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Welcome to the Skeletal Biology and Regeneration Lab

The Qin lab studies the cellular and molecular basis for skeletal development, homeostasis, aging, and disease. Osteoporosis and osteoarthritis are two common skeletal diseases that cause huge economic and social burdens to our society. We utilize cutting edge techniques, including single-cell transcriptome analysis, 3D fluorescent imaging, and genetically modified animal models, to identify mesenchymal stem and progenitor cells at various musculoskeletal sites and investigate the function of progenitors and their descendants under normal and disease conditions. In collaborating with a team of multidisciplinary scientists and clinicians, our ultimate goal is to translate the studies on fundamental mechanisms of skeletal cell function into future clinical applications.

Qin’s lab is accepting applications from creative and motivated students and postdoc trainees who can empower the lab’s work through rigorous learning and dedication. For rotation projects, please contact Dr. Qin directly.

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What's New

ASBMR PODIUM presentation for Qin Lab!
September 11, 2022
Leilei's abstract, Csf1 from marrow adipogenic precursors is required for bone resorption, has been chosen for a PODIUM presentation at the ASBMR 2022 Annual Meeting.

Paper Accepted for Publication - Qin Lab
February 21, 2022
"EGFR signaling is required for maintaining adult cartilage homeostasis and attenuating osteoarthritis progression." was accepted to be published in Journal of Bone and Mineral Research!

Congratulations to Leilei Zhong and Lutian Yao!
February 21, 2022
Congratulations to Leilei Zhong, Lutian Yao, and coauthors for their paper titled "Transient expansion and myofibroblast conversion of adipogenic lineage precursors mediate bone marrow repair after radiation." that was accepted for publication in JCI Insight!

Congratulations to Tao Gui!
February 21, 2022
Tao's paper, Superoxide dismutase-loaded porous polymersomes as highly efficient antioxidant nanoparticles targeting synovium for osteoarthritis therapy, has been accepted for publication in Biomaterials.

Congratulations to Michael Duffy!
January 01, 2022
Congratulations to Michael for receiving Penn Training Grant in Diabetes, Endocrine and Metabolic Diseases!

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