October 2008
Jha, A. J.; Grieshaber, S. E.; Farran, A. J. E.; Jia, F.; Woods, M.; Jia, X.* "Synthetic Extracellular Matrices with Controlled Architectures and Improved Mechanical Properties for Tissue Engineering", Poster Presentation, Biomedical Engineering Society (BMES) Annual Meeting, St. Louis, MO, USA, October, 2008
Farran, A. J. E.*; Duncan, R. L.; Jia, X. "Vocal Fold Tissue Engineering: 3-D Culture of Vocal Fold Fibroblasts using Biomimetic Hydrogel Matrices", Podium presentation, PMSE, 236th American Chemical Society (ACS) National Fall Meeting, Philadelphia, PA, USA, August 2008
Jha, A. J.; Grieshaber, S. E.; Farran, A. J. E.; Jia, F.; Woods, M.; Jia, X.* "Tissue Engineering of Vocal Fold Lamina Propria", Poster Presentation, GRC: Signal Transduction By Engineered Extracellular Matrices, Lewiston, MI, July 11-16, 2008