Journal Clubs
| Date | Presenter | Title | Citation |
|---|---|---|---|
| 12/1/2023 | Rebecca Betts |
Optogenetic-induced muscle loading leads to mechanical adaptation of the Achilles tendon enthesis in mice |
Ganji E, Lamia SN, Stepanovich M, Whyte N, Goulet RW, Abraham AC, Killian ML. Optogenetic-induced muscle loading leads to mechanical adaptation of the Achilles tendon enthesis in mice. Sci Adv. 2023 Jun 23;9(25):eadf4683. doi: 10.1126/sciadv.adf4683. Epub 2023 Jun 23. PMID: 37352350; PMCID: PMC10289645. |
| 10/20/23 | Mike DiStefano |
A method for defining tissue injury criteria reveals that ligament deformation thresholds are multimodal |
Luetkemeyer CM, Neu CP, Calve S. A method for defining tissue injury criteria reveals that ligament deformation thresholds are multimodal. Acta Biomater. 2023 Sep 15;168:252-263. doi: 10.1016/j.actbio.2023.07.002. Epub 2023 Jul 9. PMID: 37433358; PMCID: PMC10530537. |
| 9/15/23 | Chet Friday | Markers of Pain in 3 Different Murine Models of Posttraumatic Osteoarthritis: A Comparison Using Gait Analysis, Imaging, Histology, and Gene Expression | Croen BJ, Carballo CB, Green SJ, Sevick JL, Piacentini AN, Chen T, Rodeo SA. Markers of Pain in 3 Different Murine Models of Posttraumatic Osteoarthritis: A Comparison Using Gait Analysis, Imaging, Histology, and Gene Expression. Am J Sports Med. 2023 Aug;51(10):2711-2722. doi: 10.1177/03635465231183088. Epub 2023 Jul 13. PMID: 37439722. |
| 8/18/23 | Steph Weiss | The rat Achilles and patellar tendons have similar increases in mechanical properties but become transcriptionally divergent during postnatal development | Steffen D, Avey A, Mienaltowski MJ, Baar K. The rat Achilles and patellar tendons have similar increases in mechanical properties but become transcriptionally divergent during postnatal development. J Physiol. 2023 Sep;601(17):3869-3884. doi: 10.1113/JP284393. Epub 2023 Jul 26. PMID: 37493407. |
| 7/14/23 | Courtney Nuss | Overload in a Rat In Vivo Model of Synergist Ablation Induces Tendon Multiscale Structural and Functional Degeneration | Bloom ET, Lin LM, Locke RC, Giordani A, Krassan E, Peloquin JM, Silbernagel KG, Parreno J, Santare MH, Killian ML, Elliott DM. Overload in a Rat In Vivo Model of Synergist Ablation Induces Tendon Multiscale Structural and Functional Degeneration. J Biomech Eng. 2023 Aug 1;145(8):081003. doi: 10.1115/1.4062523. PMID: 37184932. |
| 6/23/23 | Jaime Santillan | Orientation-dependent indentation reveals the crosslink-mediated deformation mechanisms of collagen fibrils. | Ostadi Moghaddam A, Arshee MR, Lin Z, Sivaguru M, Phillips H, McFarlin BL, Toussaint KC, Wagoner Johnson AJ. Orientation-dependent indentation reveals the crosslink-mediated deformation mechanisms of collagen fibrils. Acta Biomater. 2023 Mar 1;158:347-357. doi: 10.1016/j.actbio.2023.01.005. Epub 2023 Jan 11. PMID: 36638936; PMCID: PMC10039649. |
| 5/5/2023 | Jeremy Eekhoff |
Mouse Achilles tendons exhibit collagen disorganization but minimal collagen denaturation during cyclic loading to failure |
Pedaprolu K, Szczesny SE. Mouse Achilles tendons exhibit collagen disorganization but minimal collagen denaturation during cyclic loading to failure. J Biomech. 2023 Apr;151:111545. doi: 10.1016/j.jbiomech.2023.111545. Epub 2023 Mar 12. PMID: 36944295; PMCID: PMC10069227. |
| 4/14/23 | Jacob Nixon |
Nanoscale characterization of collagen structural responses to in situ loading in rat Achilles tendons |
Silva Barreto I, Pierantoni M, Hammerman M, Törnquist E, Le Cann S, Diaz A, Engqvist J, Liebi M, Eliasson P, Isaksson H. Nanoscale characterization of collagen structural responses to in situ loading in rat Achilles tendons. Matrix Biol. 2023 Jan;115:32-47. doi: 10.1016/j.matbio.2022.11.006. Epub 2022 Nov 23. PMID: 36435426. |
| 3/31/2023 | Mitch Hallman |
Development and application of a novel in vivo overload model of the Achilles tendon in rat |
Gains CC, Giannapoulos A, Zamboulis DE, Lopez-Tremoleda J, Screen HRC. Development and application of a novel in vivo overload model of the Achilles tendon in rat. J Biomech. 2023 Apr;151:111546. doi: 10.1016/j.jbiomech.2023.111546. Epub 2023 Mar 15. PMID: 36958089. |
| 1/27/2023 | Mike DiStefano |
The role of loading in murine models of rotator cuff disease |
Abraham AC, Fang F, Golman M, Oikonomou P, Thomopoulos S. The role of loading in murine models of rotator cuff disease. J Orthop Res. 2022 Apr;40(4):977-986. doi: 10.1002/jor.25113. Epub 2021 Jun 13. PMID: 34081350; PMCID: PMC8639823. |
| 12/9/2022 | Rebecca Betts |
Substance P Inhibitor Promotes Tendon Healing in a Collagenase-Induced Rat Model of Tendinopathy |
Ko KR, Han SH, Choi S, An HJ, Kwak EB, Jeong Y, Baek M, Lee J, Choi J, Kim IS, Lee S. Substance P Inhibitor Promotes Tendon Healing in a Collagenase-Induced Rat Model of Tendinopathy. Am J Sports Med. 2022 Nov;50(13):3681-3689. doi: 10.1177/03635465221126175. Epub 2022 Oct 5. PMID: 36197354. |
| 10/7/2022 | Chet Friday |
Altered TGFB1 regulated pathways promote accelerated tendon healing in the superhealer MRL/MpJ mouse |
Kallenbach JG, Freeberg MAT, Abplanalp D, Alenchery RG, Ajalik RE, Muscat S, Myers JA, Ashton JM, Loiselle A, Buckley MR, van Wijnen AJ, Awad HA. Altered TGFB1 regulated pathways promote accelerated tendon healing in the superhealer MRL/MpJ mouse. Sci Rep. 2022 Feb 22;12(1):3026. doi: 10.1038/s41598-022-07124-4. PMID: 35194136; PMCID: PMC8863792. |
| 9/2/2022 | Thomas Leahy |
Neonatal Enthesis Healing Involves Noninflammatory Acellular Scar Formation through Extracellular Matrix Secretion by Resident Cells |
Vinestock RC, Felsenthal N, Assaraf E, Katz E, Rubin S, Heinemann-Yerushalmi L, Krief S, Dezorella N, Levin-Zaidman S, Tsoory M, Thomopoulos S, Zelzer E. Neonatal Enthesis Healing Involves Noninflammatory Acellular Scar Formation through Extracellular Matrix Secretion by Resident Cells. Am J Pathol. 2022 Aug;192(8):1122-1135. doi: 10.1016/j.ajpath.2022.05.008. Epub 2022 Jun 1. PMID: 35659946; PMCID: PMC9379688. |
| 7/22/2022 | Steph Weiss |
Tendon Progenitor Cells as Biological Augmentation Improve Functional Gait and Reduce Scar Formation after Rotator Cuff Repair |
Vervaecke AJ, Carbone AD, Abraham A, Bernstein Z, Laudier D, Verborgt O, Galatz LM, Huang AH. Tendon Progenitor Cells as Biological Augmentation Improve Functional Gait and Reduce Scar Formation after Rotator Cuff Repair. J Shoulder Elbow Surg. 2022 Jun 4:S1058-2746(22)00495-5. doi: 10.1016/j.jse.2022.05.004. Epub ahead of print. PMID: 35671924. |
| 7/1/2022 | Christelle Darrieutort-Laffite | Abaloparatide Improves Rotator Cuff Healing via Anabolic Effects on Bone Remodeling in a Chronic Rotator Cuff Tear Model of Rat With Osteoporosis: A Comparison With Denosumab | Xu J, Ye Z, Chen C, Zhang X, Han K, Wu X, Li Z, Jiang J, Yan X, Cai J, Zhao J. Abaloparatide Improves Rotator Cuff Healing via Anabolic Effects on Bone Remodeling in a Chronic Rotator Cuff Tear Model of Rat With Osteoporosis: A Comparison With Denosumab. Am J Sports Med. 2022 May;50(6):1550-1563. doi: 10.1177/03635465221079651. Epub 2022 Apr 11. PMID: 35404150. |
|
5/13/22 |
Jaime Santillan | Mechanical Response of Mouse Cervices Lacking Decorin and Biglycan During Pregnancy | Lee N, Shi L, Colon Caraballo M, Nallasamy S, Mahendroo M, Iozzo RV, Myers K. Mechanical Response of Mouse Cervices Lacking Decorin and Biglycan During Pregnancy. J Biomech Eng. 2022 Jun 1;144(6):061009. doi: 10.1115/1.4054199. PMID: 35348624; PMCID: PMC9125869. |
| 4/22/2022 | Joey Newton |
In vivo multimodal imaging of hyaluronan-mediated inflammatory response in articular cartilage |
Ruiz A, Duarte A, Bravo D, Ramos Gavilá E, Zhang C, Cowman MK, Kirsch T, Milne M, Luyt LG, Raya JG. In vivo multimodal imaging of hyaluronan-mediated inflammatory response in articular cartilage. Osteoarthritis Cartilage. 2022 Feb;30(2):329-340. doi: 10.1016/j.joca.2021.11.006. Epub 2021 Nov 11. PMID: 34774790; PMCID: PMC8792232. |
| 4/9/2022 | Zak Beach | Axin-2 lineage cells contribute to neonatal tendon regeneration | Walia B, Li TM, Crosio G, Montero AM, Huang AH. Axin2-lineage cells contribute to neonatal tendon regeneration. Connect Tissue Res. 2022 Feb 18:1-14. doi: 10.1080/03008207.2022.2036732. Epub ahead of print. PMID: 35180018. |
| 4/1/2022 | Jeremy Eckhoff | Ultrasound strain mapping of the mouse Achilles tendon during passive dorsiflexion | Mora KE, Mlawer SJ, Bae AJ, Richards MS, Loiselle AE, Buckley MR. Ultrasound strain mapping of the mouse Achilles tendon during passive dorsiflexion. J Biomech. 2022 Feb;132:110920. doi: 10.1016/j.jbiomech.2021.110920. Epub 2021 Dec 20. PMID: 34998182. |
| 3/18/22 | Maggie Tamburro | Method development and characterization of chick embryo tendon mechanical properties | Navarro J, Korcari A, Nguyen P, Bah I, AlKhalifa A, Fink S, Buckley M, Kuo CK. Method development and characterization of chick embryo tendon mechanical properties. J Biomech. 2022 Mar;133:110970. doi: 10.1016/j.jbiomech.2022.110970. Epub 2022 Jan 29. PMID: 35123205. |
| 3/4/2022 | Biao Han | Near infrared spectroscopic evaluation of biochemical and crimp properties of knee joint ligaments and patellar tendon | Torniainen J, Ristaniemi A, Sarin JK, Prakash M, Afara IO, Finnilä MAJ, Stenroth L, Korhonen RK, Töyräs J. Near infrared spectroscopic evaluation of biochemical and crimp properties of knee joint ligaments and patellar tendon. PLoS One. 2022 Feb 14;17(2):e0263280. doi: 10.1371/journal.pone.0263280. PMID: 35157708; PMCID: PMC8843223. |
| 2/11/2022 | Jordan Cohen | Obesity Impairs Enthesis Healing After Rotator Cuff Repair in a Rat Model | Bolam SM, Park YE, Konar S, Callon KE, Workman J, Monk AP, Coleman B, Cornish J, Vickers MH, Munro JT, Musson DS. Obesity Impairs Enthesis Healing After Rotator Cuff Repair in a Rat Model. Am J Sports Med. 2021 Dec;49(14):3959-3969. doi: 10.1177/03635465211049219. Epub 2021 Oct 25. PMID: 34694156. |
| 1/7/2022 | Ashley Fung | Enhanced tendon healing by a tough hydrogel with an adhesive side and high drug-loading capacity (Freedman et al., Nature Biomedical Engineering) |
Freedman BR, Kuttler A, Beckmann N, Nam S, Kent D, Schuleit M, Ramazani F, Accart N, Rock A, Li J, Kurz M, Fisch A, Ullrich T, Hast MW, Tinguely Y, Weber E, Mooney DJ. Enhanced tendon healing by a tough hydrogel with an adhesive side and high drug-loading capacity. Nat Biomed Eng. 2022 Jan 3. doi: 10.1038/s41551-021-00810-0. Epub ahead of print. PMID: 34980903. |
| 11/19/2022 | Chet Friday | Microscopic characterisation of local strain field in healing tissue in the central third defect of mouse patellar tendon at early-phase of healing | Maeda E, Kuroyanagi K, Matsumoto T. Microscopic characterisation of local strain field in healing tissue in the central third defect of mouse patellar tendon at early-phase of healing. J Mech Behav Biomed Mater. 2021 Nov;123:104702. doi: 10.1016/j.jmbbm.2021.104702. Epub 2021 Jul 31. PMID: 34365097. |
| 10/22/2021 | Ryan Leiphart |
The Scleraxis Transcription Factor Directly Regulates Multiple Distinct Molecular and Cellular Processes During Early Tendon Cell Differentiation |
Liu, Han, et al. "The Scleraxis transcription factor directly regulates multiple distinct molecular and cellular processes during early tendon cell differentiation." Frontiers in cell and developmental biology 9 (2021): 1372. |
| 9/24/2021 | Christelle Darrieutort-Laffite |
Extrinsic Macrophages Protect While Tendon Progenitors Degrade: Insights from a Tissue Engineered Model of Tendon Compartmental Crosstalk |
Stauber, Tino, et al. "Extrinsic Macrophages Protect While Tendon Progenitors Degrade: Insights from a Tissue Engineered Model of Tendon Compartmental Crosstalk." Advanced Healthcare Materials (2021): 2100741. |
| 9/3/2021 | Joey Newton |
Tendons exhibit greater resistance to tissue and molecular-level damage with increasing strain rate during cyclic fatigue |
Zitnay, Jared L., Allen H. Lin, and Jeffrey A. Weiss. "Tendons exhibit greater resistance to tissue and molecular-level damage with increasing strain rate during cyclic fatigue." Acta Biomaterialia (2021). |
| 7/30/2021 | Courtney Nuss | Enhanced Tendon-to-Bone Healing via IKKb Inhibition in a Rat Rotator Cuff Model | Golman M, Li X, Skouteris D, Abraham AA, Song L, Abu-Amer Y, Thomopoulos S. Enhanced Tendon-to-Bone Healing via IKKβ Inhibition in a Rat Rotator Cuff Model. Am J Sports Med. 2021 Mar;49(3):780-789. doi: 10.1177/0363546520985203. Epub 2021 Jan 28. PMID: 33507808. |
| 4/30/2021 | Jackie Carlson | Regulation of extracellular matrix assembly and structure by hybrid M1/ M2 macrophages | Witherel CE, Sao K, Brisson BK, Han B, Volk SW, Petrie RJ, Han L, Spiller KL. Regulation of extracellular matrix assembly and structure by hybrid M1/M2 macrophages. Biomaterials. 2021 Feb;269:120667. doi: 10.1016/j.biomaterials.2021.120667. Epub 2021 Jan 7. PMID: 33450585; PMCID: PMC7870567. |
| 3/19/2021 | Biao Han |
Load-induced regulation of tendon homeostasis by SPARC, a genetic predisposition factor for tendon and ligament injuries |
Wang T, Wagner A, Gehwolf R, Yan W, Passini FS, Thien C, Weissenbacher N, Lin Z, Lehner C, Teng H, Wittner C, Zheng Q, Dai J, Ni M, Wang A, Papadimitriou J, Leys T, Tuan RS, Senck S, Snedeker JG, Tempfer H, Jiang Q, Zheng MH, Traweger A. Load-induced regulation of tendon homeostasis by SPARC, a genetic predisposition factor for tendon and ligament injuries. Sci Transl Med. 2021 Feb 24;13(582):eabe5738. doi: 10.1126/scitranslmed.abe5738. PMID: 33627488. |
| 2/5/2021 | Mike DiStefano | Tensile mechanical changes in the Achilles tendon due to Insertional Achilles tendinopathy | Bah I, Fernandes NRJ, Chimenti RL, Ketz J, Flemister AS, Buckley MR. Tensile mechanical changes in the Achilles tendon due to Insertional Achilles tendinopathy. J Mech Behav Biomed Mater. 2020 Dec;112:104031. doi: 10.1016/j.jmbbm.2020.104031. Epub 2020 Aug 19. PMID: 32882677; PMCID: PMC8056289. |
| 1/8/2021 | Thomas Leahy | Immobilization after injury alters extracellular matrix and stem cell fate | Huber AK, Patel N, Pagani CA, Marini S, Padmanabhan KR, Matera DL, Said M, Hwang C, Hsu GC, Poli AA, Strong AL, Visser ND, Greenstein JA, Nelson R, Li S, Longaker MT, Tang Y, Weiss SJ, Baker BM, James AW, Levi B. Immobilization after injury alters extracellular matrix and stem cell fate. J Clin Invest. 2020 Oct 1;130(10):5444-5460. doi: 10.1172/JCI136142. PMID: 32673290; PMCID: PMC7524473. |
| 12/4/2020 | Matthew Stein | The effect of adipose-derived stem cells on enthesis healing after repair of acute and chronic massive rotator cuff tears in rats | Rothrauff BB, Smith CA, Ferrer GA, Novaretti JV, Pauyo T, Chao T, Hirsch D, Beaudry MF, Herbst E, Tuan RS, Debski RE, Musahl V. The effect of adipose-derived stem cells on enthesis healing after repair of acute and chronic massive rotator cuff tears in rats. J Shoulder Elbow Surg. 2019 Apr;28(4):654-664. doi: 10.1016/j.jse.2018.08.044. Epub 2018 Dec 4. PMID: 30527883. |
| 10/2/2020 | Steph Weiss | Elastin levels are higher in healing tendons than in intact tendons and influence tissue compliance | Svärd A, Hammerman M, Eliasson P. Elastin levels are higher in healing tendons than in intact tendons and influence tissue compliance. FASEB J. 2020 Aug 14. doi: 10.1096/fj.202001255R. Epub ahead of print. PMID: 32794252. |
| 9/18/2020 | Thomas Leahy | Accumulation of collagen molecular unfolding is the mechanism of cyclic fatigue damage and failure in collagenous tissues | Zitnay JL, Jung GS, Lin AH, Qin Z, Li Y, Yu SM, Buehler MJ, Weiss JA. Accumulation of collagen molecular unfolding is the mechanism of cyclic fatigue damage and failure in collagenous tissues. Sci Adv. 2020 Aug 28;6(35):eaba2795. doi: 10.1126/sciadv.aba2795. PMID: 32923623; PMCID: PMC7455178. |
| 9/4/2020 | Harina Raja | Connexin 43 Is Necessary for Murine Tendon Enthesis Formation and Response to Loading | Shen H, Schwartz AG, Civitelli R, Thomopoulos S. Connexin 43 Is Necessary for Murine Tendon Enthesis Formation and Response to Loading. J Bone Miner Res. 2020 Aug;35(8):1494-1503. doi: 10.1002/jbmr.4018. Epub 2020 Apr 22. PMID: 32227614. |
| 8/7/2020 | Snehal Shetye | β1 integrin, ILK and mTOR regulate collagen synthesis in mechanically loaded tendon cells | Mousavizadeh R, Hojabrpour P, Eltit F, McDonald PC, Dedhar S, McCormack RG, Duronio V, Jafarnejad SM, Scott A. β1 integrin, ILK and mTOR regulate collagen synthesis in mechanically loaded tendon cells. Sci Rep. 2020 Jul 28;10(1):12644. doi: 10.1038/s41598-020-69267-6. PMID: 32724089; PMCID: PMC7387456. |
| 7/24/2020 | Brittany Taylor | MRL/MpJ tendon matrix‐derived therapeutic promotes improved healing outcomes in scar‐mediated canonical tendon healing | Paredes J, Pekmezian A, Andarawis-Puri N. MRL/MpJ tendon matrix-derived therapeutic promotes improved healing outcomes in scar-mediated canonical tendon healing. J Orthop Res. 2020 May 22:10.1002/jor.24754. doi: 10.1002/jor.24754. Epub ahead of print. PMID: 32441819; PMCID: PMC7680300. |
| 7/10/2020 | Ryan Leiphart | Tgfb signaling is required for tenocyte recruitment and functional neonatal tendon regeneration | Kaji DA, Howell KL, Balic Z, Hubmacher D, Huang AH. Tgfβ signaling is required for tenocyte recruitment and functional neonatal tendon regeneration. Elife. 2020 Jun 5;9:e51779. doi: 10.7554/eLife.51779. PMID: 32501213; PMCID: PMC7324157. |
| 6/19/2020 | Ashley Fung | Heterogeneity of proteome dynamics between connective tissue phases of adult tendon | Choi H, Simpson D, Wang D, Prescott M, Pitsillides AA, Dudhia J, Clegg PD, Ping P, Thorpe CT. Heterogeneity of proteome dynamics between connective tissue phases of adult tendon. Elife. 2020 May 12;9:e55262. doi: 10.7554/eLife.55262. PMID: 32393437; PMCID: PMC7217697. |
| 6/12/2020 | Kelsey Bonilla | Photobiomodulation Does Not Influence Maturation and Mildly Improves Functional Healing of Mouse Achilles Tendons | Locke RC, Lemmon EA, Dudzinski E, Kopa SC, Wayne JM, Soulas JM, De Taboada L, Killian ML. Photobiomodulation does not influence maturation and mildly improves functional healing of mouse achilles tendons. J Orthop Res. 2020 Aug;38(8):1866-1875. doi: 10.1002/jor.24592. Epub 2020 Jan 28. PMID: 31965620. |
| 6/5/2020 | Joey Newton | Photoacoustic imaging of the uterine cervix to assess collagen and water content changes in murine pregnancy | Yan Y, Gomez-Lopez N, Basij M, Shahvari AV, Vadillo-Ortega F, Hernandez-Andrade E, Hassan SS, Romero R, MehrMohammadi M. Photoacoustic imaging of the uterine cervix to assess collagen and water content changes in murine pregnancy. Biomed Opt Express. 2019 Aug 19;10(9):4643-4655. doi: 10.1364/BOE.10.004643. PMID: 31565515; PMCID: PMC6757472. |
| 5/15/2020 | Zak Beach | Increased Collagen Turnover Impairs Tendon Microstructure and Stability in Integrin α2β1-Deficient Mice | Kronenberg D, Michel PA, Hochstrat E, Wei M, Brinckmann J, Müller M, Frank A, Hansen U, Eckes B, Stange R. Increased Collagen Turnover Impairs Tendon Microstructure and Stability in Integrin α2β1-Deficient Mice. Int J Mol Sci. 2020 Apr 18;21(8):2835. doi: 10.3390/ijms21082835. PMID: 32325713; PMCID: PMC7215526. |
| 5/22/2020 | Courtney Nuss | Low‐Dose Administration of Dexamethasone Is Beneficial in Preventing Secondary Tendon Damage in a Stress‐Deprived Joint Injury Explant Model | Connizzo BK, Grodzinsky AJ. Lose-Dose Administration of Dexamethasone Is Beneficial in Preventing Secondary Tendon Damage in a Stress-Deprived Joint Injury Explant Model. J Orthop Res. 2020 Jan;38(1):139-149. doi: 10.1002/jor.24451. Epub 2019 Sep 6. Erratum in: J Orthop Res. 2020 May;38(5):1167. PMID: 31441099; PMCID: PMC7268908. |
| 3/27/2020 | Jackie Carlson | Forced treadmill running reduces systemic inflammation yet worsens upper limb discomfort in a rat model of work-related musculoskeletal disorders | Smith TTG, Barr-Gillespie AE, Klyne DM, Harris MY, Amin M, Paul RW, Cruz GE, Zhao H, Gallagher S, Barbe MF. Forced treadmill running reduces systemic inflammation yet worsens upper limb discomfort in a rat model of work-related musculoskeletal disorders. BMC Musculoskelet Disord. 2020 Jan 30;21(1):57. doi: 10.1186/s12891-020-3085-z. PMID: 32000751; PMCID: PMC6993343. |
| 3/6/2020 | Julianne Huegel | Adaptive and innate immune cell responses in tendons and lymph nodes after tendon injury and repair | Noah AC, Li TM, Martinez LM, Wada S, Swanson JB, Disser NP, Sugg KB, Rodeo SA, Lu TT, Mendias CL. Adaptive and innate immune cell responses in tendons and lymph nodes after tendon injury and repair. J Appl Physiol (1985). 2020 Mar 1;128(3):473-482. doi: 10.1152/japplphysiol.00682.2019. Epub 2020 Jan 16. PMID: 31944888; PMCID: PMC7099435. |
| 2/28/2020 | Carrie Barnum | Tgfb signaling is critical for maintenance of the tendon cell fate | Tan GK, Pryce BA, Stabio A, Brigande JV, Wang C, Xia Z, Tufa SF, Keene DR, Schweitzer R. Tgfβ signaling is critical for maintenance of the tendon cell fate. Elife. 2020 Jan 21;9:e52695. doi: 10.7554/eLife.52695. PMID: 31961320; PMCID: PMC7025861. |
| 1/31/2020 | Steph Weiss | The effect of surgery on patellar tendinopathy: Novel use of MRI questions the exploitability of the rat collagenase model to humans | Dan MJ, Oliver RA, Crowley JD, Lovric V, Parr WCH, Broe D, Cross M, Walsh WR. The effect of surgery on patellar tendinopathy: Novel use of MRI questions the exploitability of the rat collagenase model to humans. Knee. 2019 Dec;26(6):1182-1191. doi: 10.1016/j.knee.2019.10.017. Epub 2019 Nov 6. PMID: 31706694. |
| 1/3/2020 | Thomas Leahy | Interfascicular matrix-mediated transverse deformation and sliding of discontinuous tendon subcomponents control the viscoelasticity and failure of tendons | Obuchowicz R, Ekiert M, Kohut P, Holak K, Ambrozinski L, Tomaszewski KA, Uhl T, Mlyniec A. Interfascicular matrix-mediated transverse deformation and sliding of discontinuous tendon subcomponents control the viscoelasticity and failure of tendons. J Mech Behav Biomed Mater. 2019 Sep;97:238-246. doi: 10.1016/j.jmbbm.2019.05.027. Epub 2019 May 20. PMID: 31132660. |
| 12/20/2019 | Snehal Shetye | Helical fibrillar microstructure of tendon using serial block-face scanning electron microscopy and a mechanical model for interfibrillar load transfer | Tarafder S, Brito JA, Minhas S, Effiong L, Thomopoulos S, Lee CH. In situ tissue engineering of the tendon-to-bone interface by endogenous stem/progenitor cells. Biofabrication. 2019 Nov 18;12(1):015008. doi: 10.1088/1758-5090/ab48ca. PMID: 31561236; PMCID: PMC6904927. |
| 12/13/2019 | Harina Raja | In situ tissue engineering of the tendon-to-bone interface by endogenous stem/progenitor cells | Tarafder S, Brito JA, Minhas S, Effiong L, Thomopoulos S, Lee CH. In situ tissue engineering of the tendon-to-bone interface by endogenous stem/progenitor cells. Biofabrication. 2019 Nov 18;12(1):015008. doi: 10.1088/1758-5090/ab48ca. PMID: 31561236; PMCID: PMC6904927. |
|
11/1/2019 |
Stacey Marvidis | Stem cell-derived extracellular vesicles attenuate the early inflammatory response after tendon injury and repair | Shen H, Yoneda S, Abu-Amer Y, Guilak F, Gelberman RH. Stem cell-derived extracellular vesicles attenuate the early inflammatory response after tendon injury and repair. J Orthop Res. 2020 Jan;38(1):117-127. doi: 10.1002/jor.24406. Epub 2019 Jul 26. PMID: 31286564; PMCID: PMC6917960. |
| Ashley Fung | A distinct transition from cell growth to physiological homeostasis in the tendon | Grinstein M, Dingwall HL, O'Connor LD, Zou K, Capellini TD, Galloway JL. A distinct transition from cell growth to physiological homeostasis in the tendon. Elife. 2019 Sep 19;8:e48689. doi: 10.7554/eLife.48689. PMID: 31535975; PMCID: PMC6791717. | |
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10/4/2019 |
Brittany Taylor | Is a Local Administration of Parathyroid Hormone Effective to Tendon‐to‐Bone Healing in a Rat Rotator Cuff Repair Model? | Yoon JP, Chung SW, Jung JW, Lee YS, Kim KI, Park GY, Kim HM, Choi JH. Is a Local Administration of Parathyroid Hormone Effective to Tendon-to-Bone Healing in a Rat Rotator Cuff Repair Model? J Orthop Res. 2020 Jan;38(1):82-91. doi: 10.1002/jor.24452. Epub 2019 Aug 29. PMID: 31441073. |
| Joey Newton | Multi‐Scale Loading and Damage Mechanisms of Plantaris and Rat Tail Tendons | Lee AH, Elliott DM. Multi-Scale Loading and Damage Mechanisms of Plantaris and Rat Tail Tendons. J Orthop Res. 2019 Aug;37(8):1827-1837. doi: 10.1002/jor.24309. Epub 2019 May 2. PMID: 30977538; PMCID: PMC6790141. | |
|
9/6/2019 |
Catherine Bautista | Tendon tissue microdamage and the limits of intrinsic repair | Stauber T, Blache U, Snedeker JG. Tendon tissue microdamage and the limits of intrinsic repair. Matrix Biol. 2020 Jan;85-86:68-79. doi: 10.1016/j.matbio.2019.07.008. Epub 2019 Jul 17. PMID: 31325483. |
| Ryan Leiphart | FGF signaling patterns cell fate at the interface between tendon and bone | Roberts RR, Bobzin L, Teng CS, Pal D, Tuzon CT, Schweitzer R, Merrill AE. FGF signaling patterns cell fate at the interface between tendon and bone. Development. 2019 Aug 2;146(15):dev170241. doi: 10.1242/dev.170241. PMID: 31320326; PMCID: PMC6703712. | |
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5/31/2019 |
Courtney Nuss | Post-operative Tendon Loading with Treadmill Running Delays Tendon-to-Bone Healing: Immunohistochemical Evaluation in a Murine Rotator Cuff Repair Model | Wada S, Lebaschi AH, Nakagawa Y, Carballo CB, Uppstrom TJ, Cong GT, Album ZM, Hall AJ, Ying L, Deng XH, Rodeo SA. Postoperative Tendon Loading With Treadmill Running Delays Tendon-to-Bone Healing: Immunohistochemical Evaluation in a Murine Rotator Cuff Repair Model. J Orthop Res. 2019 Jul;37(7):1628-1637. doi: 10.1002/jor.24300. Epub 2019 Apr 24. PMID: 30977544. |
| Jackie Carlson | Scleraxis lineage cells contribute to organized bridging tissue during tendon healing and identify a subpopulation of resident tendon cells | Best KT, Loiselle AE. Scleraxis lineage cells contribute to organized bridging tissue during tendon healing and identify a subpopulation of resident tendon cells. FASEB J. 2019 Jul;33(7):8578-8587. doi: 10.1096/fj.201900130RR. Epub 2019 Apr 5. PMID: 30951381; PMCID: PMC6593880. | |
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3/29/2019 |
Zak Beach | Oral Ibuprofen interferes with cellular healing responses in a murine model of achilles tendinopathy |
Bittermann A, Gao S, Rezvani S, Li J, Sikes KJ, Sandy J, Wang V, Lee S, Holmes G, Lin J, Plaas A. Oral Ibuprofen Interferes with Cellular Healing Responses in a Murine Model of Achilles Tendinopathy. J Musculoskelet Disord Treat. 2018;4(2):049. doi: 10.23937/2572-3243.1510049. Epub 2018 May 21. PMID: 30687812; PMCID: PMC6347402. |
| Ashley Rodriguez | The multiscale structural and mechanical effects of mouse supraspinatus muscle unloading on the mature enthesis | Deymier AC, Schwartz AG, Cai Z, Daulton TL, Pasteris JD, Genin GM, Thomopoulos S. The multiscale structural and mechanical effects of mouse supraspinatus muscle unloading on the mature enthesis. Acta Biomater. 2019 Jan 1;83:302-313. doi: 10.1016/j.actbio.2018.10.024. Epub 2018 Oct 17. PMID: 30342287; PMCID: PMC6343501. | |
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3/1/2019 |
Julianne Huegel | Extracellular Vesicle-Educated Macrophages Promote Early Achilles Tendon Healing | Chamberlain CS, Clements AEB, Kink JA, Choi U, Baer GS, Halanski MA, Hematti P, Vanderby R. Extracellular Vesicle-Educated Macrophages Promote Early Achilles Tendon Healing. Stem Cells. 2019 May;37(5):652-662. doi: 10.1002/stem.2988. Epub 2019 Feb 22. PMID: 30720911; PMCID: PMC6850358. |
| Yaping Ye | Duration of postoperative immobilization affects MMP activity at the healing graft-bone interface: Evaluation in a mouse ACL reconstruction model | Nakagawa Y, Lebaschi AH, Wada S, Green SJE, Wang D, Album ZM, Carballo CB, Deng XH, Rodeo SA. Duration of postoperative immobilization affects MMP activity at the healing graft-bone interface: Evaluation in a mouse ACL reconstruction model. J Orthop Res. 2019 Feb;37(2):325-334. doi: 10.1002/jor.24177. Epub 2018 Dec 13. PMID: 30431170; PMCID: PMC6411439. | |
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1/11/2019 |
Matt Counihan | Ultrastructure of tendon rupture depends on strain rate and tendon type | Chambers NC, Herod TW, Veres SP. Ultrastructure of tendon rupture depends on strain rate and tendon type. J Orthop Res. 2018 Nov;36(11):2842-2850. doi: 10.1002/jor.24067. Epub 2018 Jul 13. PMID: 29901228. |
| Thomas Leahy | Potential strain-dependent mechanisms defining matrix alignment in healing tendons | Richardson WJ, Kegerreis B, Thomopoulos S, Holmes JW. Potential strain-dependent mechanisms defining matrix alignment in healing tendons. Biomech Model Mechanobiol. 2018 Dec;17(6):1569-1580. doi: 10.1007/s10237-018-1044-5. Epub 2018 Jul 12. PMID: 30003433; PMCID: PMC6330133. | |
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11/9/2018 |
Carrie Barnum | Substrate fiber alignment mediates tendon cell response to inflammatory signaling | Schoenenberger AD, Foolen J, Moor P, Silvan U, Snedeker JG. Substrate fiber alignment mediates tendon cell response to inflammatory signaling. Acta Biomater. 2018 Apr 15;71:306-317. doi: 10.1016/j.actbio.2018.03.004. Epub 2018 Mar 10. PMID: 29530822. |
| Ashley Fung | Embryo movements regulate tendon mechanical property development | Pan XS, Li J, Brown EB, Kuo CK. Embryo movements regulate tendon mechanical property development. Philos Trans R Soc Lond B Biol Sci. 2018 Sep 24;373(1759):20170325. doi: 10.1098/rstb.2017.0325. PMID: 30249775; PMCID: PMC6158208. |