Joeng Laboratory

Na Rae Park

Na Rae Park

Contact Information

Department of Orthopaedic Surgery
School of Medicine, University of Pennsylvania
360 Stemmler Hall,
36th Street and Hamilton Walk
Philadelphia, PA 19104
na.park@pennmedicine.upenn.edu

Education

Doctor of Philosophy
Department of Biomedical Science, Kyungpook National University School of Medicine, Daegu, Korea

Bachelor of Science
Department of Biotechnology, College of Natural Science, Kyungpook National University, Daegu, Korea

Research Experience

Postdoctoral Fellow
Mckay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, University of Pennsylvania, USA
Laboratory of Dr. Joeng, Kyu sang

Associate Research Professor
Cell and Matrix Research Institute, Kyungpook National University School of Medicine, Daegu, Korea
Laboratory of Dr. Choi, Je-Yong

Postdoctoral Fellow
Cell and Matrix Research Institute, Kyungpook National University School of Medicine, Daegu, Korea
Laboratory of Dr. Choi, Je-Yong

Publications

  1. Chae U*, Park NR*, Kim ES, Choi JY, Yim M, Lee HS, Lee SR, Lee S, Park JW, Lee DS. IDH2-deficient mice develop spinal deformities with aging. Physiol Res. 2018 Jul 17;67(3):487-494. Epub 2018 Mar 12. * These authors contributed equally to this work.
  2. Song JY, Kim SG, Park NR, Choi JY. Porcine Bone Incorporated With 4-Hexylresorcinol Increases New Bone Formation by Suppression of the Nuclear Factor Kappa B Signaling Pathway. J Craniofac Surg. 2018 Oct;29(7):1983-1990.
  3. Kwon SR, Nam SH, Park CY, Baek S, Jang J, Che X, Kwak SH, Choi YR, Park NR, Choi JY, Lee Y, Chung TD. Electrodeless Reverse Electrodialysis Patches as an Ionic Power Source for Active Transdermal Drug Delivery. Adv. Funct. Mater. 2018; 28(15) p.1705952.
  4. Kweon H, Jo YY, Seok H, Kim SG, Chae WS, Sapru S, Kundu S C, Kim DW, Park NR, Che X, Choi JY. In vivo bone regeneration ability of different layers of natural silk cocoon processed using an eco-friendly method. Macromol. Res., 2017; 25(8):806-816.
  5. Park NR, Lim KE, Han MS, Che X, Park CY, Kim JE, Taniuchi I, Bae SC, Choi JY. Core binding factor β plays a critical role during chondrocyte differentiation. J Cell Physiol, 2016; 231(1):162-171
  6. Che X*, Chi L*, Park CY, Cho GH, Park NR, Kim SG, Lee BH, Choi JY. A Novel Method to Detect Articular chondrocyte death during early stages of osteoarthritis using a non-invasive ApoPep-1 probe. Arthritis Res Ther, 2015; 17:309.
  7. Lim KE, Park NR, Che X, Han MS, Jeong JH, Kim SY, Park CY, Akiyama H, Kim JE, Ryu HM, Stein JL, Lian JB, Stein GS, Choi JY. Core binding factor β of osteoblasts maintains cortical bone mass via stabilization of Runx2 in mice. J Bone Miner Res, 2015; 30(4): 715-22
  8. Han MS, Che X, Cho GH, Park HR, Lim KE, Park NR, Jin JS, Jung YK, Jeong JH, Lee IK, Kato S, Choi JY. Functional cooperation between vitamin D receptor and Runx2 in vitamin D-induced vascular calcification. PLoS One. 2013 Dec 12;8(12):e83584.
  9. Han MS, Kim HJ, Wee HJ, Lim KE, Park NR, Bae SC, van Wijnen AJ, Stein JL, Lian JB, Stein GS, Choi JY. The cleidocranial dysplasia-related R131G mutation in the Runt-related transcription factor RUNX2 disrupts binding to DNA but not CBF-beta. J Cell Biochem. 2010 May;110(1):97-103.
  10. Jung YK, Jin JS, Jeong JH, Kim HN, Park NR, Choi JY. DICAM, a novel dual immunoglobulin domain containing cell adhesion molecule interacts with alphavbeta3 integrin. J Cell Physiol. 2008 Sep;216(3):603-14. doi: 10.1002/jcp.21438.

Selected Abstracts and Presentations

  1. Che X, Park NR, Hong YM, Han MS, Jung YK, Choi YR, Jin X, Oh GT, Kato S, Choi JY. Calbindin-D 9K mediates vascular calcification from high dose Vitamin D injection via blocking BMP signaling pathway. ASBMR 2017 Annual meeting, September 8-11, 2017, Colorado convention center, Denver, Colorado, USA
  2. Park NR, Yeo DI, Kim GH, Che X, Choi YR, Park CY, Kato S and Choi JY. Osteoclast vitamin D receptor increases bone resorption and regulates osteoblast activity in vivo. ASBMR 2016 Annual meeting, September 16-19, 2016, Georgia world congress center, Atlanta, Georgia, USA  
  3. Selected Plenary Poster Session, 2016 ASBMR Young Investigator Travel Grant
  4. Choi YR, Park CY, Che X, Park NR, Yeo DI, Kato S and Choi JY. Calcium metabolism of 6 and 17 month-old vitamin D receptor knockout mice: A pilot study. ASBMR 2016 Annual meeting, September 16-19, 2016, Georgia world congress center, Atlanta, Georgia, USA
  5. Park CY, Che X, Park NR, Han SH, Kim GH, Choi JY. Runx1/Cbfβ transcription factor complex is essential in maintaining articular cartilage. 27th Annual Mouse Molecular Genetics Conference September 29-October 3, 2014, Pacific Grove, California, USA
  6. Park NR, Lim KE, Kim JE, Taniuchi I, Bae SC, Jeong JH, Choi JY. Essential role of the Runx2-Cbfb transcription complex for endochondral bone formation. Genetics Society of american Conference, October 2-6, 2012 Asilomar conference Grounds, USA
  7. Lim KE, Park NR, Han MS, Jeong JH, Kim JE, Bae SC, Taniuchi I, Kim SY, Choi JY. Cbf-β has a Positive Role on Postnatal Bone Formation by Regulating Runx2 Stability. ASBMR 2011, September 16-20, 2011, San Diego, California, USA
  8. Park NR, Lim KE, Kim JE, Taniuchi I, Bae SC, Choi JY. Essential role of the Runx2-Cbf-β Transcription Complex for Endochondral Bone Formation. ASBMR 2011, September 16-20, 2011, San Diego, California, USA
  9. Jeong JH, Park NR, Kim HN, Lim KE, Che X, Kang SM, Kim DW, Choi JY. Nkx3.2 Inhibits Chondrocyte differentiation Through Runx2 Independent Manner. ASBMR 2010 Annual Meeting, October 15-19, 2010, Toronto, Canada
  10. Choi JY, Park NR, Lim KE, Jeong JH, Taniuchi I, Bae SC. Essential role of the Runx2-Cbf-β transcription complexes for endochondral bone formation. The 17th international RUNX workshop, July 11-14, 2010, Oriental Hotel Hiroshima, Japan
  11. Park NR, Jung YK, Kim HJ, Kim SY, Park EK, Choi JY. ANKH Mutation Causing Craniometaphyseal Dysplasia Inhibits Osteoclast Differentiation. 30th ASBMR Annual Meeting, September 12-16, 2008, Montreal, Quebec, Canada

Honors and Awards

Best Paper Award, Feb 2017
- Core binding factor β plays a critical role during chondrocyte differentiation. J Cell Physiol, 2016; 231(1):162-171, 14th winter symposium on Cell and Matrix Research Institute, Pyeongchang, Korea

Young Women Scientist Award, Oct 2016
- Core binding factor β plays a critical role during chondrocyte differentiation. J Cell Physiol, 2016; 231(1):162-171, Association of Daegu-Gyeongbuk Women In Science and Engineering, Daegu, Korea

ASBMR Young Investigator Travel Grant, Sep 2016
- Osteoclast Vitamin D Receptor Increases Bone Resorption and Regulates Osteoblast Activity in vivo. American Society for Bone and Mineral Research, Atlanta, Georgia, USA

Excellent Presentation Award, Jan 2009
- Nkx3.2 inhibits chondrocyte differentiation through Runx2 independent manner. Biomedical science annual conference 2008, Kyungpook National University School of Medicine, Daegu, Korea

 

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