Welcome to ACE for WS

The Armellino Center of Excellence for Williams Syndrome was established in 2022 after a generous gift from Michael R. Armellino, W’61. With a vision to pioneer research and strategically bridge the gap between pediatric and adult care for individuals with Williams syndrome, our medical and behavioral health teams provide comprehensive and collaborative multidisciplinary services for individuals throughout the lifespan. We recognize every individual with WS is unique and provide individualized care plans and support to help our patients and their caregivers obtain the services they require as they transition to new stages of their lives.  


What is Williams syndrome? 

Williams syndrome (WS) is a rare genetic disorder that occurs equally across all populations. Approximately 1 in every 7,500 individuals are born with WS. Williams syndrome is a complex disorder with highly variable presentations that involve unique medical, behavioral, and developmental features that require specialized care.  

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Upcoming Events

  • September 14, 2025- Walk for Williams 

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  • September 29-30, 2025- International Conference on Research in Williams Syndrome

    • Please note: This conference is intended for research professionals and healthcare providers. For any questions or further information, please contact us at ace-ws-research@pennmedicine.upenn.edu

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Latest News

  • Director of ACE-WS Dr. Jocelyn Krebs and Her Son Rhys Featured on CBS News Philadelphia – Watch the Segment Below!
  • ACE-WS Welcomes New Medical Director, Dr. Mark Levin!

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  • Announcing the ACE for All Gift Fund.

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  • Highlights from our June Open Houses at the new ACE-WS Space. 

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  • ACE-WS Supports Transition to Adulthood Research

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  • With $25M gift, Penn Medicine and CHOP open Armellino Center for Williams syndrome 

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¿Necesita asistencia en español? Llámenos al 888-722-3497.


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