Michael Hast Ph.D.
Research Assistant Professor of Orthopaedic Surgery
Director, Penn Center for Musculoskeletal Disorders Biomechanics Core
Education: Ph.D. Mechanical Engineering, 2011, Pennsylvania State University
M.S. Mechanical Engineering, 2007, Pennsylvania State University
B.S. Mechanical Engineering, 2004, Pennsylvania State University
Areas of Special Interest: Biomechanics and Performance of Orthopaedic Implants (Computational Modeling, Contact Forces, Implant Design), Biomechanics of Orthopaedic Injury, Biomechanics of Tendon Healing
Peer-Reviewed Publications:
Masada KM, Cristino DM, Dear KA, Hast MW, Mehta S. 3-D Printed Fracture Models Improve Resident Performance and Clinical Outcomes in Operative FractureManagement. J Surg Educ. 2023 May 15:S1931-7204(23)00123-X. doi:10.1016/j.jsurg.2023.04.004. Epub ahead of print. PMID: 37198080.
Glatt V, O'Toole R, Mehta S, Ricci W, Nauth A, Schemitsch E, Hast MW. Great debates in trauma biomechanics. OTA Int. 2023 May 4;6(2 Suppl):e249. doi:10.1097/OI9.0000000000000249. PMID: 37168029; PMCID: PMC10166369.
Huffman GR, Piper C, Gupta R, Hast MW. Similar Biomechanics Between the Double-Cortical Button and Docking Techniques for Ulnar Collateral LigamentReconstruction: A Cadaveric Evaluation. Orthop J Sports Med. 2023 Jan27;11(1):23259671221123342. doi: 10.1177/23259671221123342. PMID: 36743727;PMCID: PMC9893366.
Weber EL, Schmidt EC, Steinberger Z, Dardas AZ, Hast MW, Levin LS. Turnover lengthening of the ECRB tendon does not alter the biomechanical strength of PT to ECRB tendon transfer. Plast Reconstr Surg. 2022 Dec 14. doi:10.1097/PRS.0000000000010100. Epub ahead of print. PMID: 36729719.
Freedman BR, Kuttler A, Beckmann N, Nam S, Kent D, Schuleit M, Ramazani F, Accart N, Rock A, Li J, Kurz M, Fisch A, Ullrich T, Hast MW, Tinguely Y, Weber E, Mooney DJ. Enhanced tendon healing by a tough hydrogel with an adhesive side and high drug-loading capacity. Nat Biomed Eng. 2022 Oct;6(10):1167-1179. doi: 10.1038/s41551-021-00810-0. Epub 2022 Jan 3. PMID: 34980903; PMCID: PMC9250555.
Gupta R, Schmidt EC, Namdari S, Stone MA, Hast MW. The addition of cerclage wiring does not improve proximal bicortical fixation of locking plates for Type C periprosthetic fractures in synthetic humeri. Clin Biomech (Bristol, Avon). 2022 Jul;97:105709. doi: 10.1016/j.clinbiomech.2022.105709. Epub 2022 Jun 18. PMID: 35780699; PMCID: PMC10096358.
Malige A, Baghdadi S, Hast MW, Schmidt EC, Shea KG, Ganley TJ. Biomechanical properties of common graft choices for anterior cruciate ligament reconstruction: A systematic review. Clin Biomech (Bristol, Avon). 2022 May;95:105636. doi: 10.1016/j.clinbiomech.2022.105636. Epub 2022 Apr 1. PMID: 35428007.
Schmidt EC, Judkins LM, Monagharan G, Mehta S, Hast MW. Current concepts in fracture healing: temporal dynamization and applications for additive manufacturing. OTA Int. 2022 Mar 10;5(1 Suppl):e164. doi: 10.1097/OI9.0000000000000164. Erratum in: OTA Int. 2022 Jul 11;5(3): PMID: 35282393; PMCID: PMC8900457.
Bansal S, Meadows KD, Miller LM, Saleh KS, Patel JM, Stoeckl BD, Lemmon EA, Hast MW, Zgonis MH, Scanzello CR, Elliott DM, Mauck RL. Six-Month Outcomes of Clinically Relevant Meniscal Injury in a Large-Animal Model. Orthop J Sports Med. 2021 Nov 12;9(11):23259671211035444. doi: 10.1177/23259671211035444. PMID: 34796238; PMCID: PMC8593308.
Inacio JV, Cristino DM, Hast MW, Dailey HL. An Adaptable Computed Tomography-Derived Three-Dimensional-Printed Alignment Fixture Minimizes Errors in Radius Biomechanical Testing. J Biomech Eng. 2021 Nov 1;143(11):111006. doi: 10.1115/1.4051433. PMID: 34114605.
Schmidt EC, Dear KA, Hendow C, Miller L, Mehta S, Hast MW. Examining the novel use of continuous compression implants in clavicle reconstruction: A biomechanical study. Clin Biomech (Bristol, Avon). 2021 Aug;88:105437. doi: 10.1016/j.clinbiomech.2021.105437. Epub 2021 Jul 21. PMID: 34311318.
Stoeckl BD, Zlotnick HM, Farrell MJ, Fryhofer GW, Hast MW, Miller LM, Sennett ML, Baxter JR, Schaer TP, Mauck RL, Steinberg DR. The porcine accessory carpal bone as a model for biologic joint replacement for trapeziometacarpal osteoarthritis. Acta Biomater. 2021 Jul 15;129:159-168. doi: 10.1016/j.actbio.2021.05.011. Epub 2021 May 19. PMID: 34022466; PMCID:\ PMC8514079.
Tilton M, Lewis GS, Hast MW, Fox E, Manogharan G. Additively manufactured patient-specific prosthesis for tumor reconstruction: Design, process, and properties. PLoS One. 2021 Jul 14;16(7):e0253786. doi: 10.1371/journal.pone.0253786. PMID: 34260623; PMCID: PMC8279401.
Cristino DM, Schmidt EC, Metikala S, Mahmoud K, Hast MW, Farber DC. A cadaveric comparison of two methods for isolated talonavicular arthrodesis: Two- screws versus plate with integrated compression screw. Foot Ankle Surg. 2021 Jun;27(4):405-411. doi: 10.1016/j.fas.2020.05.010. Epub 2020 Jun 7. PMID: 32553424.
Eby MR, Cristino DM, Counihan M, Masada KM, Ahn J, Hast MW. Immersion in Raloxifene does not significantly improve bone toughness or screw pull-out strength in multiple in vitro models. BMC Musculoskelet Disord. 2021 May 22;22(1):468. doi: 10.1186/s12891-021-04342-1. PMID: 34022860; PMCID: PMC8141119.
Zelenski NA, Schmidt E, Chin M, Gittings D, Steinberg D, Hast MW. Flexor Pollicis Longus Tendon Wear Associated With Volar Plating: A Cadaveric Study. J Hand Surg Am. 2021 Feb;46(2):106-113. doi: 10.1016/j.jhsa.2020.07.022. Epub 2020 Sep 17. PMID: 32950317.
Bansal S, Miller LM, Patel JM, Meadows KD, Eby MR, Saleh KS, Martin AR, Stoeckl BD, Hast MW, Elliott DM, Zgonis MH, Mauck RL. Transection of the medial meniscus anterior horn results in cartilage degeneration and meniscus remodeling\ in a large animal model. J Orthop Res. 2020 Dec;38(12):2696-2708. doi: 10.1002/jor.24694. Epub 2020 Apr 23. PMID: 32285971; PMCID: PMC7735384.
Katugam K, Cox SM, Salzano MQ, De Boef A, Hast MW, Neuberger T, Ryan TM, Piazza SJ, Rubenson J. Altering the Mechanical Load Environment During Growth Does Not Affect Adult Achilles Tendon Properties in an Avian Bipedal Model. Front Bioeng Biotechnol. 2020 Sep 2;8:994. doi: 10.3389/fbioe.2020.00994. PMID: 32984280; PMCID: PMC7492247.
Tilton M, Armstrong AD, Wee H, Hast MW, Manogharan G, Lewis GS. Finite Element-Predicted Effects of Screw Configuration in Proximal Humerus Fracture Fixation. J Biomech Eng. 2020 Aug 1;142(8):081005. doi: 10.1115/1.4045907. PMID: 31913444.
Schmidt EC, Hullfish TJ, O'Connor KM, Hast MW, Baxter JR. Ultrasound echogenicity is associated with fatigue-induced failure in a cadaveric Achilles tendon model. J Biomech. 2020 May 22;105:109784. doi: 10.1016/j.jbiomech.2020.109784. Epub 2020 Apr 3. PMID: 32278525.
Hast MW, Chin M, Schmidt EC, Sanville J, Van Osten GK, Mehta S. Mechanical Effects of Bone Substitute and Far-Cortical Locking Techniques in 2-Part Proximal Humerus Fracture Reconstruction: A Cadaveric Study. J Orthop Trauma. 2020 Apr;34(4):199-205. doi: 10.1097/BOT.0000000000001668. PMID: 32197036.
Rajapakse CS, Farid AR, Kargilis DC, Jones BC, Lee JS, Johncola AJ, Batzdorf AS, Shetye SS, Hast MW, Chang G. MRI-based assessment of proximal femur strength compared to mechanical testing. Bone. 2020 Apr;133:115227. doi: 10.1016/j.bone.2020.115227. Epub 2020 Jan 9. PMID: 31926345; PMCID: PMC7096175.
Tilton M, Armstrong A, Sanville J, Chin M, Hast MW, Lewis GS, Manogharan GP. Biomechanical Testing of Additive Manufactured Proximal Humerus Fracture Fixation Plates. Ann Biomed Eng. 2020 Jan;48(1):463-476. doi: 10.1007/s10439-019-02365-3. Epub 2019 Sep 25. PMID: 31555983.
Hast MW, Chin M, Schmidt EC, Kuntz AF. Central screw use delays implant dislodgement in osteopenic bone but not synthetic surrogates: A comparison of reverse total shoulder models. J Biomech. 2019 Aug 27;93:11-17. doi: 10.1016/j.jbiomech.2019.06.004. Epub 2019 Jun 6. Erratum in: J Biomech. 2020 Mar 5;101:109628. PMID: 31204043.
Gittings DJ, Fryhofer GW, Hast MW, Steinberg DR, Levin LS, Gray BL. The Saline Load Test is Effective at Diagnosing Traumatic Arthrotomies of the Wrist. Tech Hand Up Extrem Surg. 2019 Jan 22. doi: 10.1097/BTH.0000000000000233. [Epub ahead of print] PubMed PMID: 30676429.
Cheema AN, Dardas AZ, Hast MW, Gray BL. The effects of incremental ulnar styloid osteotomies on distal radioulnar joint stability: a biomechanical cadaveric study. J Hand Surg Eur Vol. 2019 Mar 14:1753193419834858. doi:10.1177/1753193419834858. [Epub ahead of print] PubMed PMID: 30871405.
Schmidt EC, Chin M, Aoyama JT, Ganley TJ, Shea KG, Hast MW. Mechanical and Microstructural Properties of Native Pediatric Posterior Cruciate and Collateral Ligaments. Orthop J Sports Med. 2019 Feb 4;7(2):2325967118824400. doi: 10.1177/2325967118824400. eCollection 2019 Feb. PubMed PMID: 30775386; PubMed Central PMCID: PMC6362518.
Bachner EM, Schmidt EC, Chin M, Namdari S, Baxter JR, Hast MW. Parameterization of proximal humerus locking plate impingement with in vitro, in silico, and in vivo techniques. J Shoulder Elbow Surg. 2019 Feb 13. pii: S1058-2746(18)30892-9. doi: 10.1016/j.jse.2018.11.062. [Epub ahead of print] PubMed PMID: 30770316.
Soltero-Rivera M, Elliott MI, Hast MW, Shetye SS, Castejon-Gonzalez AC, Villamizar-Martinez LA, Stefanovski D, Reiter AM. Fracture Limits of Maxillary Fourth Premolar Teeth in Domestic Dogs Under Applied Forces. Front Vet Sci. 2019 Jan 30;5:339. doi: 10.3389/fvets.2018.00339. eCollection 2018. PubMed PMID: 30761310; PubMed Central PMCID: PMC6364561.
Baxter JR, Farber DC, Hast MW. Plantarflexor fiber and tendon slack length are strong determinates of simulated single-leg heel raise height. J Biomech. 2019 Mar 27;86:27-33. doi: 10.1016/j.jbiomech.2019.01.035. Epub 2019 Jan 29. PubMed PMID: 30722935.
Schmidt EC, Chin M, Aoyama JT, Ganley TJ, Shea KG, Hast MW. Mechanical and Microstructural Properties of Pediatric Anterior Cruciate Ligaments and Autograft Tendons Used for Reconstruction. Orthop J Sports Med. 2019 Jan 23;7(1):2325967118821667. doi: 10.1177/2325967118821667. eCollection 2019 Jan. PubMed PMID: 30719479; PubMed Central PMCID: PMC6348523.
Hast MW, Hanson BG, Baxter JR. Simulating contact using the elastic foundation algorithm in OpenSim. J Biomech. 2018 Nov 22. pii: S0021-9290(18)30860-1. doi: 10.1016/j.jbiomech.2018.11.025. [Epub ahead of print] PubMed PMID: 30501910.
Mehta S, Chin M, Sanville J, Namdari S, Hast MW. Use of an Additional Nonlocking Screw in Olecranon Fracture Osteosynthesis Changes Failure Mechanism. Orthopedics. 2018 Nov 26:1-7. doi: 10.3928/01477447-20181120-01. [Epub ahead of print] PubMed PMID: 30484851.
Baxter JR, Hast MW. Plantarflexor metabolics are sensitive to resting ankle angle and optimal fiber length in computational simulations of gait. Gait Posture. 2019 Jan;67:194-200. doi: 10.1016/j.gaitpost.2018.10.014. Epub 2018 Oct 17. PubMed PMID: 30366212.
Zhang K, Hast MW, Izumi S, Usami Y, Shetye S, Akabudike N, Philp NJ, Iwamoto M, Nissim I, Soslowsky LJ, Enomoto-Iwamoto M. Modulating Glucose Metabolism and Lactate Synthesis in Injured Mouse Tendons: Treatment With Dichloroacetate, a Lactate Synthesis Inhibitor, Improves Tendon Healing. Am J Sports Med. 2018 Jul;46(9):2222-2231. doi: 10.1177/0363546518778789. Epub 2018 Jun 21. PubMed PMID: 29927623.
Hast MW, Schmidt EC, Kelly JD 4th, Baxter JR. Computational optimization of graft tension in simulated superior capsule reconstructions. J Orthop Res. 2018 Oct;36(10):2789-2796. doi: 10.1002/jor.24050. Epub 2018 Jun 13. PubMed PMID: 29761555.
Hast MW, Piazza SJ. Position of the quadriceps actuator influences knee loads during simulated squat testing. J Biomech. 2018 May 17;73:227-232. doi: 10.1016/j.jbiomech.2018.03.024. Epub 2018 Mar 17. PubMed PMID: 29576314.
Mehta S, Chin M, Sanville J, Namdari S, Hast MW. Calcar screw position inproximal humerus fracture fixation: Don't miss high! Injury. 2018 Feb 11. pii:S0020-1383(18)30063-9. doi: 10.1016/j.injury.2018.02.007. [Epub ahead of print] PubMed PMID: 29452734.
Schoch B, Hast MW, Mehta S, Namdari S. Not All Polyaxial Locking ScrewTechnologies Are Created Equal: A Systematic Review of the Literature. JBJS Rev. 2018 Jan;6(1):e6. doi: 10.2106/JBJS.RVW.17.00049. PubMed PMID: 29360670.
Rozell JC, Chin M, Donegan DJ, Hast MW. Biomechanical Comparison of FullyThreaded Solid Cortical Versus Partially Threaded Cannulated Cancellous ScrewFixation for Lisfranc Injuries. Orthopedics. 2018 Jan 8:1-6. doi:10.3928/01477447-20180103-03. [Epub ahead of print] PubMed PMID: 29309714.
Mehta S, Tyler A, Hast MW: Understanding the Basics of Computational Modeling in Orthopaedics: A Non-numerical Review for Surgeons. Journal of the American Academy of Orthopaedic Surgeons. 25(10), October 2017.
Rajapakse CS, Kobe EA, Batzdorf AS, Hast MW, Wehrli FW. Accuracy of MRI-based finite element assessment of distal tibia compared to mechanical testing. Bone. 2017 Dec 24;108:71-78. doi: 10.1016/j.bone.2017.12.023.
Namdari S, Mehta S, Tierney A, Hast MW. Locking Cap Designs Improve Fatigue Properties of Polyaxial Screws in Upper Extremity Applications. J Orthop Trauma. 2017 May;31(5):275-280. doi: 10.1097/BOT.0000000000000780.
Pulos N, Yoon RS, Shetye S, Hast MW, Liporace F, Donegan DJ. Anteroinferior 2.7-mm versus 3.5-mm plating of the clavicle: A biomechanical study. Injury 2016 Jun 3. pii: S0020-1383(16)30220-0. doi: 10.1016/j.injury.2016.06.002.
Freedman BR, Gordon JA, Bhatt PB, Pardes AM, Thomas SJ, Sarver JJ, Riggin CN, Tucker JJ, Williams AW, Zanes RC, Hast MW, Farber DC, Silbernagel KG, Soslowsky LJ. Nonsurgical treatment and early return to activity leads to improved Achilles tendon fatigue mechanics and functional outcomes during early healing in an animal model. J Ortho Res2016 Apr 2. doi: 10.1002/jor.23253.
Jacobs IN, Redden RA, Goldberg R, Hast M, Salowe R, Mauck RL, Doolin EJ. Pediatric laryngotracheal reconstruction with tissue-engineered cartilage in a rabbit model. Laryngoscope. 2016 Jan;126 Suppl 1:S5-S21.
Zhang K, Asai S, Hast MW, Liu M, Usami Y, Iwamoto M, Soslowsky LJ, Enomoto-Iwamoto M. Tendon Mineralization Is Progressive and Associated with Deterioration of Tendon Biomechanical Properties, and Requires BMP-Smad Signaling in the Mouse Achilles Tendon Injury Model. Matrix Biology 2016 (Accepted for publication).
Rooney SI, Loro E, Sarver JJ, Peltz CD, Hast MW, Tseng WJ, Kuntz AF, Liu XS, Khurana TS, Soslowsky LJ. Exercise protocol induces muscle, tendon, and bone adaptations in the rat shoulder. J. Muscles Ligaments Tendons 2015 4(4):413-419.
Hast MW, Abboud JA, Soslowsky LJ. Exploring the role of hypercholesterolemia in tendon health and repair. J. Muscles Ligaments Tendons 2014 4(3): 275-279.
Hast MW, Zuskov A, Soslowsky LJ. The role of animal models in tendon research. Bone Joint Res 2014 3(6): 193-202.
Hast MW, Piazza SJ. Dual-Joint Modeling for Estimation of Total Knee Replacement Contact Forces During Locomotion. J Biomech Eng 135 (2013): 021004.
Thompson JA, Hast MW, Granger JF, Piazza SJ, Siston RA. The Biomechanical Effects of Total Knee Arthroplasty Component Malrotation: A Computer Simulation. J Orthop Res 29.7 (2011):969-975.
Landon RL, Hast MW, Piazza SJ. Robust Contact Modeling Using Trimmed NURBS Surfaces for Dynamic Simulations of Articular Contact. Comp Meth in App. Mech & Eng 198330 (2009):2339-2346.
Theses:
Hast MW: Assessment of Total Knee Replacement Performance Using Muscle-Driven Dynamic Simulations, Doctoral Dissertation in Mechanical Engineering, Pennsylvania State University, 2011.
Hast MW: Analysis of Total Knee Replacement Mechanics Using Dynamic Computer Simulations of Controlled Knee Flexions, Master's Thesis in Mechanical Engineering, Pennsylvania State University, 2007.
Awards:
First Place: American Society of Mechanical Engineers Grand Challenge to Predict In Vivo Knee Loads, 2011
Second Place: Penn State Mechanical Engineering Department Senior Design Project Competition, 2004
Eastern Orthopaedic Association's Resident/Fellow Paper Award, 2017
Young Investigator Award, American Academy of Pediatrics, 2018
NIRA Award Finalist, Orthopaedic Research Society Conference, 2020
First Place – Masters’ Level Podium Competition, SB3C Conference, 2020
Eagle Scout: Boy Scouts of America